This is an automatically translated article.
Midazolam is a sedative that can be used by both adults and children. The drug is administered during diagnosis or during treatment with or without the use of local anesthesia. Please refer to some basic information about this drug before using.
1. What are the effects of taking Midazolam?
Midazolam medicine 5mg/ml is prepared as an injection solution containing the main ingredient Midazolam Hydrochloride 5.56mg (Midazolam 5.00mg) and excipients just enough.
This is a derivative of the Imidazobenzodiazepine group known for its strong sedative and sleep-inducing properties. In addition, the drug also has anti-anxiety, convulsive and muscle relaxant effects with high efficiency.
2. Indications and contraindications
2.1. Indications Midazolam is usually prescribed by doctors in the following cases:
Used for the purpose of sedation before and during diagnosis or when treating with or without local anesthesia. The drug is also used in pre-anesthesia before induction of anesthesia, induction of anesthesia combined with sedation in anesthesia. Administer sedation in the intensive care unit. 2.2. Contraindications Do not use Midazolam in the following cases:
Patients with hypersensitivity to the Midazolam Hydrochloride component of the drug. Do not use in patients with acute, severe respiratory failure. People with congestive heart failure, liver failure, myasthenia gravis, acute or chronic lung disease, pregnant women in the first 3 months of pregnancy.
3. Dosage and usage
Midazolam 5mg/ml is used by injection with reference dose as follows:
Pre-anesthesia: 2.5 mg IV injection 5 - 10 minutes before the procedure, if necessary repeat with 1mg dose , a total dose of 5 mg. For elderly subjects, the dose should be reduced to 1-1.5 mg, children use a dose of 0.15 - 0.20 mg/kg. Induction: 10 - 15 mg IV injection in adults. Meanwhile in children IM injection 0.15 - 0.20 mg/kg + ketamine 4 - 8 mg/kg. Maintain maximum anesthesia: Use at a dose of 0.05 - 0.4 mg/kg/hour.
4. Side effects
When using Midazolam 5mg/ml, some rare side effects include:
Skin disorders with manifestations such as itching, urticaria. Nervous disorders with typical signs are decreased alertness, prolonged sedation, drowsiness, headache, dizziness, irritability, agitation, anger, convulsions... Digestive disorders with signs Symptoms such as vomiting, nausea, constipation... Respiratory and cardiovascular disorders with typical signs include respiratory failure, apnea, drop in blood pressure, vasodilation... The whole body disorder causes the patient to spasm. bronchospasm, anaphylaxis... Disturbances at the injection site causing pain, thrombophlebitis... When any abnormal signs appear, the patient should immediately contact a doctor, pharmacist or go to the hospital. nearest medical center for timely and effective treatment.
5. Some notes when using Midazolam 5mg/ml
Midazolam 5mg/ml has the ability to interact with alcohol, psychotropic drugs, sedatives, antidepressants, sleeping pills, pain relievers. Therefore, the patient absolutely should not use alcohol, beer and the above drugs while taking Midazolam.
Adults over 60 years old need to be very careful when using the drug, need to balance the appropriate dose. Patients with chronic or debilitating diseases take the drug as prescribed by the doctor. Chronic respiratory failure, chronic kidney failure, liver failure or heart failure, children with cardiovascular abnormalities are also very cautious when using the drug. Midazolam 5mg/ml is a medicine to be used only with the help of a medical professional. Therefore, patients absolutely do not arbitrarily use drugs to avoid affecting health, even endangering life.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
