Uses of Ketovital

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1. What is Ketovital?

Ketovital drug belongs to the group of mineral and vitamin drugs, produced by Gia Nguyen Pharmaceutical Joint Stock Company. Ketovital is often prescribed by doctors for patients with impaired or impaired protein metabolism in the body, especially in those with chronic renal failure.
Ketovital brand-name drug is prepared in the form of film-coated tablets, with the main ingredients being amino acids and packaged in a box of 10 blisters x 10 tablets. Each Ketovital tablet contains the following specific ingredients:
α-Ketoleucin calcium 101mg. α-Ketoisoleucin calcium content 67mg. α-Hydroxymethionin calcium 59mg. α-Ketovalin calcium content 86mg. α-Ketophenylalanin calcium content 68mg. L-Threonine content 53mg. L-Tryptophan 23mg. L-Lysine Acetate 105mg. L-Tyrosine 30mg. L-Histidine hydrochloride monohydrate 38mg. In addition, Ketovital drug also includes other excipients just enough in one tablet, including: Polyethylene glycol 6000, Talc powder, Magnesium stearate, Crospovidone, Povidone K30, Colloidal silicon dioxide, Quinoline yellow, Titanium dioksid and Eudragit E100.

2. Indications and contraindications for the use of Ketovital

2.1. Indications for the use of Ketovital Ketovital is usually prescribed by doctors to prevent and treat disorders or impairment of protein metabolism in patients with chronic renal failure. Ketovital is also prescribed when a patient's diet does not provide the required amount of protein, protein levels are restricted to only 40g/day for adults. Normally, Ketovital drug will be used for patients with glomerular filtration rate (GFR) < 25ml/min.
2.2. Contraindications to the use of Ketovital The following are cases in which Ketovital should not be used without approval from a specialist:
Patients with hypersensitivity or atopic allergy to amino acids or any pharmaceutical any other substance in the drug. Ketovital is contraindicated in patients with hypercalcemia. Ketovital should not be used in patients with impaired amino acid metabolism. Consider when using Ketovital for patients with hereditary Phenylketonuria because the drug contains Phenylalanine.

3. Dosage and how to use Ketovital

3.1. Dosage of Ketovital The dosage of Ketovital will be determined by the doctor based on the patient's age and protein deficiency:
Ketovital dose for adults:
Ketovital dosage for humans Adults are usually divided into 3 times/day based on the patient's body weight, namely 1 tablet/5kg or 100mg/kg body weight. For example, a patient weighing 50kg can take 10 tablets per day in 3 divided doses (morning, noon and night). For adults weighing 70kg should take a dose of 4 - 8 tablets / time and divided 3 times / day. Before undergoing dialysis, patients should not exceed a dose of 40g protein/day. The exact dose of Ketovital will be determined based on the patient's degree of renal failure. During dialysis, the doctor will give specific indications about the protein intake rate for the patient.
Ketovital dose for children:
Ketovital is indicated for children over 3 years old. Dosage will be calculated based on the child's weight, namely 1 tablet / 5kg or 100mg / kg of body weight.
3.2. Instructions for proper use of the drug Ketovital Ketovital medicine is prepared in the form of tablets and taken orally. The ideal time to take Ketovital most effectively is right before a meal. This is because the absorption and metabolism of the amino acid components in Ketovital will be increased when taken with food. In addition, patients should also take Ketovital tablets whole, avoiding chewing, crushing or breaking tablets to achieve the highest therapeutic effect.
Ketovital can be used for a long time if the patient's glomerular filtration rate is less than 25ml / min and the amount of protein that the daily diet provides is less than 40g for an adult.

4. Possible effects when taking Ketovital

The majority of patients taking Ketovital are well tolerated, however certain cases have reported an increase in blood calcium levels during treatment with this drug. In that case, patients should reduce vitamin D intake and regularly monitor serum calcium levels.
If serum calcium levels remain elevated for a long time, the patient can consult a doctor about reducing the dose of Ketovital or any other calcium source, such as from the diet.
In addition to increased blood calcium levels, patients may also experience some other side effects that have not been mentioned. Ideally, if you notice that your body has an abnormal reaction after taking Ketovital, you should immediately notify a qualified doctor or pharmacist to refer to the appropriate remedy.

5. Things to note in the process of using Ketovital

5.1. What precautions should be taken while using Ketovital? When treating protein metabolism disorders with Ketovital, patients should note the following:
Always monitor serum calcium levels, and at the same time ensure adequate caloric needs for the body. Ketovital should be used with caution in patients with inherited metabolic disorders due to its active ingredient in phenylalanine. During the use of Ketovital in combination with aluminum hydroxide, the patient should closely monitor the serum phosphate concentration. Care should be taken when using the drug in combination with calcium-containing products to avoid increasing serum calcium levels. Ketovital should be used at least 2 hours away from the time of taking antibiotics such as Quinolone, Tetracycline or iron-containing drugs to avoid affecting the absorption of active ingredients by the body. Because Ketovital has the effect of improving blood urea, combining this drug with Aluminum Hydroxyd may cause unwanted side effects. There is currently no clinical information on the use of Ketovital in women who are planning to become pregnant, are pregnant or are breastfeeding. Therefore, these subjects should consult their doctor carefully and only use Ketovital when absolutely necessary. Ketovital does not affect the patient's ability to drive vehicles or machines. 5.2. What other medicines does Ketovital interact with? Treatment with Ketovital in combination with other calcium-containing drugs may increase serum calcium levels or increase the patient's existing medical conditions. Some drugs can form compounds that are difficult to dissolve with calcium, such as Quinolones, Tetracycline, Ciprofloxacin, Norfloxacin, iron-containing medicines or Flour. Ideally, you need to avoid concomitant use of Ketovital with these drugs to avoid adverse effects on the absorption of active ingredients by the body. If use is required, the time between drugs should be at least 2 hours apart.
When using Ketovital, there are signs of increased blood calcium levels, users may also experience arrhythmias and are sensitive to Glycosides acting on the heart.
The treatment with Aluminum Hydroxyd should be reduced because Ketovital has a good ability to improve uremia. In addition, patients also need to pay attention to reducing the level of phosphate in the blood.
5.3. How should Ketovital be stored? When storing Ketovital medicine, patients need to ensure a few things:
Store the medicine in a sealed package, avoid direct sunlight or high temperature. Avoid leaving Ketovital in a place where there is dust or mold, which affects the quality of the medicine. Store the medicine in a dry place, out of the reach of children or pets. Ketovital is recommended for use mainly for the prevention and treatment of impaired or dysfunctional protein metabolism in patients with chronic renal failure. To ensure effective treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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