Uses of Macoxy

This is an automatically translated article.

1. What is Macoxy?

What is Macoxy? Macoxy is a drug belonging to the group of drugs used to treat parasites, anti-infectives, antivirals, and antifungals. Macoxy is prepared in the form of film-coated tablets and is packaged in boxes of 1 blister x 6 tablets.
Macoxy's main ingredient is Cefpodoxime proxetil 200mg and some other excipients, just enough for one tablet.

2. What are the uses of Macoxy?

Macoxy has the pharmacodynamic properties of the active ingredient Cefpodoxime proxetil. It is an antibiotic that, when tolerated in the human body, can fight against Gram (-) and Gram (+) bacteria through the acylation of enzymes that create cell membrane binding leading to no Peptidoglyocan is synthesized and inhibits cell membrane formation.
Cefpodoxime proxetil component when entering the body, the drug will reach bioavailability in about 50% and about 30% of the drug when bound to serum proteins. The half-life in the body is about 2 hours and then it will be eliminated from the body by the kidneys.
Macoxy medicine is indicated for the treatment of patients in the following infections:
Treatment of upper respiratory tract infections including: Acute otitis media, sinusitis, tonsillitis and pharyngitis. Treatment of community-acquired acute pneumonia. Treatment of acute gonococcal infection without complications. Treatment of uncomplicated urinary tract infections. Treatment of skin and skin structure infections.

3. Dosage and how to use Macoxy

3.1. How to use the drug Macoxy 200 is prepared in the form of film-coated tablets, to be tolerated in the body by mouth, according to tablets.
Patients should note, do not break or chew the medicine while taking the medicine, you can use filtered or boiled water to cool down when taking the medicine.
3.2. Dosage The dose of Macoxy 200 depends on each subject's age, weight and course of the disease, there will be appropriate doses of Macoxy.
For adults:
Treatment of upper respiratory infections, including tonsillitis and pharyngitis: The dose used is 100mg Macoxy in 1 day, with a course of 10 days. Treatment of acute pneumonia in the community: The dose of the drug is 200mg Macoxy in 1 day, divided into 2 oral doses, the course of treatment is 14 days. Treatment of uncomplicated acute gonococcal infection: The single dose of the drug is 200mg Macoxy. Treatment of uncomplicated urinary tract infections: The dose is 100mg Macoxy in 1 day, with a course of 7 days. Treatment of skin and skin structure infections: The dose of the drug is 400mg Macoxy in 1 day, divided into 2 doses, 200mg each time, the course of treatment is 7-14 days. For children:
Treatment of acute otitis media in children: The dose is 10mg/kg/day. The maximum dose for children is 400mg Macoxy / day, divided into 2 oral doses. 10 days of treatment. Treatment of pharyngitis and tonsillitis: The dose is 10mg/kg/day. The maximum dose is 200mg Macoxy/day, divided into 2 oral doses. 10 days of treatment. For patients with renal failure: With creatinine clearance less than 30 ml/min, it is indicated to use Cefpodoxime with food. The interval between doses should be increased to 24 hours.
For patients with cirrhosis: When using Cefpodoxime to treat the disease, there is no need to adjust the dose.

4. In which case is Macoxy not used?

Macoxy drug is not used for patients with hypersensitivity or history of allergy to Cefpodoxime proxetil and other excipients contained in the drug.
Do not use Macoxy 200 for patients with Porphyrin metabolism disorders to prevent unnecessary risks causing danger to patients.

5. What to do when using Macoxy drug overdose?

In case the patient uses the drug Macoxy 200 over the allowable use, there is an increased risk of side effects with signs such as: Allergy, rash, diarrhea, vomiting, nausea. At that time, the patient should immediately stop using Macoxy and quickly take the patient to the nearest medical center, hospital for timely treatment. Remember to bring any medications that the patient is taking with them.

6. Macoxy drug interactions

Here are some Macoxy drug interactions that have been reported such as:
Cefpodoxime proxetil used in combination with antacids or H2 inhibitors may reduce the therapeutic effect of Macoxy 200mg, making the concentration of plasma concentration decreased by about 30%. When cefpodoxime is co-administered with compounds known to be nephrotoxic, renal function should be closely monitored during treatment. When administering Cefpodoxime with Probenecid, the concentration of Cefpodoxime in the blood plasma will increase. Cephalosporins in the drug will alter laboratory values ​​such as making the direct Coomb test positive. Before the patient is prescribed treatment with Macoxy, please provide the currently used drugs to the doctor or pharmacist to avoid adverse drug interactions during treatment.

7. Side effects of the drug Macoxy

During the use of Macoxy, patients may experience some unwanted side effects. Some of the adverse events reported in clinical trials were mild and transient, including:
Common:
Gastrointestinal disorders such as: Diarrhea, nausea, vomiting, abdominal pain, inflammation Colon. Rare:
Nervous disorders such as: Dizziness, headache, convulsions... Respiratory system disorders with typical symptoms such as: Wheezing, coughing, angina, breathing difficult.... Causes hypersensitivity reactions, rash, pruritus, thrombocytopenia, thrombocytopenia, leukopenia or eosinophilia. If the patient experiences any unusual symptoms/symptoms, please inform the treating doctor or pharmacist for further advice to avoid adverse health effects.

8. Notes when using Macoxy

Patients who use Macoxy drugs are at risk of convulsions that can lead to epilepsy, so do not use for patients whose occupation is a driver or operator of machinery. If you have to take medicine, do not drive or operate machinery. No dose adjustment of Macoxy is necessary for patients with cirrhosis of the liver, because Macoxy is not extensively metabolized in the liver when tolerated. Macoxy is not used for patients with viral infections. Because, the drug Macoxy only works for bacterial infections, not for viruses. In case the patient forgets to take the medicine (forgotten dose): The patient should skip the missed dose, do not take the double dose. Patients need to pay attention to the correct dose of treatment to achieve the desired results. If the medication is forgotten, the patient's ability to treat the disease will be reduced. Macoxy should be stored below 25 degrees Celsius, away from direct light and moisture. Note: Macoxy is prescribed by a doctor, patients absolutely do not use it on their own without an indication to use Macoxy.
Macoxy 200 has the main ingredient Cefpodoxime proxetil with a strength of 200mg. Macoxy is indicated for the treatment of upper respiratory tract infections, urinary tract infections,... To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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