This is an automatically translated article.
Nefian medicine contains the active ingredient Lansoprazole which is indicated in the treatment of diseases of the gastrointestinal tract. The drug is in the form of tablets. Let's learn about the uses and notes when using Nefian through the article below.
1. What does Nefian do?
Nefian is indicated in the following diseases:
Patients with peptic ulcer disease; Patients with gastroesophageal reflux - oesophagitis have ulcers; Patients with Zollinger-Ellison syndrome. The use of Nefian is contraindicated in the following cases:
Patients with hypersensitivity to Lansoprazole or any component of the drug Nefian; Women who are pregnant in the first 3 months.
2. Dosage of the drug Nefian
Nefian belongs to the group of prescription drugs, so the dose prescribed by the doctor depends on the patient's condition. The drug should be taken 30 minutes before a meal (preferably before breakfast) for maximum effect. Some recommendations on dosage of Nefian in adults are as follows:
Treatment of duodenal ulcer: Oral 30mg/time/day, duration of treatment from 2 to 4 weeks; Treatment of gastric ulcers, erosive esophagitis in patients with gastroesophageal reflux disease: 30mg/time/day, duration of treatment from 4 to 8 weeks. In case the patient is resistant, the dose should be increased to 60mg/day; Treatment of Zollinger - Ellison syndrome: Oral 60-180mg/day; For patients with severe hepatic impairment who do not take more than 30 mg/day, the dose should be adjusted depending on the medical condition. Do not use Nefian in the treatment of children because there are no studies to prove its effectiveness and safety when used in this subject.
3. Undesirable effects of the drug Nefian
Common: Dizziness, headache, abdominal pain, diarrhea, nausea, constipation, dyspepsia, skin rash; Uncommon: Fatigue, increased liver enzymes, increased serum gastrin level, increased blood hemoglobin, hematocrit, protein and uric acid levels. In case of experiencing unwanted effects, the patient should stop using Nefian and consult the treating doctor.
4. Notes when using Nefian
For patients with suspected gastric ulcer, the risk of malignant gastric ulcer and gastric cancer should be excluded. Because treatment with Nefian can mask symptoms and delay diagnosis. Use caution when using Nefian in patients with liver dysfunction. The use of the drug in pregnant women should be prescribed by the treating physician based on the benefits and risks. Studies have demonstrated the ability of Lansoprazole to be excreted in human milk, therefore Nefian should not be used during lactation.
5. Drug interactions
Nefian may interact with some of the following drugs:
Lansoprazole is metabolised by the cytchrome P450 enzyme system, so Nefian can interact with drugs that are also metabolized by this enzyme system; Nefian reduces the effect of Itraconazole, Ketoconazole and drugs that require an acidic environment for absorption; The absorption of Lansoprazole is reduced when co-administered with Sucralfate. Drug interactions can occur that reduce the effectiveness of Nefian, increasing the risk of unwanted effects. Therefore, patients need to inform their doctors about the drugs and supplements they are using to ensure safety and effectiveness during treatment.
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