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Midanir is indicated for intramuscular / intravenous injection for sedation, anxiety relief and amnesia before surgery, endoscopy or some other procedures. Let's refer to some information about the drug Midanir, you will know the most suitable way to use it.
1. Ingredients of Midanir
Each bottle of Midanir contains 5ml with the following ingredients:
Active ingredient: Midazolam content 5mg/5ml; Excipients with sufficient drug content: Natti chloride 40mg, disodium edetat 0.5mg, benzylic alcohol 55mg, sodium hydroxide just enough (for pH adjustment), hydrochloric acid 5mg, water for injection just enough 5ml.
2. What are the effects of Midanir?
Midazolam is a short-acting CNS depressant of the benzodiazepine class. Midazolam's CNS effects are dose dependent, route of administration and the presence of other drugs.Midazolam injection is indicated in the following conditions:
Intramuscular / intravenous injection for sedation, anxiety relief and amnesia before surgery; Midazolam alone or in combination with other CNS depressants for intravenous administration for sedation, anxiety relief and amnesia before or during diagnostic, therapeutic or endoscopic procedures, coronary angiography , cardiac catheterization, tumor procedures, X-rays, sutures...; Midazolam is administered intravenously as a general anesthetic prior to the use of other anesthetic agents. Midazolam can also be administered intravenously as an adjunct along with nitrogen oxide and oxygen; Midazolam in combination with a sedative for rapid control of schizophrenia associated with aggression/loss of behavioral control; It is also used for rapid control of intermittent seizures.
3. Dosage and how to use Midazolam
Pre-anesthesia:
Intravenous Midazolam dose 2.5 mg. Inject 5 - 10 minutes before the procedure, if necessary to re-establish the dose of 1mg, the total dose should not exceed 5mg. Elderly people reduce the dose of Midazolam to 1-1.5mg. Midazolam intramuscular injection 30 minutes before anesthesia for surgery: Adults use a dose of 0.07 - 0.1mg/kg, children use a dose of 0.15 - 0.20mg/kg. Induction:
Intravenous dose of Midazolam 10-15mg; In children, intramuscular injection of Midazolam 0.15 - 0.20 mg/kg in combination with ketamine 4 - 8 mg/kg; Maintain maximal anesthesia with midazolam dose 0.05 - 0.4 mg/kg/hour. The above dose of Midazolam is for reference only. The specific dose of Midazolam will depend on your condition and the progression of the disease. To get the right dose of Midazolam, patients need to consult their doctor/pharmacist.
4. Contraindications to taking Midazolam
Midazolam is contraindicated in the following cases:
Patients with hypersensitivity to Benzodiazepine and other ingredients in Midazolam; People with alcohol poisoning, congestive heart failure, liver failure, myasthenia gravis, acute or chronic lung disease; Pregnant women in the first 3 months.
5. Drug interactions
Possible interactions when using Midazolam concurrently with the following drugs and food:
Alcohol; Psychotropic drugs; Sedative; Antidepressants ; Sleeping pills; Analgesic. To avoid unwanted interactions when using Midazolam, patients should inform their doctor/pharmacist of all medications, supplements, vitamins or herbs they are taking.
6. Side effects of the drug Midazolam
Midazola drug may cause some of the following side effects for patients:
Decrease in systolic blood pressure; Increased heart rate; Respiratory failure; More dangerous is apnea.
7. Precautions when using Midazolam
When taking Midazola, the patient should not drive or operate machinery for 12 hours. Store Midazola at room temperature (15 - 25%), away from direct sunlight. Basically, Midazola is a drug used to be injected intramuscularly/intravenously for sedation, anxiety relief and amnesia before surgery, endoscopy or some other procedure. To be able to ensure the effectiveness of the drug, to avoid unwanted side effects, the patient needs to use the drug as prescribed by the doctor / pharmacist.
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