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Nifedipine Hasan 20mg is used to treat hypertension and prevent chronic stable angina pectoris. The following is some information about the uses, dosage and precautions when using Nifedipine Hasan 20mg medicine.1. What are the uses of Nifedipine Hasan 20mg?
Nifedipine Hasan 20mg drug has the main ingredient Nifedipine, is prepared in the form of round, biconvex tablets and is packaged in boxes of 3 blisters x 10 tablets or boxes of 10 blisters x 10 tablets. The use of Nifedipine Hasan 20mg is to prevent angina pectoris, especially when there is a vasoconstrictor factor as in Prinzmetal's angina; Hypertension .2. Dosage & How to take Nifedipine Hasan 20mg
Dosage:Treatment of hypertension: Take 1 tablet x 2 times/day, increase the dose to 2 tablets x 2 times/day or use 20-100mg x 1 time/day in case of need; Prophylaxis of angina: Take 1 tablet x 2 times/day, increase dose up to 2 tablets x 2 times/day in case of need. How to use:
Nifedipine Hasan 20mg is taken into the body through oral route. Take Nifedipine Hasan 20mg whole tablet with cooled boiled water. The patient should not suck or chew, break or break the tablet. Patients should schedule to take the medicine at the same time every day, the time between 2 doses is about 12 hours and not less than 4 hours.
Treatment in case of overdose:
Symptoms of drug overdose: Coma due to loss of consciousness, low blood pressure, tachycardia, elevated blood sugar, metabolic acidosis, hypoxemia, cardiogenic shock with pulmonary edema.
Treatment: Need to remove Nifedipine from the body and stabilize the heart. Remove as much nifedipine as possible, including the small intestine, to prevent absorption of the active drug. Some measures to remove the drug from the stomach can be applied:
Patients who take an overdose within 1 hour can use activated charcoal, with a dose of 50g for adults and 1g/kg for children;
Adult patient, overdose within 1 hour but in severe and life-threatening condition, gastric lavage is required;
Where the patient is taking the extended-release formulation along with an osmotic laxative, consider administering activated charcoal every 4 hours;
In case the patient has no symptoms of overdose, it is necessary to monitor for 4 hours after oral administration and 12 hours for extended-release drugs.
Since Nifedipine is not dialyzable, hemodialysis is not effective, although plasmapheresis should still be considered.
Use calcium 10 - 20ml of 10% calcium gluconate solution intravenously within 5 - 10 minutes to treat hypotension due to cardiogenic shock and arterial dilation. After the procedure, an electrocardiogram should be monitored. If the blood pressure is still not raised by calcium, use sympathomimetic vasoconstrictors such as dopamine or noradrenaline. Depending on each patient's response, there is an appropriate dose.
Atropin is effective if bradycardia or beta sympathomimetic or temporary pacemaker is used. Careful infusion to avoid cardiac overload.
3. Note when using Nifedipine Hasan 20mg
Contraindications:People with hypersensitivity to Nifedipine or any of its ingredients; People with cardiogenic shock, severe aortic stenosis; People with myocardial infarction within 1 month; People with acute attacks in chronic stable angina, especially in unstable angina; People with porphyria. Caution:
During the use of Nifedipine Hasan 20mg for treatment, if the user experiences ischemic pain or the existing pain worsens rapidly, they should stop taking the drug and contact the doctor. for advice.
People with heart failure or impaired left ventricular function should be careful while using the drug. If you have liver damage, diabetes, you need to reduce the dose. In the process of taking the drug should not use grapefruit juice, because this may affect drug metabolism. Nifedipine contained in the drug can inhibit labor. Nifedipine Hasan 20mg is known to affect the ability to drive and use machines, so use caution if you must then drive or operate machinery. Nifedipine Hasan 20mg should not be used during pregnancy, unless it is necessary to weigh the benefits and risks. Nifedipine is excreted in milk, so breast-feeding or breast-feeding should be done 3-4 hours after taking the drug to minimize Nifedipine exposure to the infant.
Side effects:
Some side effects may occur during the initial period of the patient taking the drug and subside after a few weeks or when the therapeutic dose is reduced: Swollen ankles, headache, dizziness, face redness, palpitations, fast heartbeat, nausea, diarrhea, or constipation;
Drug interactions:
Nifedipine is metabolised by the CYP P450 3A4 enzyme present in the liver and intestinal mucosa. Drugs with the potential to inhibit or induce this enzyme system may alter first-pass metabolism immediately after oral administration or alter the clearance of nifedipine.
Above is the important information about the drug Nifedipine Hasan 20mg. Users need to carefully read the instructions for use and if necessary, consult a doctor to have a reasonable use of the drug.
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