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Thanks to the active ingredient Gliclazide, Glizym has a hypoglycemic effect in people with type 2 diabetes and is not dependent on insulin. Note that Glizym is not for pregnant women and children.
1. Uses of the drug Glizym
Glizym (or Glizym-M) belongs to the group of drugs to treat diabetes, with the ingredients Metformin Hydrochloride 500mg and Gliclazide 80mg. The specific effects of each active ingredient are known as follows:
Gliclazide: Belongs to the sulfonylurea group, which works to increase insulin secretion in both phase 1 and 2. Active ingredient Gliclazide increases insulin secretion significantly to absorb glucose after meals or when drinking sugar. Metformin: Belongs to the group of biguanides, effective in reducing high blood sugar in people with diabetes. Glizym is made in the form of tablets, indicated in the treatment of type 2 diabetes in patients who are not insulin dependent, with or without obesity. The drug is not used to interfere with blood sugar regulation through eating, weight loss, exercise, ...
The effect of the drug lasts for 12-24 hours. With a short effect, Glizym is suitable for elderly patients because other drugs are prone to hypoglycaemia.
Glizym M được ứng dụng trong điều trị bệnh tiểu đường
2. Usage and dosage of Glizym
Glizym-M is used orally with the recommended dosage as follows:
Starting dose: 30mg/day (equivalent to 1 tablet/day); Maximum dosage (if needed): 120mg/day (equivalent to 4 tablets/day); Dosage is adjusted according to the patient's response. The initial dose of 30 mg/day may be maintained if glycemic control is achieved. In case of uncontrolled blood sugar, it can be increased gradually, from 2 tablets (2x30mg) to 3 tablets (3x30mg) and 4 tablets (4x30mg), each dose increase should be spaced about 1 month apart. If after 2 weeks of treatment with Glizym but blood sugar does not decrease, the dose can be increased at the end of the 2nd week after taking the drug.
In case of overdose, the drug can cause hypoglycemia and at that time the patient should be treated with gastric lavage, adjustment, and continuous blood glucose monitoring until normal.
3. Side effects of the drug Glizym-M
Glizym medicine can cause some unwanted effects such as:
Digestive disorders with manifestations such as belching, metallic taste in the mouth, nausea, vomiting, diarrhea, boredom or increased appetite ; Itching, skin rash, skin more sensitive to light, flushed face; Mild hypoglycemia; Some other changes to liver enzymes, cholestasis, jaundice, hepatitis, decreased white blood cells and platelets, agranulocytosis, aplastic anemia, hemolytic anemia, dermatitis, exfoliative skin, rash red, Stevens-Johnson syndrome.
Glizym-M có thể gây ra một số tác dụng phụ khi sử dụng
4. Some notes when using Glizym-M
When using Glizym, it should be noted:
Glizym is not used to treat diabetes in children, pregnant and lactating women, people who are allergic to the drug's ingredients; People with type 2 diabetes who have just undergone surgery, have an infection or are in the stage of ketoacidosis, should not take Glizym; Although gliclazide is inactivated in the liver and can be used in patients with renal impairment, careful blood glucose monitoring is required. In particular, do not use Glizym in people with severe liver or kidney failure. Glizym may interact with drugs for diabetes, birth control, diuretics, thyroid, laxatives, Phenothiazine derivatives, Phenylbutazone, Salicylates, Sulfonamides, Coumarin, Clofibrat, Chloramphenicol, Cimetidine, Disopyramid, Miconazole, Tetracycline. In addition to taking the drug Glizym, patients need to combine and pay attention to their lifestyle and daily activities as follows:
Eat scientifically, increase fruits and vegetables, and limit starchy and greasy foods. ; Avoid using stimulants such as alcohol, beer, tobacco; Do not stay up too late (after 23 hours), exercise regularly; Use sugar for people with diabetes. The use of Glizym is to help lower blood sugar in people with type 2 diabetes. Besides taking drugs, to control blood sugar effectively, patients need to combine eating and exercising appropriately.
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