Grippostad C - a pain reliever and fever reducer is used as prescribed in certain cases. To use the drug safely, let’s learn more about Grippostad C, its uses, how to use it, dosage, warnings, etc., below.
1. What is Grippostad C?
Grippostad C – belongs to the group of prescription drugs, categorized as pain relievers, fever reducers, and non-steroidal anti-inflammatory drugs. The main ingredients of Grippostad C include:
- Paracetamol;
- Ascorbic acid;
- Caffeine;
The drug is packaged in a box containing 2 blister packs, each with 10 hard capsules. The capsule heads are yellow, the bodies are white, with the words "STADA" printed on both parts, containing white powdered medication.
2. Uses of Grippostad C
What is Grippostad C? This medicine contains ingredients that help relieve pain and reduce fever. The specific effects of Grippostad C are based on its components:
2.1 Paracetamol
This is an active metabolite of phenacetin – a pain reliever and fever reducer that can substitute aspirin. However, this ingredient does not treat inflammation. At equivalent gram-based dosages, paracetamol has pain-relieving and fever-reducing effects similar to aspirin.
Grippostad C acts on the hypothalamus, helping lower body temperature and promoting heat dissipation through vasodilation and increased peripheral blood flow. Paracetamol does not affect platelets or bleeding time.
Paracetamol is absorbed through the gastrointestinal tract, reaching peak plasma levels within 30 minutes to 1 hour after ingestion.
2.2 Ascorbic Acid
This is a substance essential for collagen formation, aiding in tissue repair and participating in various oxidation-reduction reactions in the body. Ascorbic acid in Grippostad C plays a role in the metabolism of phenylamine, tyrosine, folic acid,... and several drug-metabolizing enzymes.
Ascorbic acid is easily absorbed after oral administration and is excreted in urine in unchanged form.
2.3 Caffeine
This is a xanthine derivative that stimulates the central nervous system, reduces fatigue, and enhances mental activity. Additionally, this ingredient increases the pain-relieving effects of paracetamol and counterbalances the central nervous system effects of chlorpheniramine.
Caffeine is absorbed after ingestion and distributed throughout the body, with a half-life of 3–7 hours.
2.4 Chlorpheniramine maleate
This is an antihistamine with mild sedative effects. Like most antihistamines, chlorpheniramine also has anticholinergic side effects, though these vary between individuals. Its antihistaminic action works by competitively blocking H receptors in target cells.
Chlorpheniramine maleate is well absorbed, appears in plasma 30–60 minutes after ingestion, and is excreted in urine as either unchanged or metabolized forms. In general, the purpose of Grippostad C is to relieve pain and reduce fever, as prescribed by a doctor.
3. Indications for Grippostad C
Grippostad C is indicated for cases of:
- Headache
- Pain associated with the common cold, accompanied by symptoms such as cough, runny nose...
To ensure safe use of Grippostad C, follow your doctor’s instructions.
4. Dosage - how to use Grippostad C
Grippostad C is taken orally with water. Do not take it continuously for a long period or use high doses without medical advice.
The recommended dosage of Grippostad C by the manufacturer is for adults to take 2 capsules per dose, 3 times a day. Additionally, dosages may be adjusted according to the doctor’s prescription and guidance.
5. Contraindications of Grippostad C
What is Grippostad C? It belongs to the group of pain relievers and fever reducers. However, its use requires a prescription. Certain individuals should not use Grippostad C, including those with:
- A history of hypersensitivity or allergy to the ingredients of Grippostad C
- Glucose-6-phosphate dehydrogenase deficiency
- Kidney stones
- Hyperoxaluria
- Oxalate metabolism disorders
- Congenital hemolytic anemia
- Acute asthma attacks
- Prostate enlargement
- Bladder neck obstruction
- Stomach ulcers
- Children under 12 years old
These individuals should not use Grippostad C to ensure safety.
6. Precautions and Warnings for Using Grippostad C
The manufacturer provides several precautions and warnings for safe use of Grippostad C, including:
- Use with caution in individuals with liver or kidney dysfunction, kidney stones, anemia, etc.
- Only use Grippostad C under the prescription and supervision of medical professionals.
- People with ulcerative colitis or hyperthyroidism should use the drug only under guidance.
- Do not use in individuals with rare genetic disorders.
- Warn patients about the possibility of severe skin reactions caused by paracetamol.
Follow the precautions and warnings provided by the manufacturer to ensure safe use of Grippostad C.
7. Interactions of Grippostad C
Grippostad C may cause drug interactions:
Paracetamol, an ingredient in Grippostad C, may interact with:
- Oral anticoagulants (should not be used together).
- Phenothiazines.
- Alcohol.
- Anticonvulsants.
8. Notes when using Grippostad C
Grippostad C should be used with caution in:
8.1 Pregnant women
Use Grippostad C with caution during pregnancy, especially in the last trimester, as it may cause serious reactions such as seizures in newborns.
8.2 Breastfeeding
Grippostad C contains chlorpheniramine, which is excreted in breast milk. Antihistamines can cause severe reactions in breastfeeding infants. Additionally, caffeine is also excreted in breast milk and may affect the infant's respiratory system. Therefore, Grippostad C should not be used by breastfeeding women.
8.3 Driving, operating machinery
People in this group should use Grippostad C with caution, as it may cause dizziness, impaired psychomotor functions, and affect work performance.
9. Side effects of Grippostad C
Grippostad C may cause side effects including:
- Thrombocytopenia, leukopenia, neutropenia, agranulocytosis
- Angioedema, rash
- Kidney toxicity with prolonged use
- Belching
- Nausea and vomiting
- Drowsiness
- Insomnia
- Delirium
- Nervousness
- Dry mouth
These side effects can be complex. If any occur, inform your doctor immediately for appropriate management.
What does Grippostad C do? It reduces pain and fever and is used as prescribed and dispensed by a doctor. Grippostad C may cause complex side effects and drug interactions. Exercise caution and inform your doctor about any relevant information (medical history, other medications, etc.) to ensure safe use.
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