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Iyafin medicine is often prescribed by doctors mainly to treat cases of allergic rhinitis or to help reverse other allergic symptoms. Patients need to follow the correct treatment plan for Iyafin to be most effective.
1. What is Iyafin?
Iyafin drug belongs to the group of drugs acting on the respiratory tract. Iyafin is often prescribed by doctors for nasal congestion, fever, headache, dry cough, cough with phlegm, sneezing, runny nose due to seasonal allergies, bronchitis or flu.
Currently, Iyafin is made in the form of tablets and packed in a box of 25 aluminum blisters x 4 tablets. Each Iyafin tablet contains the following active ingredients:
Main active ingredients: Chlorpheniramine maleate (2mg), Dextromethorphan HBr.H2O (15mg) and Glyceryl guaiacolate (100mg). Other excipients: Corn Starch, Lactose, Magnesium stearate, Microcrystalline Cellulose, Povidone K-30, Aerosil 200 (Colloidal silicon dioxide), Brilliant Blue (Brilliant blue) and Tartrazine Yellow (FD&C Yellow No. 5) .
2. What is the effect of Iyafin?
2.1 The effect of the drug Iyafin The active ingredient Chlorpheniramine maleate in the drug Iyafin belongs to the group of antihistamines with little sedative effect. Similar to other antihistamines, Chlorpheniramine maleate has the ability to inhibit the secretion of Acetylcholine, but this effect often affects each individual differently. According to research, the antihistamine effect of the active ingredient Chlorpheniramine maleate is due to the competitive blockade with H1 receptors of the effector cells.
After oral administration, chlorpheniramine maleate is well absorbed and present in plasma after only 30-60 minutes. The bioavailability of Chlorpheniramine maleate is quite low, reaching about 25-50%. Chlorpheniramine maleate is usually metabolized in the form of Desmethyl - Didesmethyl - Chlorpheniramine and is mainly excreted in the urine.
2.2 Indications for use of Iyafin Iyafin medicine is usually prescribed by doctors for the following cases:
Treatment of year-round allergic rhinitis or seasonal allergic rhinitis. Effective treatment of allergic symptoms such as urticaria, allergic conjunctivitis, vasomotor rhinitis caused by histamine, contact dermatitis, angioedema, food allergy, Quincke's edema, serum reaction, pruritus due to allergic reactions. measles/chickenpox, insect stings. 2.3 Contraindication to the use of Iyafin Avoid using Iyafin for the following cases without the prescription of a specialist:
Patients with a history of allergy or hypersensitivity to the active ingredient Chlorpheniramine maleate or any other ingredient another part of the drug. Contraindicated for patients being treated with Monoamine oxidase inhibitors, because when used together with Iyafin can cause serious reactions such as dizziness, high fever, brain bleeding or even death. Iyafin should not be used in patients with symptoms of an enlarged prostate. Avoid using Iyafin for people with angle-closure Glaucoma, bladder neck obstruction, peptic ulcer or pyloroduodenal obstruction. Iyafin is contraindicated for inpatients with chronic obstructive pulmonary disease, asthma, especially in acute attacks, because anticholinergic effects can thicken secretions and inhibit expectoration. Do not use Iyafin for people with chronic cough caused by bronchitis, asthma, smoking and emphysema. Contraindicated for pregnant women, infants, premature infants and lactating women.
3. Dosage and how to use Iyafin
3.1 Dosage of Iyafin Below is the dose of Iyafin recommended by the doctor for each specific patient, including:
Dose for children over 12 years old and adults: Take 1 tablet / time / day, up to 2 tablets/day. Dose for children from 6 to 12 years old: Take half a tablet / time / day. The above dosage is for reference only, patients should discuss with their doctor about their health status as well as age to get the appropriate dose of Iyafin.
3.2 Instructions for proper use of Iyafin Iyafin medicine is made in the form of tablets, so patients can take the drug orally at the time before or after meals. During treatment with Iyafin, patients need to strictly follow the doctor's regulations on drug dosage, avoid arbitrarily changing or adjusting the dose to prevent dangerous risks to health.
Besides, Iyafin medicine needs to be used regularly and on schedule or time to promote the most optimal effect. Patients need to limit the consumption of greasy foods in their daily diet, at the same time increase the vegetables and fruits and reduce the drinks containing gas, alcohol or stimulants such as tobacco in the diet. during treatment with Iyafin. In addition, patients should also combine exercise with moderate intensity to help improve resistance as well as the immune system, helping to shorten the treatment time.
4. Possible side effects when using Iyafin
Iyafin medicine may cause some side effects for patients during treatment, including:
Sedative effects: Light drowsiness, deep sleep, dizziness, dry mouth or irritation when treatment is interrupted. interval. Common side effects: Dry mouth, sedation or somnolence. Rare side effects: Nausea, dizziness. Other side effects: Diarrhea, constipation, nausea, vomiting, anorexia, abdominal pain, sinus arrhythmias, extrasystoles, arrhythmias, tachycardia, α-adrenergic blockade drop in blood pressure, increased blood pressure or phlegm when taking large doses of the drug. In case of occurrence of any of the side effects mentioned above, the patient should stop taking the drug and inform the doctor as soon as possible so that it can be treated.
5. Things to note and caution when using Iyafin
5.1 What precautions should be taken while using Iyafin? Before deciding to use Iyafin, patients should inform their doctor if they are in the following conditions:
Pregnant, nursing. Are allergic to any of the ingredients in Iyafin. Are taking other medications. Are taking or have used a monoamine oxidase inhibitor (MAO) antidepressant within the previous 14 days. Intending to use Iyafin for children and the elderly. Current or history of medical conditions such as asthma, urinary retention, cardiac arrhythmias, chronic obstructive pulmonary disease, gastrointestinal obstruction, bladder neck obstruction, angle-closure glaucoma, cardiovascular disease, urinary In addition, in the process of using Iyafin, the patient also needs to be cautious of the following:
Because Iyafin has anti-acetylcholine effect, so the patient may be at risk of urinary retention. when taking medication. The sedative effect of the active ingredient Chlorpheniramine in the drug will be significantly increased if the patient uses the drug while drinking alcohol or taking some other sedatives. There is a risk of respiratory complications, respiratory arrest or respiratory failure. This is especially detrimental for patients with obstructive pulmonary disease or in young children. Therefore, Iyafin should be used with caution in case of chronic lung disease, shortness of breath or shortness of breath. Iyafin has the potential to cause symptoms such as dizziness, somnolence, dizziness, blurred vision or psychomotor impairment in some patients, and has the potential to affect the ability to drive, do working at height as well as operating machinery. Therefore, these subjects need to be very careful during treatment with Iyafin. 5.2 What drugs can Iyafin interact with? According to research, the drug Iyafin may have an interaction reaction when combined with the following drugs:
Monoamine oxidase inhibitors (MAOI) when combined with Dextromethorphan HBr.H2O can cause patients to muscle tremors, high fever, nausea, or coma. CNS depressants, when used with the active ingredient chlorpheniramine maleate, may cause additive effects, such as sedation or drowsiness. Avoid combining Chlorpheniramine maleate with alcohol, sedatives, barbiturates, hypnotics or other H1 blockers. Increases the CNS depressant and anticholinergic effects of chlorpheniramine maleate when co-administered with monoamine oxidase inhibitors. Do not take chlorpheniramine maleate with other anticholinergics, such as phenothiazines or tricyclic antidepressants. Knowing the information about the drug Iyafin will help the process of using the drug to achieve high efficiency in the treatment process. In addition, it also helps patients reduce certain risks.
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