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Moxcor is often used in the treatment of some respiratory and urinary tract infections,... So what is the use of Moxcor and how is it used? Please read the article below for more information.
1. Uses of Moxcor
Moxcor is made in the form of hard capsules, with the main ingredient in each tablet is Amoxicillin (as Amoxicillin trihydrate) 500mg.
Amoxicillin is an antibiotic of the Aminopenicillin group, it is stable in acidic medium, has a broader spectrum of action than Benzylpenicillin. Amoxicillin is particularly active against gram-negative bacilli. Similar to other penicillins, Amoxicillin has a bactericidal effect due to its ability to inhibit the biosynthesis of mucopeptides of the bacterial cell wall.
Moxcor is indicated in the following cases:
Upper respiratory tract infections; Lower respiratory tract infections caused by pneumococcal, streptococci, non-penicillinase-producing staphylococci and H. influenza; Uncomplicated urinary tract infections; Gonorrhea ; Biliary tract infections; Skin and soft tissue infections caused by streptococcus, staphylococcus E.coli sensitive to Amoxicillin. Moxcor is contraindicated in the following cases:
People with a history of allergy to any type of Penicillin. Notes and precautions when using Moxcor:
It is necessary to periodically check liver and kidney function during long-term treatment; Serious hypersensitivity reactions may occur with the use of Moxcor in patients with a history of allergy to penicillin or other allergens. Therefore, it is necessary to carefully investigate the patient's history of allergy to penicillins, cephalosporins and other allergens. If an allergic reaction to Moxcor occurs, such as erythema, Quincke's edema, anaphylaxis, or Stevens-Johnson syndrome, Amoxicillin should be discontinued and emergency treatment given immediately.
2. Dosage and how to use Moxcor
Moxcor is used orally. The absorption of Amoxicillin is not affected by food, so you can take Moxcor before or after a meal.
Dosage of Moxcor should be according to the doctor's instructions, the reference dose is as follows:
Usually 250 - 500mg/time, every 8 hours; Children up to 10 years old can use a dose of 125 - 250mg, every 8 hours; Children under 20kg usually use a dose of 20-40 mg/kg body weight/day; Treatment of periodontal abscess using a dose of 3g, repeated after 8 hours; Treatment of uncomplicated acute urinary tract infections using 3g dose, repeated after 10-12 hours; To prevent endocarditis in susceptible individuals, a single dose of 3g should be given 1 hour before procedures such as tooth extraction; Severe or recurrent respiratory tract infections using a dose of 3g x 2 times/day; Children 3 - 10 years old with otitis media if necessary can use 750mg/time x 2 times/day for 2 days; For patients with renal impairment, the dose must be reduced according to the creatinine clearance: Cl creatinine < 10 ml/min: Use a dose of 500 mg/24 hours. Cl creatinine > 10 ml/min: Use dose of 500 mg/12 hours.
3. Side effects of Moxcor
During the use of Moxcor, you may experience side effects of the drug.
Common side effects of Moxcor include:
The rash usually appears slowly after 7 days of treatment. Less common side effects of Moxcor include:
Nausea; Vomit; Diarrhea; Erythema; maculopapular rash; Urticaria; Stevens-Johnson syndrome. Rare side effects of Moxcor include:
Slight increase in SGOT; Agitation, restlessness, insomnia, confusion, anxiety, changes in behavior and/or dizziness; Anemia; Thrombocytopenia; Thrombocytopenia purpura ; Eosinophilia; Leukopenia; Loss of granulocytes.
4. Moxcor drug interactions with other drugs
Using Moxcor with Nifedipine increases the absorption of Amoxicillin. When allopurinol is taken with Moxcor, there is an increased chance of Amoxicillin rash. There may be antagonism between the bactericide Amoxicillin in Moxcor and bacteriostatic agents such as Chloramphenicol, Tetracycline. In summary, Moxcor is commonly used in the treatment of a number of infectious diseases. To ensure safety and maximize the effectiveness of treatment, patients need to use the drug exactly as prescribed by the doctor.
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