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Gelabee is manufactured and registered by Phil Inter Pharma Co., Ltd., belongs to the group of minerals and vitamins. Let's learn the ingredients, uses and usage of Gelabee through the article below.
1. What is Galabee?
Galabee's main ingredients are:
Thiamin nitrate (vitamin B1) with a content of 100mg; Pyridoxine HCl (vitamin B6) 200mg; Cyanocobalamin (vitamin B12) 200mcg. The drug is prepared in the form of soft capsules, packed in boxes of 5 blisters and 10 blisters, 1 blister of 10 tablets.
2. Pharmacodynamics and pharmacokinetics of Galabee
Pharmacodynamics:
Galabee drug contains B1, B6, B12 all belong to group B vitamins, water soluble, acting as a coenzyme in the process of intermediary metabolism of the central nervous system and peripheral nervous system. Like other vitamins, they are essential nutrients that the body cannot synthesize on its own. Using each vitamin alone is not as effective as using a combination of B vitamins, helping to accelerate the repair processes of nerve fiber damage leading to enhanced muscle recovery and muscle strength. . Pharmacokinetics:
Thiamine nitrate: Na+-dependent active transport determines the absorption of Thiamine in the gastrointestinal tract, however, when thiamin concentrations reach high levels in the gastrointestinal tract Passive diffusion also plays an important role. When administered intramuscularly, thiamin is rapidly absorbed, distributed in milk and most tissues. Thiamin is completely broken down by about 1mg per day in tissues, which is also the minimum amount that the body needs daily. Thiamine will be eliminated in the urine. Pyridoxine HCl: Pyridoxine is rapidly absorbed from the gastrointestinal tract, most of the drug is stored mainly in the liver and partly distributed in the brain and muscles. Pyridoxine is eliminated as metabolites mainly by the kidneys, if the amount taken exceeds the body's needs, it will be eliminated unchanged. Cyanocobalamin: Vitamin B12 is absorbed into the body through the intestinal tract, mainly in the ileum by two mechanisms: Positive mechanism, absorption of physiological doses, needing the help of intrinsic factor is secreted glycoprotein produced by parietal cells of the gastric mucosa; Passive mechanism when using a large amount of the drug. The extent of absorption is independent of dose and is about 1%, so just 1mg a day can satisfy the body's needs and can treat all forms of vitamin B12 deficiency.
3. Uses of the drug Galabee
Indications of the drug Galabee:
Galabee is indicated for the treatment of cases with peripheral nerve disorders: neuralgia, polyneuritis, shoulder-arm syndrome, sciatica, pain back – lumbar, trigeminal neuralgia, intercostal neuralgia, numbness of extremities; Treatment of neurological diseases caused by causes such as diabetes, alcoholism, drugs; Galabee supports the treatment of joint pain; In addition, it is also indicated for the treatment of disorders caused by deficiency of one of the three vitamins B1, B6, B12 such as: peripheral neuritis, beriberi, convulsions in children due to vitamin B6 deficiency, and anemia. iron shavings. Contraindications of the drug Galabee:
Galabee drug is not indicated for cases of hypersensitivity to any component of the drug including the main active ingredients and excipients; Cases of suspected malignancy or existing malignancies are not indicated to use Galabee ; Do not give Galabee to children under 18 years of age.
4. Dosage and usage of the drug Galabee
The basic dosage for Galabee is: 1 tablet/day. For special cases, the dose can be increased to 1 tablet x 3 times in 1 day. Depending on each specific object, the subjects need to follow the prescribed dose of the prescribing doctor; On pregnant women should use a dose of 1 tablet per day; The maximum dose of Galabee is 4 weeks. Depending on each case and individual, the treating doctor will decide the appropriate time to use the drug, after the treatment period, depending on the degree of remission of the disease, each patient will be guided guide to appropriate dose reduction.
5. Drug interactions
Levodopa will be reduced when used with high doses of GBL (Gamma Butyrolactone).
6. Undesirable effects
Thiamine: Side effects are very rare (anaphylaxis, profuse sweating, dyspnea, acute hypertension, urticaria, pruritus), common in allergic pattern; Pyridoxi: Long-term use of 200 mg per day (> 2 months) can cause severe peripheral neuropathy, progressing from frostbite, unsteady gait to clumsiness and frostbite. hand. These conditions will be restored when the patient stops using the drug, but still leaves some sequelae; Cyanocobalamin: Usually vitamin B12 when used is very safe for the body, but when using vitamin B12 in high doses, such as when used to treat deficiency can have undesirable effects such as fatigue, headache. , dizziness, nausea, vomiting. Above is all information about Galabee drug. To ensure the safety of your health and maximize the effectiveness of treatment, you need to take the medicine exactly as directed by your doctor.
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