Uses of Klavunamox 400/57mg

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Klavunamox 400/57mg is a group of drugs indicated for the treatment of infections caused by susceptible strains such as upper respiratory tract infections: sinusitis, tonsillitis, otitis media. So is Klavunamox a heavy or mild antibiotic? What are the uses of Klavunamox 400/57mg? The following article will help you better understand Klavunamox.

1. What are the uses of Klavunamox 400/57mg?

1.1. What is Klavunamox antibiotic? Klavunamox belongs to the group of antibiotics with the main ingredients including Amoxicillin and Clavulanic Acid. The drug is effective in the treatment of severe upper respiratory tract infections, lower respiratory tract infections, severe urinary-genital infections, skin and soft tissue infections or bone and joint infections... in the form of cells. The preparation is powder for oral suspension.
The main ingredients of the antibiotic Klavunamox include:
Amoxicillin trihydrate equivalent to Amoxicillin: 400mg content of clavulanate potassium equivalent to Clavulanic acid: 57mg content Combined with just enough excipients. 1.2. What are the uses of Klavunamox 400/57mg? With the main active ingredient is Amoxicillin - Penicillin group antibiotic, has bactericidal effect. Amoxicillin can bind to one or more bacterial proteins (PBPs) to inhibit bacterial cell wall synthesis. Klavunamox 400/57mg is used to treat some common Gram-negative infections in the body.
Amoxicillin has a lactam ring structure that is easily hydrolyzed by lactamases produced by some bacteria. Therefore, in combination with Clavulanic Acid, which is structurally similar to Amoxicillin, it will be able to bind better with lactamase enzymes, making Amoxicillin to be effective. Combining the effects of the two ingredients above helps Klavunamox 400/57mg to have a broader and more sustainable effect of killing bacteria.
The drug is indicated in the treatment of infections caused by susceptible strains in the following specific cases:
Respiratory tract infections: Upper respiratory tract infections: Sinusitis, tonsillitis, otitis media , other infections in the ear-nose-throat area. Lower respiratory tract infections: Acute and chronic bronchitis, pneumonia, empyema, lung abscess. Skin and soft tissue infections: Boils, abscesses, cellulitis, wound infections, intra-abdominal infections. Genitourinary tract infections: Cystitis, pyelonephritis, urethritis, pelvic infection, syphilis, gonorrhea. Other infections: Osteomyelitis. 1.3. Is Klavunamox a mild or severe antibiotic? Whether Klavunamox is a mild or severe antibiotic is a question many people ask because drug resistance is a concern when using antibiotics. Klavunamox is a combination of Amoxicillin and Clavulanic Acid, for a broad spectrum of antibacterial activity. However, the question of whether antibiotics are strong or mild is not yet standard, but the main thing is to consider the selection and use of antibiotics for the right principles, in accordance with treatment to bring safety and effectiveness to people. sick.

2. Usage of Klavunamox 400/57mg

2.1. How to take Klavunamox 400/57mg Shake well before use. The absorption of Klavunamox 400/57mg is best when taken immediately before meals. The duration of treatment should be appropriate to the indication and should not exceed 14 days without change. Fill the bottle with water up to the mark on the bottle, shake vigorously to mix the powder. 2.2. Dosage of Klavunamox 400/57mg Usual daily dose:
25/3.6 mg/kg body weight/day for mild to moderate infections (upper respiratory tract infections such as recurrent tonsillitis, respiratory tract infections). lower respiratory tract and skin and soft tissue infections). 45/6.4 mg/kg body weight/day for the treatment of more severe infections (upper respiratory tract infections such as bronchitis and urinary tract infections). The table below is a guide for children.
Children older than 2 years :

Children from 2 months to 2 years: Children under 2 years of age should take the dose according to weight.
Note: The above dosage is for reference only. The specific dose depends on the condition and the progression of the disease. To get the right dose, you need to consult your doctor or healthcare professional.
Also, take the medicine as soon as you remember it in case you forget it. However, if the interval between the next dose is too short, skip the missed dose and resume the dosing schedule. Do not take a double dose to make up for a missed dose.
On the other hand, despite excessive use of Klavunamox, the drug is still less likely to cause complications, because it is well tolerated even at high doses. However, in general, the acute reactions that will occur will depend on the hypersensitivity of the individual. The main risk is definitely hyperkalemia at very high doses because Clavulanic Acid is used as the potassium salt.
Hemodialysis can be used to remove drugs from the circulation. In the event of an emergency, call 911 immediately or go to the nearest local medical station.

3. Contraindications of the drug Klavunamox 400/57mg

Klavunamox is contraindicated in cases with a history of allergic reactions to the penicillin group.

4. Note when using Klavunamox 400/57mg

4.1. Precautions for use Serious and fatal anaphylaxis (hypersensitivity) have occasionally been reported in patients receiving penicillin. These reactions are more common in individuals with a history of hypersensitivity to penicillin and/or a history of hypersensitivity to various antigens. Patients with a history of hypersensitivity to penicillins and serious cross-reactions with cephalosporins have also been reported.
Therefore, before initiating Klavunamox 400/57mg, carefully investigate whether the patient has previously had hypersensitivity reactions to penicillins, cephalosporins or to other antigens.
When experiencing an allergic reaction, the drug must be stopped immediately and appropriate treatment measures taken. If severe anaphylactic reactions occur, emergency treatment with Epinephrine should be given immediately. Sometimes it is necessary to use oxygen, intravenous corticosteroids and open the airways.
Although the toxicity of penicillins is very low, regular assessment of organ function, such as kidney, liver, and hematopoietic function is required during long-term use. A high proportion of patients with pre-existing mononucleosis who received ampicillin have developed erythema multiforme. Therefore, penicillin antibiotics should not be used in patients with mononucleosis.
During treatment with Klavunamox 400/57mg, it should always be remembered that there is a possibility of superinfection with bacterial or fungal pathogens. If superinfection occurs (usually Pseudomonas or Candida), the drug should be discontinued and appropriate treatment instituted.
4.2. Ability to drive and use machines The drug is unlikely to affect the ability to drive and use machines.
4.3. Pregnancy and breast-feeding Pregnancy There is no clear evidence on the safety of Klavunamox 400/57 mg during pregnancy, so it should be used during pregnancy only when clearly needed.
Lactation Semi-synthetic penicillin antibiotics are excreted in milk. Caution should be exercised when Klavunamox 400/57 mg is administered to a nursing mother.

5. Side effects of the drug Klavunamox 400/57mg

Usually there are no too serious side effects after using Klavunamox 400/57 mg, patients may experience some unwanted symptoms such as: Headache, fatigue, feeling sad vomiting, vomiting, difficulty breathing,... On some patients may experience allergic conditions such as rash, hives
If you have any of the above signs or have abnormalities when using the drug, please contact the doctor. Notify your doctor for quick treatment and safety.

6. How to store Klavunamox 400/57mg

Klavunamox 400/57 mg is in the form of a solution, so it should be stored in a cool, dry place, out of direct sunlight and out of reach of children.

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