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Mirenzine 5 is used to treat migraine, vestibular disorders, lack of concentration, agitation, muscle spasms or cold extremities... Mirenzine 5 should not be used for people with symptoms of hypersensitivity to the active ingredients. medication or are taking beta-blockers.
1. What is Mirenzine 5?
Mirenzine 5 is a group of drugs for treating migraine with the ingredient Flunarizine (in the form of Flunarizine dihydrochloride) 5 mg along with other active ingredients and excipients with just enough drug content provided by the manufacturer.
Drug form:
Dosage form: Tablets; Packaging: Box of 10 blisters x 10 tablets. Pharmacology and mechanism of action:
Flunarizine is a selective calcium antagonist. Pharmacokinetics:
Absorption: Mirenzine 5 is well absorbed from the gastrointestinal tract, reaching steady state at weeks 5 to 6 and peak concentrations within 2-4 hours of administration; Distribution: 90% protein bound; Completely metabolized by the liver; Elimination: The drug and its metabolites are excreted in the faeces via the biliary tract. The terminal elimination half-life is approximately 18 days.
2. Effects of Mirenzine 5
The effect of Mirenzine 5 is to prevent cellular calcium overload, by reducing excessive calcium influx across the cell membrane. However, flunarizine has no effect on myocardial contractility and conduction.
Mirenzine 5 is indicated for the following cases:
Prophylaxis and treatment in people with migraine; Symptoms of vestibular disorders such as dizziness, dizziness, tinnitus; People with lack of concentration, memory disorders, agitation and sleep disorders; Mirenzine 5 is indicated for patients with muscle spasticity while walking or lying down, paresthesia or cold extremities. The use of Mirenzine 5 is contraindicated in the following cases:
People with symptoms of hypersensitivity to the drug components Mirenzine 5; Have a history of depression; History of movement disorders such as extrapyramidal syndrome, Parkinson's; The patient is taking beta-blockers.
3. Dosage and how to use Mirenzine 5
How to use Mirenzine 5:
Every drug or drug is manufactured and used differently according to the route of administration. The usual routes of drug administration by drug form are: oral drugs, injections, external drugs and suppositories. Therefore, users need to carefully read the instructions on how to take Mirenzine 5 listed above from the drug user manual or as directed by a doctor.
Usual dose of Mirenzine 5:
Initial dose of Mirenzine 5: 10 mg once a day in the evening; People over 65 years old: Use 5 mg of Mirenzine medicine every 5 days. For maintenance use, the dose can be reduced to 5 mg/day. Above is the dose of Mirenzine 5 for reference. The patient should take the medicine as prescribed by the doctor. Patients should not arbitrarily change the dose of the drug without consulting the doctor.
In case of emergency or overdose of Mirenzine 5 with dangerous manifestations, it is necessary to immediately call the Emergency Center or go to the nearest local Health Facility. Relatives need to provide the doctor with a prescription for the medication the patient is taking, including prescription and non-prescription drugs, and dietary supplements.
In case you forget to take a dose, take it as soon as possible (usually it can be taken 1-2 hours after the time ordered by the doctor). However, if it is almost time for your next dose, skip the missed dose and take your next dose at the prescribed time. Do not arbitrarily double the prescribed dose.
4. Notes when using Mirenzine 5
Note before taking Mirenzine 5:
When appointing Mirenzine 5, caution should be taken in the elderly, patients with low blood pressure, kidney failure Mirenzine 5 should not be used during pregnancy because it can cause adverse effects such as miscarriage, teratogenicity, fetal malformation.... Therefore, Mirenzine 5 should not be used for pregnant women. Medicines can be passed to a baby through breastfeeding. Therefore, the drug should not be or should be used during breastfeeding.
5. Side effects when using Mirenzine 5
Some side effects that patients may encounter when using Mirenzine 5 are:
Dizziness, fatigue; Prolonged use can lead to depression. Usually these side effects go away when the patient stops taking the drug. If you experience any side effects not listed in the leaflet, please inform your doctor immediately for appropriate treatment.
6. How should Mirenzine 5 be stored?
Carefully read the instructions on drug storage information on the package and the instruction sheet for Mirenzine 5; Check the expiration date of Mirenzine 5; When not using the drug, it should be collected and handled according to the manufacturer's instructions; Conventional drugs are stored at room temperature, avoiding direct sunlight or high temperature because they can metabolize the ingredients in the drug.
Above is information about uses, dosage and usage of Mirenzine 5. Patients should carefully read the instructions for use, consult a doctor / pharmacist before using to ensure safety for health.
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