Uses of Heavarotin 10

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1. What is Heavarotin 10?

Heavarotin 10 belongs to the group of cardiovascular drugs, is made in the form of film-coated tablets and packed in boxes of 3 blisters x 10 tablets, manufactured at Mepro Pharmaceuticals Pvt. Ltd. - INDIA.
Heavarotin 10 contains the main ingredient Rosuvastatin (in the form of Rosuvastatin Calcium) with a concentration of 10mg and other excipients such as: Anhydrous Lactose (DCL-15), Calcium Phosphate (Tribasic Calcium Phosphate), Crospovidone, Microcrystalline Cellulose. Sancel PH 102), Magnesium Stearate, Hypromellose 6CP, Titanium Dioxide, Purified Talc, Propylene Glycol.

2. Indications for use of Heavarotin 10

Heavarotin 10 is used in the following cases:
Treatment for patients with high cholesterol in the blood (type IIa of the heterozygous group). Mixed dyslipidemia (type Tb). Homozygous familial hypercholesterolemia.

3. Dosage - How to take Heavarotin 10

The first dose is from 5-10mg Rosuvastatin, 1 time a day. If necessary, the dose can be adjusted every 4 weeks, the dose of 40mg Rosuvastatin should only be used when severe hypercholesterolemia and high risk of cardiovascular disease is not achieved at the dose of 20mg Rosuvastatin. Accordingly, patients need to be monitored regularly.
Note:
In patients with a history of liver disease, caution should be taken when the patient has factors such as hypothyroidism, rhabdomyolysis such as kidney failure, personal or family history of hereditary muscle disease, alcoholism , history of myotoxicity due to other HMG-CoA reductase inhibitors or fibrates, patients over 70 years of age, concomitant use of fibrates and conditions causing increased drug levels in the blood.
Discontinue Heavarotin 10 if CK > 5 x ULN or severe muscle symptoms. Should not be used in the presence of sepsis, hypotension, major surgery, endocrinology, trauma, electrolyte disturbances, severe metabolism, uncontrolled convulsions.

4. Contraindications to the use of Heavarotin 10

Heavarotin 10 should not be used in the following cases:
Patients with hypersensitivity or history of allergy to Rosuvastatin or to any ingredient in the drug. Patients with active liver disease, when transaminase elevations more than 3 times the upper limit of normal including unexplained persistent elevations in serum transaminases. The patient has severe renal failure. Muscle disease. People who are taking the drug cyclosporin. People who are pregnant or breastfeeding Children

5. Heavarotin 10 drug interactions

The drug Heavarotin 10 when combined with some drugs can occur drug interactions such as:
Co-administration of Cyclosporin with Rosuvastatin can increase the mean AUC value of Rosuvastatin 7 times in the following patients. healthy volunteers. However, the combination of Cyclosporin and Rosuvastatin did not affect the plasma concentrations of Cyclosporin. Gemfibrozil, lipid-lowering agents in combination with Rosuvastatin will increase the Cmax and AUC of Rosuvastatin twofold. Antacids containing aluminum and magnesium hydroxide reduce plasma concentrations of Rosuvastatin by almost 50% when used in combination. Erythromycin in combination with Rosuvastatin reduces the AUC and Cmax of Rosuvastatin by 20% and 30% when used in combination. Concomitant use of Rosuvastatin with high-dose fibrate-lowering drugs, Gemfibrozil, Niacin (> 1g/day), Colchicin will increase the risk of muscle damage. Concomitant use of Rosuvastatin with lipid-lowering agents of the statin class with drugs for the treatment of HIV and hepatitis C virus (HCV) may increase the risk of muscle damage, most seriously rhabdomyolysis, kidney failure lead to kidney failure and possibly death.

6. What side effects does Heavarotin 10 cause?

During the use of Heavarotin 10, patients may experience some side effects as follows:
Common:
Headache, dizziness Digestive disorders such as nausea, vomiting, constipation, abdominal pain Subcutaneous and subcutaneous soft tissue disorders. Uncommon:
Itching, rash, urticaria Bone and connective tissue disorders such as myalgia, musculoskeletal disorders Rare:
Bone pain, muscle weakness, cramps, arthralgia, muscle damage such as atrophy , myositis. There are also some other undesirable effects when using Heavarotin 10 such as:
Typical cognitive decline is confusion, memory loss,... Increased blood sugar Increased HbAlc

7. Recommendations and cautions when using Heavarotin 10

Patients should have liver enzyme tests before treatment with Satin, because the drug can lower blood lipids and increase serum transaminases. Heavarotin 10 should be used with caution in patients with alcohol abuse and liver disease. Care should be taken when administering Rosuvastatin to patients with risk factors for muscle damage, because Rosuvastatin carries a risk of causing adverse muscle reactions such as muscle atrophy, myositis, especially in patients with risk factors such as patients over 65 years old, patients with uncontrolled hypothyroidism, patients with kidney disease. Close monitoring of adverse reactions is required during the use of Rosuvastatin. Patients should immediately report to their doctor all symptoms such as fever, muscle aches, fatigue, dark urine, nausea/vomiting while taking Rosuvastatin. The risk of myopathy during treatment with Heavarotin 10 is increased with concomitant use of Cyclosporine. There have been reports of Rosuvastatin causing harm to the fetus when administered to a pregnant woman. Therefore, do not use the drug for women who are planning to become pregnant and become pregnant. Because of the potential for adverse reactions in the nursing infant, Heavarotin 10 should not be used while breastfeeding or discontinue nursing when it is absolutely necessary. Heavarotin 10 drug with the main ingredient is Rosuvastatin and is used in the treatment of high cholesterol in the blood, mixed dyslipidemia. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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