This is an automatically translated article.
Glanax 1.5g is used when the infection is severe. The drug is sold by prescription and administered by injection. The cases that need to be used or how to use Glanax will be prescribed and guided by the doctor.
1. What is Glanax 1.5g?
Glanax 1.5g is an injectable preparation of Cefuroxime, a semi-synthetic broad-spectrum antibiotic of the second generation Cephalosporin group.
The drug is a product of Glomed Pharmaceutical Joint Stock Company. Glanax is packaged in a vial and contains Cefuroxime sodium sterile powder equivalent to 1.5g Cefuroxime.
2. Uses of Glanax 1.5g
The antibiotic Cefuroxime in Glanax works by the same mechanism as other Cephalosporins, that is, it inhibits bacterial cell wall synthesis. The drug is active against most Gram-positive and Gram-negative bacteria.
Compared with 1st generation cephalosporin antibiotics, the drug has better in vitro activity against Gram (-) bacteria but has a narrower spectrum of activity against Gram negative bacteria than third generation Cephalosporins.
Cefuroxime works well on strains of bacteria that secrete beta lactamase such as H. influenzae, E.coli, Neisseria, Enterobacter, Klebsiella. However, unlike other 2nd generation Cephalosporins, the drug is not active against some anaerobic bacteria such as Bacteroides fragilis.
Cefuroxime works on some Gram (+) aerobic bacteria such as Staphylococcus aureus, S.aureus, Staphylococcus epidermidis
In addition, the drug is also effective on Haemophilus influenzae, H. parainfluenzae, Neisseria gonorrhoeae,...
With a spectrum Antibacterial drugs are indicated for use in infections caused by susceptible bacteria such as:
Severe infections of the lower respiratory tract (including pneumonia); Skin and soft tissue infections; Bone and joint infections; Severe urogenital - genitourinary infections; Blood infection ; Meningitis . In addition, the drug is also used to prevent infections in other cardiovascular and thoracic surgery, bone and joint surgery, digestive, obstetrics and gynecology.
3. How to use Glanax?
Dosage of Glanax:
For adults, 750mg of the drug is usually used every 8 hours, but in severe infections the dose can be up to 1.5g intravenously, the doses are spaced 8 or 6 hours apart. For children and very young children, each kg of body weight is used from 30mg to 60mg of the drug per day, if necessary, it can be increased to 100mg of the drug / day, divided into 3 to 4 small doses. When using the drug to treat meningitis caused by susceptible strains of bacteria in adults intravenously at a dose of 3g, every 8 hours; in children and very young children, 200 to 240 mg per day intravenously, divided into 3 to 4 small doses; After 72 hours or when clinical symptoms have improved, the dose can be reduced to 100 mg/kg per day. Gonorrhea intramuscular injection of a single dose of Glanax 1.5g. For the prevention of infection during surgery, a dose of 1.5 g intravenously before surgery, then continued intramuscularly at 750 mg every 8 hours for the next 24-48 hours. How to use and some notes when using Glanax:
For patients with kidney failure, the doctor may prescribe a dose reduction. Do not use Glanax 1.5g for people who are allergic to Cephalosporin antibiotics. Glanax 1.5 can be administered intramuscularly, direct intravenous injection, intermittent intravenous infusion and continuous intravenous infusion. For intramuscular injection, it is necessary to mix 6ml of sterile distilled water with the powder for injection in the vial, then shake the suspension for injection. When injecting, it is necessary to inject deep into large muscle areas such as the buttocks or inner thighs. For direct intravenous injection, it is necessary to mix 1.5 g of powder for injection in a vial with 16 ml of distilled water for injection. The resulting solution can be administered by slow injection directly into a vein or into an infusion line containing suitable infusion over at least 5 minutes. For intermittent intravenous infusion or continuous infusion, use 100 ml of distilled water for injection or 0.9% sodium chloride solution or 5% dextrose solution to add to the infusion bag containing Glanax 1.5 g or transfer the powder solution. reconstitute the dissolved drug into glass or PVC infusion bottles containing a suitable solvent. Intermittent intravenous infusion usually lasts between 15-60 minutes. Drugs such as strong diuretics, Aminoglycosides can cause interactions when used with Glanax. Tell your doctor if you have ever had an anaphylactic reaction while using penicillin, or have a gastrointestinal condition (especially colitis). Use caution when using Glanax for pregnant or lactating women. In case of drug overdose can be seen increased neuromuscular excitability, even convulsions, especially in people with renal failure. Ensure ventilation and perfusion of the patient, discontinue the drug immediately if a seizure occurs, and initiate anticonvulsant therapy if necessary. Glanax medicine can cause some of the following disorders, tell your doctor if you have:
Digestive disorders such as vomiting, nausea, diarrhea; Anaphylactic reactions; Eosinophilia; Urticaria; Itchy; Headache; Interstitial nephritis ; Pseudomembranous colitis; Stevens Johnson syndrome ; Thrombophlebitis; Pain at the injection site. Store the sterile powder before reconstitution at a temperature not higher than 30°C. The reconstituted solution should be used immediately or, if not used in time, can be stored in a refrigerator between 2°C and 8°C for no more than 12 hours.
In short, Glanax 1.5g is an injectable drug, to ensure safety when using and avoid the risk of unwanted complications, you need to use the drug under the supervision of medical staff.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
