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Forlen is a drug belonging to the group of synthetic antibiotics oxazolidinon. The drug is used to treat infections caused by Gram (+) strains of bacteria such as community-acquired pneumonia, complex skin and soft tissue inflammation,... The following article will provide detailed information about Forlen.1. What is Forlen?
Forlen (Linezolid) is a drug belonging to the group of synthetic oxazolidinon antibiotics whose main ingredient is Linezolid. Linezolid is an oxazolidinon bacteriostatic agent, which inhibits ribosomal protein synthesis. The drug has a spectrum of activity against gram (+) bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterobacteria and is active against gram (-) bacteria in vitro.
After being absorbed from the gastrointestinal tract, about 31% of Linezolid is bound to plasma proteins and rapidly distributed into tissues: bone, fat, lung, muscle, fluid in skin blisters and cerebrospinal fluid marrow
2. Uses of Forlen
Forlen is used in the treatment of infections including cases of suspected or confirmed sepsis caused by susceptible strains of aerobic or anaerobic Gram (+) bacteria such as: Pneumonia Hospital , community-acquired pneumonia, skin and soft tissue infections, methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci Forlen includes:
In case the patient is allergic to any of the ingredients. history of hypertension, chromodermal celluloma, thyrotoxicosis. Linezolid should not be used in patients with carcinoid syndrome and in patients taking medications for serotonin syndrome.
3. Dosage – How to take Forlen
Patients should take the drug during or after meals because Forlen (Linezolid) is almost completely absorbed from the gastrointestinal tract (≈100%). The following are the recommended doses of Forlen:
Adults and adolescents (> 11 years of age)
Nosocomial pneumonia, including cases associated with sepsis, community acquired pneumonia, including All cases associated with sepsis, skin and soft tissue infections, including cases with sepsis: 600 mg IV or orally* every 12 hours, duration of treatment Recommended (number of days of continuous use): 10-14 days. Enterococcus infections, including vancomycin-resistant strains and cases associated with sepsis: 600 mg IV or orally* every 12 hours, recommended duration of treatment (number of days of continuous dosing): 14 - 28 days. Children (<11 years)
Nosocomial pneumonia, including cases with sepsis, community-acquired pneumonia, including cases with sepsis, skin infections and soft tissue, including cases associated with sepsis: 10mg/10kg intravenously or orally every 8 hours, recommended duration of treatment (number of days of continuous use): 10-14 days. Enterococcus infections, including vancomycin-resistant strains and cases associated with sepsis: 10mg/10kg IV or orally every 8 hours, recommended duration of treatment (number of days of continuous administration) : 14 - 28 days. Forlen dosage may vary depending on the condition, severity of the disease, and the underlying disease. So you need to carefully read the instructions for use of Forlen listed on the package, the drug leaflet and the doctor's instructions. Do not arbitrarily change the dose, to avoid affecting the treatment results, and may even cause harm to health if overdosed
When taking an overdose of Forlen, the patient needs supportive care. , maintaining glomerular filtration helps to eliminate 30% of the dose of linezolid.,... immediately contact 911 emergency services for instructions and help or take the patient to the nearest medical facility immediately to have timely treatment plan.
If during the course of taking the medicine, you forget a dose, take the missed dose as soon as possible. However, you should not take it too close to your next dose to avoid an overdose. If you have any questions regarding the use of the drug, the dosage, as well as the duration of taking Forlen or the medical condition you are having, please immediately contact a qualified doctor for specific advice.
4. Side effects when using the drug Forlen.
Forlen may cause special side effects with prolonged use such as insomnia, anemia, discoloration of the tongue, taste disturbances, lactic acidosis, visual and peripheral neuropathy, reversible myelosuppression. Recovery includes anemia, leukopenia, triclonal peripheral blood count, thrombocytopenia, transient ischemia, renal failure, and Stevens-Johnson syndrome.
If mild allergic manifestations appear, you should stop using the drug. In case of severe hypersensitivity, you need to immediately notify the treating doctor/medical staff for timely handling.
5. Notes and cautions before taking Forlen
The subjects to note before taking Forlen: people with a history of myelosuppression, renal failure (CrCl < 30 ml/min), uncontrolled hypertension, adrenal myeloma, hyperthyroidism, infections chronic, history of seizures, depression, schizophrenia or acute comatose states. For patients on hemodialysis, the drug should be administered after hemodialysis. For patients on peritoneal dialysis, it is not known whether linezolid or its metabolites are excluded by peritoneal dialysis. Forlen causes adverse changes in animal fetuses, but there are no adequate studies on its use in humans. Therefore, pregnant women should consult a doctor / pharmacist before intending to use Forlen. Avoid combining Forlen with drugs such as adrenergic, dopamine, epinephrine, phenylpropanolamine and pseudoephedrine. Tramadol, Monoamine oxidase enzyme inhibitor (original name: Monoamine oxidase inhibitor: MAOIs) During the use of drugs to avoid unnecessary interactions, affecting the effectiveness of treatment. You need to inform the treating doctor / pharmacist about the drugs you are using or have recently used and carefully read the instructions for use of Forlen before taking.
Above is some information about the use of Forlen medicine, if you need advice or have any questions, please contact a qualified doctor / pharmacist for answers.
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