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Kuniclav Tablet 625mg is an antibiotic with the main ingredients being Amoxicillin and Clavulanic Acid. The drug is prepared in the form of film-coated tablets and is used in the treatment of infections or prophylaxis of post-operative infections for patients.
1. Effects of Kuniclav Tablet 625mg
With the main ingredients Amoxicillin and clavulanic acid, the main effect of Kuniclav Tablet 625mg is anti-infective, anti-viral and anti-fungal. Belonging to the beta - lactam family, amoxicillin has been studied to have a fairly stable effect in acidic environments, and the antibacterial spectrum is also broader than benzyloenicillin. The antibacterial spectrum of Kuniclav Tablet can include the following bacteria
Streptococcus Staphylococci that are not able to produce Penicillinase, H. influenzae Diplococcus pneumoniae, N. gonorrhoeae, E. Coli and Proteus mirabilis. Kuniclav Tablet 625mg is stable in the acidic environment of gastric juice. Absorption of this antibiotic, unaffected by food, occurs more rapidly from the gastrointestinal tract than ampicillin. When Kuniclav Tablet 625 mg and ampicillin were administered at the same dose in 2 different patients, peak plasma concentrations of amoxicillin were at least 2 times higher. According to clinical studies, 60% of an oral dose of Kuniclav Tablet 625mg is excreted in the urine within 6-8 hours of ingestion.
2. Indications for use of Kuniclav Tablet 625mg
Amoxicillin's broad antibiotic spectrum makes Kuniclav Tablet 625mg diverse in the treatment of bacterial infections.
Used in the treatment of upper respiratory tract infections Biliary tract infections People with gonorrhea Skin infections, muscle infections caused by streptococcus or staphylococcus aureus Treatment of urinary tract infections uncomplicated Respiratory tract infections Lower respiratory tract due to streptococcus, pneumococci, staphylococcus that do not secrete H.influenzae and penicillinase Prophylaxis of infection after surgery in patients
3. Contraindications to using Kuniclav Tablet 625mg
The following cases are contraindicated to use Kuniclav Tablet 625mg
Patients with a history of hypersensitivity to Amoxicillin, Clavulanic acid or penicillin antibiotics Patients with a history of cholestatic jaundice and liver / kidney dysfunction Patients with kidney failure or on hemodialysis, poor health. Patients with mononucleosis.
4. Dosage of Kuniclav Tablet 625mg
Dosage for adults and children over 12 years old: 2 Kuniclav Tablet 625mg / time / 8 hours, if the condition is severe, the dose can be increased by taking the drug every 6 hours. Maximum dose 1 day 7.2g (12 tablets) Dosage for children 3 months to under 12 years: 30mg/kg/time/8 hours, if the condition is severe, the dose can be increased by taking the drug every 6 hours. Dosage for children 7 days old - 3 months old: 30mg/kg/time/8 hours Dosage for children under 7 days old: 39mg/kg/12 hours. Prophylactic dose for patients during and after surgery: 1.2g under anesthesia. If surgery is prolonged, 1.2/times, 3-4 doses within 24 hours. Dosage for patients with renal failure: Creatinine clearance from 10 to 30mL/min: 1.2 g initially, then 600 mg/time/12 hours; Creatinine clearance < 10 mL/min: 1.2 g initially, then 600 mg every 24 hours.
5. Side effects of drugs
According to clinical studies, Kuniclav Tablet 625mg causes common side effects such as diarrhea, stomach pain, nausea, skin rash, urticaria, difficulty breathing, difficulty swallowing, vaginal discharge with itching. , yellowing of the skin or eyes. If you experience any of the above symptoms, contact your doctor immediately to advise you to discontinue the drug or reduce the dose.
6. Precautions when using Kuniclav Tablet 625mg
Some notes when using Kuniclav medicine, patients need to remember to avoid reducing drug effects and experiencing unwanted side effects.
Concurrent use of Kuniclav Tablet 625mg with Probenecid is not recommended because Probenecid will increase the concentration of Amoxicillin in the blood, easily causing side effects. Do not use Kuniclav Tablet 625mg with other anticoagulants, which may prolong the patient's blood clotting time abnormally. Concomitant use of Kuniclav Tablet 625mg and Allopurinol may increase the likelihood of rash in patients. Do not combine Kuniclav Tablet 625mg with oral contraceptives, Kuniclav Tablet 625mg will reduce estrogen reabsorption and reduce the effectiveness of oral contraceptives. pregnant. Patients using Kuniclav Tablet 625mg may give false positive test in urine Glucose concentration test A. Kuniclav Tablet 625mg is effective in treating respiratory, urinary and infectious diseases. skin bacteria. The drug can be used for both children and adults, with the dose prescribed by the doctor. Patients take the drug as prescribed to get the best effect of Kuniclav Tablet 625mg.
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