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Indform 500 belongs to the group of hormonal drugs, used in the treatment of type 2 diabetes (non-insulin dependent diabetes) when dietary and lifestyle changes have been made but uncontrolled blood sugar levels. To learn more about Indform 500 you can refer to the article below.
1. What is Indform 500?
Indform 500 drug has the main ingredient Metformin HCl, 500mg content along with other active ingredients and excipients just enough. The drug is absorbed very quickly from the gastrointestinal tract and exerts its maximum effect after 2 hours of use. Metformin has been shown to decrease hepatic glucose synthesis, inhibit intestinal glucose absorption, increase insulin sensitivity in peripheral tissues, and stimulate cellular glucose utilization. Therefore, the drug is effective in reducing fasting and postprandial blood glucose concentrations in patients with type 2 diabetes, but rarely causes severe hypoglycemia when used alone at the recommended dose. In addition, Metformin also has the effect of reducing blood lipid synthesis, lowering LDL-C levels, increasing HDL-C levels, the drug does not increase weight, so it is very suitable for overweight people.
2. Uses of Indform 500
Indform 500 is used in the treatment of type 2 diabetes (non-insulin dependent diabetes) when dietary and lifestyle changes have not been controlled. It can be used alone or in combination with other hypoglycemic agents depending on the condition of the patient.
3. Dosage - how to use Indform 500
Dosage:
For adults: The starting dose is usually 500mg/time/day. If blood glucose levels are not controlled, the dose can be increased gradually up to a maximum of 2000 mg/time/day. If target blood glucose levels are still not achieved with a dose of 2000 mg once daily, a dose of 1000 mg twice daily should be tried. The starting dose in people who were using the rapid-release metformin switched to the delayed-release form was about the same. Patients already on a dose of 2000 mg/day need not be converted to a delayed-release form of Metformin. If you are taking another antidiabetic agent and you want to switch to Metformin, you should stop using that drug and use Indform 500 at the recommended dose above. In treatment, metformin and insulin can be combined to achieve better blood sugar control. The starting dose of Metformin is 500mg/time/day, and the insulin dose will be adjusted depending on the patient's blood glucose levels. For the elderly, debilitated body : The starting dose should be cautious depending on the patient's renal function status, should not be treated to the maximum dose. When the maximum dose of metformin is not reached for 4 weeks when the maximum dose of metformin is not reached, a sulfonylurea drug should be combined. When the patient still does not respond to the 2 drug combination therapy with the maximum dose for 1 to 3 months, the oral hypoglycemic agents should usually be discontinued and parenteral insulin therapy started. Usage: should be taken with meals to reduce side effects on the patient's gastrointestinal tract.
4. Contraindications of Indform 500
Hypersensitivity to metformin or any other components of the drug The patient is in a state of severe infection, sepsis, metabolic acidosis. People with impaired liver and kidney function. People who are suffering from congestive heart failure, acute myocardial infarction, respiratory failure When performing surgery or X-ray with contrast injection, the drug should be stopped because when used simultaneously with these substances can cause affect kidney function. Alcoholics, malnutrition, children under 10 years old should not use this medicine.
5. Signs to know when using Indform 500 . overdose
When overdose of Indform 500 can cause symptoms such as:
Abdominal pain, diarrhea Fast or shallow breathing Feeling chills Feeling unusually sleepy When taking Indform 500 overdose, you need to tell your doctor right away. doctor or pharmacist for advice and support. If there are other serious abnormal symptoms, you should immediately contact the 115 emergency center for help or immediately go to the nearest medical facility for timely treatment.
6. Interactions with Indform 500
Do not drink alcohol while being treated with Metformin, as it may increase the risk of lactic acidosis.
When used concurrently with drugs that cause hyperglycemia such as thiazide diuretics, corticosteroids... can reduce the effectiveness of blood sugar control.
Metformin has the potential to interact with drugs such as amiloride, digoxin, morphine, procainamide, quinidine, ranitidine, triamterene, trimethoprim and vancomycin.
7. Side effects of Indform 500
Like other drugs, Indform can cause unwanted effects, although not everyone experiences such as:
Digestive disorders: abdominal pain, diarrhea, constipation, nausea, vomiting, metallic taste in the mouth. On the skin: red, itchy skin, rash, urticaria. Other reactions such as increased liver enzymes, headache, dizziness, dizziness, decreased absorption of folic acid and Vitamin B12 with prolonged use. Lactic acidosis can also be encountered when taking the drug, which can be life-threatening. During use, if you see unusual or unwanted symptoms other than the above symptoms, you should immediately notify the treating doctor/medical staff for advice and timely treatment.
8. Notes and cautions while taking Indform 500
Patients should take Indform with meals to reduce unwanted effects on the gastrointestinal tract. When using the drug, it is necessary to periodically test blood glucose levels to determine the minimum effective dose of Indform and adjust the drug dose when necessary. While being treated with Indform 500, patients still have to adhere to a reasonable diet and lifestyle to achieve effective treatment. People with impaired renal function, when treated with Indform, there is a high risk of lactic acid accumulation and metabolic acidosis. When preparing for surgery or X-rays with contrast injection, the drug should be stopped 2-3 days before and within 2 days after the scan, and only restarted when the kidney function has returned. normal. The drug can reduce the absorption of vitamins B9 and B12, causing megaloblastic anemia. When combined with Indform with other hypoglycemic agents can cause hypoglycemia, so caution should be exercised. Use with caution in pregnant and lactating women. Above is some information about Indform 500 medicine, if you need advice or have any questions, please consult a qualified doctor or pharmacist for answers.
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