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Maxdotyl drug with anti-psychotic effect and effect on the nervous system. The following article would like to provide you with the most complete information on how to use and note when using the treatment line of Maxdotyl.
1. What is Maxdotyl?
Maxdotyl belongs to the class of psychotropic drugs used to treat mental disorders in physical diseases, short-term treatment of anxiety symptoms in adults when not responding to standard treatments.The drug includes the main ingredient is Sulpirid 50mg and other excipients: Lactose, Talc, Magnesium stearate, Sodium lauryl sulfate, hard gelatin capsule (No. 4). The drug is prepared in the form of capsules packed in boxes of 2 blisters x 15 tablets; Box of 1 bottle x 50, 100 capsules.
2. What are the effects of Maxdotyl?
Maxdotyl is indicated for use in the following cases:
Treatment of short-term symptoms of anxiety in adults who have not responded to conventional treatments. Mental disorders. Inhibitory nervous state. Severe behavioral disorders such as: self-harm, agitation, mimicking stereotypes, autism syndrome in children over 6 years old.
3. How to use Maxdotyl properly
3.1. How to take Maxdotyl is made in the form of capsules and taken orally. Patients should take the lowest starting dose and then increase it as needed.
3.2. Dosage The dose of the drug depends on the age and progress of the disease. The patient must always take the medicine as prescribed by the doctor. In case the disease progresses well and wants to stop the drug, the patient must consult the doctor before stopping the drug because stopping the drug too early may cause the disease to recur. Patients can refer to the following dosage of Maxdotyl:
Adults:
Treatment of short-term symptoms of anxiety in adults who do not respond to conventional treatments: The usual dose is 50 - 150mg Sulpiride/ days in 4 weeks. Children over 6 years old:
Treatment of severe behavioral disorders, self-harm, agitation, stereotyping, autism syndrome in children over 6 years old: The usual dose is from 5 to 10mg Sulpirid/kg /day. Elderly :
The usual dose is the same as for the adult dose, but will start at a low starting dose and then increase gradually. The starting dose is 50-100mg of Sulpiride/time, twice a day, then gradually increase to an effective dose. Renal impairment: Depending on the creatinine clearance, the dose should be reduced or the interval between doses increased.
In case of creatinine clearance 30 - 60ml/min: Sulpiride dose is 2/3 of normal human dose. In case of creatinine clearance 10 - 30ml/min: Use a dose of Sulpiride equal to 1/2 of the normal dose. In case of clearance less than 10ml/min: Use a dose of Sulpiride 1/3 of the normal dose. In addition, the interval between doses of Sulpiride can be increased from 1.5 times, 2 times and 3 times compared to normal people. However, patients with moderate to severe renal impairment should not use sulpiride. 3.3. What to do when overdose, forget dose of Maxdotyl? In case of Sulpiride overdose, patients may have dyskinesia with dystonia of the tongue and jaw stiffness, more severe Parkinson's-like syndrome, neuroleptic syndrome. In case of overdose, Maxdotyl can be used by hemodialysis to remove part of Sulpiride.
In addition, immediately contact the treating doctor or go to the Resuscitation - Emergency department at the nearest hospital. Currently, there is no specific antidote for Sulpiride overdose, using symptomatic treatment and cardiovascular resuscitation. Patients need to be continuously monitored until they recover. If a severe extrapyramidal syndrome occurs, anticholinergics should be used.
In case the patient forgets to take a dose, take Sulpiride as soon as possible. However, if the make up dose is close to the next dose, skip the make up dose and take your next dose at the scheduled time. Do not take twice the prescribed dose of Sulpiride.
4. Contraindications to taking Maxdotyl
Maxdotyl should not be used in the following cases:
Photochromic tumor. Patients with hypersensitivity to Sulpiride or any of its ingredients. Adrenal myeloma. Acute porphyria metabolism disorder. Central nervous system depression, alcohol poisoning, coma, neuroleptic drugs. Prolactin-dependent tumors such as breast cancer and prolactin pituitary adenoma. Combine Maxdotyl with Dopamine, Mequitazine, Cabergolin, Quinagolid, Rotigotin, Citalopram and Escitalopram. Children < 6 years old.
5. Maxdotyl drug interactions
Maxdotyl when combined with some drugs or food may occur specific drug interactions such as:
Central nervous system depressants, Levodopa drugs. Alcohol increases the sedating effect of Sulpiride, so avoid drinking alcohol while taking this medicine. Maxdotyl causes loss of consciousness when driving and operating machinery. Do not combine Sulpiride with non-Parkinsonian dopamine agonists such as: Quinagolid, Cabergolin, Rotigotin because they antagonize each other. Dopamine used with Sulpiride can cause or worsen mental disorders. In special cases where sedation is required for patients with Parkinson's disease who are receiving dopamine agonist therapy, the dose of Dopamine must be reduced gradually until it is completely stopped. due to neuroleptics. Morphine derivatives such as: analgesic, antitussive, neuroleptic. Sucralfate, aluminum/magnesium hydroxide antacids reduce the absorption of Sulpiride. Therefore, Maxdotyl should be taken about 2 hours after taking antacids. Lithium combined with Sulpiride will increase the ability of sulpiride to cause extrapyramidal disorders, increase the ability to bind Sulpiride to Dopaminergic D2 receptors in the brain. Concomitant use with antihypertensive drugs may increase the antihypertensive effect and cause orthostatic hypotension. To be on the safe side, please list all medications you are taking or other medical conditions you are experiencing with your doctor. So that the doctor will have the most appropriate medication direction.
6. What side effects does Maxdotyl cause?
Sulpiride is well tolerated, so side effects are usually milder and less common than with other antipsychotics. However, in the process of using Maxdotyl 50mg for treatment, there may be side effects, although not all patients encounter them. Immediately inform your doctor or pharmacist of any unwanted effects encountered while using this medicine.
Insomnia or somnolence Overstimulation Extrapyramidal syndromes such as restlessness Parkinson's syndrome. Tardive dyskinesia Malignant high fever syndrome due to neuroleptics. Hyperprolactinemia Increased lactation Amenorrhea, menstrual disorders. Gynecomastia in men. If the patient has life-threatening symptoms, the drug must be stopped immediately. Contact your doctor or pharmacist for appropriate support.
7. Pay attention to precautions when using Maxdotyl for treatment
Before using Maxdotyl for treatment, patients should carefully consult the information below.
Caution must be exercised when administering Sulpiride because it can cause neuroleptic malignant syndrome. During the course of taking the drug, if the patient has an unexplained high fever, stop taking the drug immediately because it may be a manifestation of neuroleptic malignant syndrome. Before taking Sulpiride, patients should exclude factors such as bradycardia, hypokalemia, congenital or acquired long QT interval, or should have an additional electrocardiogram. Use caution in the elderly, especially those with dementia, the risk of cerebrovascular accident because it is easy to lower blood pressure orthostatic, somnolence, easy to fall and extrapyramidal effects, risk of death. also increased with the use of antipsychotic drugs in the elderly. In case of patients with diabetes or at risk of diabetes when treated with Sulpiride, caution should be exercised. Sulpiride used for patients with renal failure should be reduced dose and closely monitored, in case of severe renal failure, drug therapy should be interrupted. Sulpiride should be used with caution in patients with epilepsy because of the potential for a lowered seizure threshold. Patients who drink alcohol or are taking drugs containing alcohol because it increases drowsiness. People with hypomania taking Sulpiride may make symptoms worse. Maxdotyl may cause drowsiness. Therefore, do not use the drug while operating machinery, driving and doing work at height that requires high concentration. At present, there are no reports of pregnant mothers taking Sulpiride causing any special malformation to the fetus. However, in theory, if continued use in late pregnancy and high doses of sulpiride can cause tachycardia, abdominal distention, increased excitability, delayed stools, tremors, increased muscle tone, run. Sulpiride can be used during pregnancy, but the neonate must be closely monitored for these symptoms. There are data to show that Sulpiride is excreted in human milk in large amounts and may affect the neonate. Therefore, do not use Sulpiride for women who are breastfeeding, if taking the drug should stop breastfeeding. Do not give Sulpiride to children under 6 years of age. In short, to ensure the highest safety and effectiveness of drug use, patients should carefully read the instructions for use of the drug or strictly follow the instructions of the doctor or pharmacist. Absolutely do not arbitrarily buy drugs to self-treat to avoid adverse effects on health.
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