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Huygesic Fort is used in the treatment of pain with the main ingredient being Paracetamol. The following article would like to provide readers with the content about the uses, usage and notes when using Huygesic Fort to achieve the highest efficiency.
1. What is Huygesic Fort?
Huygesic Fort belongs to the group of pain relievers-fever-reducing, non-steroidal anti-inflammatory drugs, drugs to treat Gout and bone and joint diseases, with the main effect to treat moderate to severe pain. Huygesic Fort contains Paracetamol 325 mg and Tramadol Hydrochloride 37.5 mg in the form of hard capsules.
2. What are the uses of Huygesic Fort?
Huygesic Fort has the following effects:
Supports the treatment of moderate to severe pain such as: toothache, headache, muscle pain, menstrual pain in women, pain after surgery... Article Treatment of colds and fevers such as headache, cough, runny nose, stuffy nose...
3. Contraindications to taking Huygesic Fort
Because Huygesic Fort's safety in infants and children has not been studied, it is not recommended to use it in nursing women.
4. Dosage and usage of Huygesic Fort
Huygesic Fort is used orally, applying different doses to each group of subjects, specifically.
Adults, children > 12 years: The maximum dose is from 1-2 tablets in a period of 4 to 6 hours and do not use more than 8 Huygesic Fort tablets in 1 day. Children < 12 years: In children, the safety and effectiveness of the drug have not been clearly studied. It is recommended for this group of subjects to use the drug in the form of syrup for safety. Patients need to apply the correct dose of the drug listed on the Huygesic Fort drug instruction sheet or according to the dose prescribed by the pharmacist or doctor.
5. What to do in case of missed dose or overdose of Huygesic Fort?
If a dose of Huygesic Fort is forgotten, the patient should take it as soon as possible. However, if it is almost time for the next dose, the patient should skip that dose and take the next dose as usual. Never arbitrarily make up the previous dose for the next dose, so consult your doctor, pharmacist if you forget. dose for maximum safety and effectiveness.
In case of overdose of Huygesic Fort: It should be noted that clinical manifestations of Huygesic Fort overdose may coincide with signs and symptoms of poisoning with Paracetamol, Tramadol or both.
When using Tramadol in excess of prescribed will cause quite serious consequences such as: respiratory failure, coma, convulsions, severe cardiac arrest and death. In some patients, high doses of Paracetamol can be toxic to the liver. Attention should be paid to the symptoms that appear early when the liver is damaged by paracetamol overdose such as: Strong irritation to the gastrointestinal tract (loss of appetite, nausea, vomiting); uncomfortable body, pale face, sweating a lot. Symptoms of hepatotoxicity may appear 48-72 hours after the patient takes the drug. It is necessary to perform the exact dose of Huygesic Fortin listed on the package, the drug instruction sheet or as directed by the doctor or pharmacist. Patients do not arbitrarily calculate, apply and change the dose of the drug.
6. Drug interactions of Huygesic Fort
When combined with Huygesic Fort with some of the following drugs may cause drug interactions such as:
Use with Serotonin reuptake inhibitors and MAO inhibitors: Using Huygesic Fort simultaneously with drugs This has a high risk of unwanted side effects including seizures and Serotonin syndrome. Use with Carbamazepine: The combination of Tramadol Hydrochloride with Carbamazepine will increase the metabolism of Tramadol. At the same time, the analgesic effect of Tramadol in the drug may be reduced in patients taking Carbamazepine. Use with Quinidine: When Huygesic Fort is used with this group, the Tramadol component is converted to M1- which is an active metabolite of CYP2D6 inhibitors. Concomitant use of Quinidine and Tramadol will increase the concentration of Tramadol. The clinical outcome of this interaction is available but is not yet clear. Use with substances of the Warfarin class: As a medical rule, periodic evaluation of the extracoagulation time is necessary when used in combination with these drugs due to the recognition of the INR (international normalized ratio - international normalized ratio). ) for increased results in some patients. Use with CYP2D6 Inhibitors: In vitro studies of Huygesic Fort drug interaction on human liver microsomes showed that when co-administered with CYP2D6 inhibitors (Fluoxetine, Paroxetine and Amitriptyline) Tramadol metabolism may be more limited. Use with Cimetidine: When used in combination between Tramadol and Cimetidine, clinically, it did not change the pharmacokinetics of Tramadol.
7. What side effects does Huygesic Fort cause?
During the use of Huygesic Fort, patients may experience some unwanted side effects such as:
On the central nervous system such as: Headache, drowsiness, dizziness, dizziness, loss of balance, pain severe migraine, convulsions, muscle tension, involuntary muscle contractions, paresthesia. Digestive system with manifestations: Vomiting, nausea, dry mouth, digestive disorders, black stools due to gastrointestinal bleeding, tongue edema, difficulty swallowing. Weak body, fatigue and strong emotions. Psychiatric effects: Loss of appetite, long anxiety, trouble sleeping, decreased memory, restlessness, Skin, skin-dependent parts: Itching, rash, increased sweat gland secretion. Whole body: Chills, syncope, withdrawal syndrome. Cardiovascular disorders: Palpitations, hypotension, hypertension, arrhythmia, tachycardia. Tinnitus. Abnormal liver function. Weight loss. Psychiatric disorders: drug abuse, forgetfulness, loss of consciousness, nightmares, depression, mood instability, hallucinations, impotence, abnormal ideas, etc.
8. Precautions when using Huygesic Fort
Caution should be used when using Huygesic Fort because there is a risk of convulsions when tramadol is used concurrently with Opioids, SSRIs (serotonin reuptake inhibitors), MAOIs, TCAs (tricyclic compounds), sedatives psychotropic drugs or drugs that lower the seizure threshold; or in patients with epilepsy, in patients with a history of seizures, or in patients at risk for seizures. Use caution when using the drug because there is a risk of respiratory failure in patients at risk of respiratory failure; Using drugs with alcohol, anesthetics, anesthetics and taking high doses of Tramadol, CNS depressants (hypnotics, tranquilizers, Opioids) Caution should be used in patients with increased intracranial pressure. or head injury. Use with caution in patients who are addicted to opiates because it can cause relapse. Use with caution in chronic alcoholics because of the risk of hepatotoxicity. When an overdose of Tramadol is used, Naloxone may increase the risk of convulsions. For patients with creatinine clearance < 30 ml/min, it is recommended that the dose of Paracetamol not exceed 2 tablets every 12 hours. Paracetamol should be used with caution in patients with severe hepatic impairment. Do not exceed the indicated dose of Huygesic Fort. Do not take the drug with other drugs containing the active ingredients Paracetamol or Tramadol. In addition, the subjects that need to be noted before taking Huygesic Fort: Elderly people, children <15 years old, pregnant women, lactating women, people with a history of allergic hypersensitivity to any drug. any substance in the drug, patients with liver / kidney failure, patients with myasthenia gravis, hepatic coma, stomach ulcers. Consider and consult your doctor or pharmacist before taking Paracetamol. Because even though drugs have been tested, there are still risks when using them. Mothers need to carefully weigh the benefits and harms for mother and baby. Do not arbitrarily use Huygesic Fort without carefully reading the instructions for use and instructions of the doctor to protect the mother and baby.
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