Uses of Latipenem 500mg

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1. Mechanism of action of Latipenem 500mg

Latipenem 500mg drug contains Meropenem which is a broad-spectrum synthetic antibiotic, belonging to the group for intravenous use. It is more stable to renal dehydropeptidase I than imipenem and does not require the use of additional enzyme inhibitors such as cilastatin.
Meropenem bactericidal has an action similar to penicillin by inhibiting bacterial cell wall synthesis. The drug has a broad spectrum of activity in vitro against both gram-negative, aerobic and anaerobic gram-positive bacteria. Furthermore, they are quite stable to the hydrolysis of beta lactamases known by most bacteria.

2. Indications and contraindications to using Latipenem 500mg

Latipenem 500mg drug is indicated for intravenous use in the treatment of infections in adults and children caused by one or more susceptible bacteria to meropenem such as pneumonia and nosocomial pneumonia, urinary tract infections, Intra-abdominal infections, gynecological infections, endometritis, pelvic pathologies, skin and skin structure infections, meningitis. Furthermore, Latipenem 500mg is also used to treat if there is a suspicion of bacterial infection in adults with febrile neutropenia as monotherapy or in combination with antiviral or antifungal agents.
Latipenem 500mg drug contains Meropenem as monotherapy or in combination with other antibacterial drugs and has been shown to be effective in the treatment of mixed infections.
Latipenem 500mg intravenously used has also shown to be effective in patients with cystic fibrosis and chronic lower respiratory tract infections when used as monotherapy or in combination with other antibacterial drugs. Bacteria are not always completely eliminated from the muscle using this method.
However, Latipenem 500mg is also contraindicated in cases of hypersensitivity to the drug's ingredients, or people who are allergic to the active ingredient, or to any carbapenem antibacterial agent. Latipenem 500mg is also not used in people with severe hypersensitivity to conditions such as anaphylaxis, severe skin reactions or beta-lactam antibacterial agents.

3. Dosage and how to use Lastinem 500mg

Dosage of Latipenem 500mg depends on the level and type of infection, as well as the current health status of the patient. The recommended dose of Latipenem 500 mg daily is 500 mg of meropenem administered intravenously every 8 hours in the treatment of pneumonia, urinary tract infections, and gynecological infections such as endometritis, skin infections, and structural infections. leather bamboo. The dose of Latipenem 500mg used for the treatment of hospital-acquired pneumonia, peritonitis, suspected bacterial infection in patients with leukopenia, sepsis is 1g meropenem. In the treatment of cystic fibrosis, the applied dose of Latipenem 500mg is 2 grams every 8 hours. It should be noted: The above recommended therapeutic dose for Latipenem 500mg is for reference only. Therefore, before using Latipenem 500mg, patients should be prescribed by a doctor.

4. Management of missed dose and overdose of Latipenem 500mg

Unintentional overdose may occur during treatment with Latipenem 500 mg, especially in patients with renal impairment. Treatment of overdose with Latipenem 500mg can be symptomatic to ameliorate the overdose. However, in normal people, Latipenem 500mg will be rapidly eliminated by the kidneys. But in patients with renal failure, hemodialysis will remove meropenem and its metabolites.

5. Unwanted side effects when using Latipenem 500mg

Latipenem 500mg medicine may cause some unwanted side effects during treatment. However, for each case, the side effects of Latipenem 500mg can occur in varying degrees from mild to severe.
Some common side effects caused by Latipenem 500mg include: inflammation, thrombophlebitis, pain at injection site... These side effects may occur at the beginning of treatment or after increasing the dose. 500mg dose of Latipenem. Usually the side effects associated with Latipenem 500mg may be transient or subside over time.
However, in some cases Latipenem 500mg can cause serious unwanted side effects with rare reactions. These reactions may appear within minutes of using Latipenem 500mg or longer for a few days. In the presence of serious adverse events such as rash, pruritus and systemic allergic reactions, Steven Johnson syndrome, toxic skin necrosis, thrombocytosis, eosinophilia, hemolytic anemia, increased concentration of active ingredients in liver function, ... then the patient should stop using Latipenem 500mg and go to a medical facility for immediate medical assistance.
Some notes during the use of Latipenem 500mg:
For pregnant and lactating women, caution should be exercised when using Latipenem 500mg. Patients should be advised to use Latipenem 500mg from their doctor, and carefully analyze the benefits and risks before using the drug. Latipenem 500mg may change its ability to work as well as increase the effect of side effects. Therefore, to avoid this situation, the patient should provide the doctor with a list of previously used drugs including prescription drugs, non-prescription drugs and herbs... Above is important information about Latipenem 500mg drug. Patients should carefully read the instructions for use and use according to the dose prescribed by the doctor to achieve the best effect.
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