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Prosgesy 50mg is commonly used in the treatment of epilepsy with convulsions in adults and children over 4 years of age. The drug can be used alone in therapy or in combination with other epilepsy products, under the supervision of a specialist.1. What is Prosgesy 50mg? What is the effect?
Prosgesy 50mg contains the main ingredient topiramate 50mg – an active ingredient that has been approved by the FDA (US Food and Drug Administration) for use in the treatment of epilepsy since 1996.According to some documents. Research shows that the active ingredient topiramate has the ability to inhibit glutamate receptors (excitatory neurotransmitters) contributing to the increase of GABA (inhibitory neurotransmitter) activity. Besides, the active ingredient topiramate also has the ability to regulate sodium channel activity, control and limit the excessive discharge of nerve cells, thereby contributing to minimizing seizures effectively.
With the ingredient topiramate, Prosgesy 50 has the main use of reducing partial seizures, secondary generalized seizures with signs of generalized tonic-clonic seizures. In addition, the drug also helps control Lennox-Gastaut syndrome or is used in the treatment of migraine headaches, weight loss...
2. Indications and contraindications of Prosgesy 50mg
2.1. Indications Prosgesy 50mg is suitable in the treatment of epilepsy newly diagnosed or needs to be switched to monotherapy.Used as monotherapy or in combination therapy for adults and children over 2 years of age in the presence of seizures associated with Lennox-Gastaut syndrome, partial onset seizures with or without accompanied by generalized seizures with tonic-clonic seizures.
Support for migraine treatment in adults.
2.2. Contraindications Not to be used in cases of hypersensitivity to the ingredient topiramate in the drug.
3. Usage and dosage of Prosgesy 50mg
Prosgesy 50mg should be used in the evening with the following reference dose:3.1. Use in epilepsy support Adults
Start with a dose of 25mg/day during the first week of taking the drug. After 1 week of taking the drug, the dose can be increased to 25-50 mg/day, divided into 2 oral doses. Please note, however, that dose customization should be based on clinical response. Use maintenance dose at 200-400 mg, divided into 2 oral doses. Some patients can take the drug in high doses up to 600 mg/day. Children 2 years and older
Recommended dosage for children is 5 - 9 mg/kg/day, divided into 2 oral doses.
3.2. Use alone for epilepsy patients Adults: Use at a dose of 25mg/night x 1 week, then 1 to 2 weeks increase to 25-50mg/day in 2 divided doses, up to 500mg/day day. Children over 2 years old: Initial use is 1 - 3 mg/kg/night x 1 week, increase dose after 1 - 2 weeks to a limit of 1 - 3 mg/kg/day. 3.3. Use for migraines Adults use at a dose of 50-100mg/day, divided into 2 oral doses.
Please note that the above dosage is for reference only. The specific dose depends on your condition and the progress of the disease, so you need to consult your doctor or medical professional.
4. Prosgesy 50mg . side effects
During the use of Prosgesy 50mg, some common side effects include:Using Prosgesy 50mg to support the treatment of epilepsy in adults:
Drowsiness, fatigue, dizziness, numbness, abnormal coordination movement, blurred vision, decreased taste, impaired memory, diarrhea. Stimulation, weight loss, slow thinking. Nausea, lethargy, anorexia, dysarthria. Using Prosgesy 50mg to support the treatment of epilepsy in children:
Children have a feeling of fatigue, concentration disorders, poor appetite, constipation. Rash, behavioral disturbances, somnolence, lethargy. Using Prosgesy 50mg to treat epilepsy in adults, monotherapy:
Fatigue, diarrhea, asthenia, dysgeusia, weight loss. Depression, anxiety, restlessness, impaired memory.
5. Drug Interactions Prosgesy 50mg
Prosgesy 50mg has the potential to interact with some of the following drugs:Co-administration with the antiepileptic drug Phenytoin will increase the plasma concentration of Phenytoin. Concomitant use with drugs Phenytoin, Carbamazepine, Digoxin will reduce plasma concentrations of Topiramate. Concomitant use with alcohol and other CNS depressants will decrease the effectiveness of Prosgesy 50mg. Concomitant use of oral contraceptives reduces the effectiveness of oral contraceptives and increases the risk of bleeding. Co-administration with Metformin may alter the pharmacokinetics of Metformin. Co-administration with Pioglitazone requires daily monitoring of the patient's diabetes status. Concomitant use with drugs that cause kidney stones increases the risk of kidney stones. Concomitant use with Valproic acid increases blood ammonia with or without encephalopathy.
6. Some notes when using Prosgesy 50mg
For patients with renal failure, it is necessary to take the drug for a long time (from 10 to 15 days) to reach the saturation concentration in the blood plasma. Use caution when using Prosgesy 50mg for people with impaired liver function. Patients with advanced metabolic acidosis should reduce the dose or discontinue the drug if necessary. Consider adding nutrients to the body if there are signs of weight loss while taking the drug. Be careful when using the drug for drivers and machine operators because it can cause drowsiness, visual disturbances, blurred vision, dizziness... affect the ability to drive and operate machines. If you miss a dose, absolutely do not take the missed dose, just take the correct dose as directed by your doctor. If the drug overdose can lead to convulsions, drowsiness, speech disorders, low blood pressure, blurred vision, agitation, dizziness... At this point, the patient should be taken to medical facilities for treatment. remedial support. Basically, Prosgesy 50mg can reduce the number of seizures in some types of epilepsy. However, patients absolutely do not arbitrarily buy and use drugs outside the pharmacy. Instead, you should only use it when prescribed by a specialist to ensure the safest and most effective.Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
