This is an automatically translated article.
Lazifovir 300 belongs to the group of anti-parasitic drugs. The main ingredient of the drug is Tenofovir disoproxil fumarate. This drug line is indicated in the treatment of HIV type 1 infection in adults, treatment of chronic hepatitis B... However, in the process of using Lazifovir 300 drug may cause some side effects not desire.
1. What is Lazifovir 300?
Lazifovir 300 contains Tenofovir disoproxil fumarate which has the structure of a helical dieter nucleotide. This active ingredient inhibits the activity of HIV 1 reverse transcriptase by competing with the natural substrate Deoxyadenosine 5 Triphosphate.
After being attached to DNA ends the DNA chain. Furthermore, the compound Tenofovir disoproxil fumarate also inhibits hepatitis B virus DNA polymerase - the enzyme required for the virus to replicate in liver cells.
2. Uses of Lazifovir 300
Lazifovir 300 is indicated in the treatment of HIV type 1 infection in adults that can be combined with other antiretroviral drugs. However, Lazifovir 300 can also be used to prevent HIV infection in people at high risk of infection and also to be treated in combination with other antiretroviral drugs.
In addition, Lazifovir 300 is used to treat patients with chronic hepatitis B who are resistant to the lamivudine component.
However, Lazifovir 300 is also contraindicated in cases of hypersensitivity to the drug's components.
3. Dosage and how to use Lazifovir 300
Lazifovir 300 is used in the treatment of HIV infection in adults with the recommended dose of 1 tablet 300 mg once a day, possibly in combination with other antiretroviral agents. Prophylaxis of possible HIV infection by experimental exposure uses 1 tablet once a day and in combination with other drugs such as lamivudine or emtricitabine. Lazifovir 300 should be used as soon as possible after occupational exposure and within 28 days of use. For prevention of HIV infection without occupational exposure, Lazifovir 300 should be used at a dose of 1 tablet once a day and possibly in combination with at least two other antiretroviral drugs. For the treatment of chronic hepatitis B, use Lazifovir 300 with a dose of 1 tablet once a day and use it for 48 weeks. It should be noted: The above recommended treatment dose for Lazifovir 300 is only for the treatment of chronic hepatitis B. refer. Therefore, before using Lazifovir 300, patients need to be prescribed by a doctor.
4. Management of missed dose and overdose of Lazifovir 300
If you miss a dose of Lazifovir 300, use the missed dose as soon as you remember. However, if the interval between the missed dose and the next dose is too close, skip the missed dose. Patients should not double the dose of Lazifovir 300, because it can cause drug overdose. To overcome missed doses, patients can set alarms or ask relatives to remind them.
In case Lazifovir 300 is accidentally used in excess of the prescribed dose and shows some unwanted signs, it is necessary to take the patient to the emergency room immediately. However, family members can apply some preliminary treatment measures for Lazifovir 300 poisoning such as: gastric lavage and vomiting. Then take the patient to a medical facility for treatment.
5. Unexpected side effects when using Lazifovir 300
Lazifovir 300 may cause some unwanted side effects during treatment. However, with each case, the side effects of the drug can occur in varying degrees from mild to severe.
Some common side effects caused by this medicine include fatigue, drowsiness, dizziness, headache, loss of appetite, flatulence, digestive upset... These side effects can occur at any time. starting treatment or after increasing the dose of Lazifovir 300. Usually these side effects can be transient or subside over time.
However, in some cases Lazifovir 300 can cause serious unwanted side effects with rare reactions. These reactions can appear within minutes of using Lazifovir 300 or longer for a few days. When serious side effects appear, such as: peripheral neuropathy, depression, asthenia, elevated liver enzymes, increased blood triglyceride levels, hyperglycemia, neutropenia, acute renal failure, lactic acidosis , ... then the patient should stop using Lazifovir 300 and go to a medical facility for immediate medical assistance.
6. Some notes during the use of Lazifovir 300
For pregnant and lactating women, caution should be taken when using Lazifovir 300. Patients should be advised to use the drug from their doctor and carefully analyze the benefits and risks before using the drug. . Lazifovir 300 may change how it works as well as increase the effect of side effects. Therefore, to avoid drug interactions, patients should provide their doctors with a list of previously used drugs including prescription drugs, over-the-counter drugs and herbs. The above is important information about drugs. Lazifovir 300, patients should carefully read the instructions for use and use according to the dose prescribed by the doctor to achieve the best effect.
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