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Histapast is an antihistamine that helps relieve the symptoms of allergies. Let's learn about the uses and notes when using Histapas through the article below.1. Uses of the drug Histapas
Histapast medicine 5mg has the main ingredient is Levocetirizine dihydrochloride 5mg and excipients (wheat starch, microcrystalline cellulose, talcum powder, magnesium siearal, colloidal silicon dioxide, povidone, gelatin). The drug is in the form of hard capsules.
Levocetirizine is a drug with antagonistic effects and is effective at peripheral histamine H1. Binding studies for levocetirizine showed a 2-fold higher affinity for histamine H1 in humans than cetirizine. Efficacy studies in volunteers have demonstrated that at half the dose, Levocetirizine is as active as Cetirizine (an isomer of Levocetirizine), as an antihistamine in both the skin and the nose. That is, with a lower dose but equally effective as drugs in the same class, must be used at twice the dose, thus reducing the side effects of the drug.
2. Indications and contraindications of the drug Histapas
Histapast 5mg is indicated in the following cases:
Seasonal and year-round allergic rhinitis causing symptoms such as sneezing, runny nose, itchy nose and cough. Idiopathic urticaria or urticaria with a cause. Allergic conjunctivitis with red/itchy/watery eyes... Do not use the drug in the following cases:
Hypersensitivity to Levocetirizine, Cetirizine, Hydroxyzin or to other components of the drug. Patients with end-stage renal failure have creatinine clearance less than 10ml/min. Children under 6 years old.
3. Dosage and usage of Histapast
How to use: Take the drug orally on an empty stomach or with food.
Dosage:
Adults and children over 6 years old: The recommended dose is 1 tablet per day (Levocetirizine dihydrochloride 5mg). Patients with renal impairment need to adjust the dose according to the patient's renal function: Creatinine clearance (ml/min): From 50-80, use at a dose of 2.5mg once a day; Creatinine clearance (ml/min): From 30 to 50, use at a dose of 2.5mg per day; Creatinine clearance (ml/min): From 10-30 use 2.5mg twice weekly or 3 to 4 days once 2.5mg.
4. Undesirable effects of the drug Histapas
In general, Levocetirizine when used is generally well tolerated. However, it can also cause some undesirable effects that rarely occur such as: Feeling dry mouth, headache, drowsiness, fatigue, migraine, rhinitis, sore throat, abdominal pain.
If there are side effects of the drug, it is necessary to notify the doctor for appropriate treatment.
5. Notes when using Histapas
Precautions for use:
Dosage should be reduced in elderly patients (over 65 years) if renal function is impaired; Use caution when co-administering Levocetirizine with alcohol or CNS depressants; Use in pregnancy and lactation: The safety of Levocetirizine during pregnancy has not been established. Therefore, caution should be exercised when using this drug in pregnant women. The drug is likely to be excreted in breast milk and should not be used in nursing women. Effects on ability to drive and use machines: The drug may cause drowsiness and blurred vision, so use caution when driving or operating machinery. Especially in the first time when using the drug, it is necessary to monitor for abnormal signs. Overdose: May cause symptoms such as somnolence in adults and children. There is no specific antidote for Levocetirizine yet. If overdose occurs, treat mainly symptomatic and supportive. Gastric lavage may be considered if the duration of overdose is short. Elimination of Levocetirizine by dialysis is ineffective.
Storage: Store in a dry place, the temperature is below 30 ° C. Keep out of reach of children. Do not use when the capsule shell is torn, past the expiry date.
Above is information about what Histapast is, its uses and notes when using it. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Histapas medicine exactly as directed by your doctor.
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