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Abitrax is used to treat urogenital respiratory tract infections, blood infections, and meningitis. The drug is administered via intramuscular route, injection or intravenous infusion.1. What is Abitrax?
Abitrax drug has the main ingredient is Ceftriaxone in the form of Ceftriaxone Sodium with the content of 1g.
Ceftriaxone belongs to the 3rd generation Cephalosporin antibiotic line, has broad antibacterial activity against many Gram (- ) bacteria, even against Streptococcus bacteria. Ingredients: Ceftriaxone in the form of Ceftriaxone Sodium 1g is prepared in the form of powder for injection, vials of 1g.
2. Effects of Abitrax
Abitrax has a direct effect on many Gram (-) bacteria and Streptococcus strains, so it is used in the treatment of bacterial and viral infections such as:
Meningitis, sepsis. Upper respiratory tract infections (pneumonia, otitis media), lower respiratory tract infections Urinary tract infections - kidney. Gonorrhea, syphilis, typhoid Infections of bones, joints, skin, soft tissues and skin ulcers. Infections in patients with reduced resistance Intra-abdominal infections (peritonitis, biliary tract infections, gastro-intestinal tract infections). In addition to the main effect of treating severe infections, Abitrax is also used for prophylaxis in surgery and endoscopy.
3. Contraindications to use Abitrax
Note the contraindications of the drug Abitrax
Patients with hypersensitivity to the Cephalosporin antibiotic line, a history of anaphylactic reactions to penicillin, ceftriaxone. If Lidocaine is used as a solvent for drug preparation, it should not be used in patients who are allergic to Lidocaine. Do not use Abitrax in premature infants. In patients with renal failure, caution should be taken when using Abitrax.
4. Dosage of Abitrax
Abitra x is one of the antibiotics used by injection, so the dose needs to be calculated accurately in the respective subjects.
Intravenous administration: Dissolve 1g with 10ml before injection. Intravenous use: Dissolve 2g in 40ml of 0.9% NaCl or 5% Dextrose (Calcium-free) before infusion. For adults: The allowable dose of Abitrax is 1-2g/day, injected once or divided into 2 times. For children: The allowable dose of Abitrax is 50mg - 75mg/kg, can be injected once or divided equally into 2 times. The total daily dose should not exceed 2g. For people being treated for meningitis: The starting dose is 100mg/kg (not to exceed 4g). After the end of the starting dose, the dose will be 100mg/kg/day, injected once a day. The duration of taking Abitrax for people with meningitis is 7-14 days. For infants, the dose is 50mg/kg/day. For patients with renal and hepatic impairment: Creatinine clearance below 10ml/min, the dose of Abitrax should not exceed 2g within 24 hours. In the case of patients on hemodialysis, a dose of 2g should be administered at the end of the dialysis session to maintain effective drug concentrations until the following dialysis session within 72 hours.
5. Notes when using Abitrax
Cephalosporin antibiotics can increase the possibility of nephrotoxicity by gentamicin, colistin, furosemide, note when using the combination of the above drugs.
Abitrax is excreted in milk at low concentrations, therefore caution should be exercised when administering the drug to a nursing woman.
In case the patient skips a dose during the course of taking the medicine, take the next dose at the time prescribed by the doctor, do not take double the dose prescribed by the doctor.
6. Side effects when using Abitrax
Abitrax is well tolerated by injection, but in some cases, side effects are still recorded as follows: Skin sensitization, jaundice, increased liver enzymes, kidney failure, colitis. Patients need to consult their doctor, specify the history of allergies before the doctor prescribes Abitrax. When you have the above symptoms, go to the nearest local medical facility for timely treatment.
Intravenous Abitrax is an antibiotic belonging to the 3rd generation Cephalosporin family. The drug is used to treat respiratory tract infections, purulent meningitis and severe infections in other organs.
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