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Gadoxime 200 contains the main ingredient Cefpodoxime to help treat respiratory tract infections, skin infections, urinary tract infections and gonorrhea...
1. What is Gadoxime 200?
Gadoxime 200 belongs to the group of anti-parasitic, anti-infective, anti-fungal and viral drugs. The drug is available in the form of dispersible tablets. Each Gadoxime 200 tablet contains the following ingredients:
Cefpodoxime proxetil 200mg. Excipients just enough for 1 tablet include Kollidon CL, Lactose, Magnesium stearate, PVP, Talc Powder, Aerosil, Starch 1500, DST, Sodium lauryl sulfate, Lemon flavor powder and Sacralose.
2. Effects of Gadoxime 200
Gadoxime 200 is indicated in the treatment of the following cases:
Mild to moderate lower respiratory tract infections, including community-acquired acute pneumonia caused by S. pneumoniae or H. influenzae. Treatment of acute exacerbations of chronic bronchitis caused by S. pneumoniae, H. influenzae, M. catarrhalis that do not produce beta-lactamase. Gadoxime 200 is an alternative to the main treatment in mild and moderate upper respiratory tract infections such as sore throat, tonsillitis caused by S. pyogenes. Otitis media caused by H. influenzae, S. pneumoniae or B. catarrhalis. Uncomplicated mild to moderate urinary tract infections caused by K. pneumoniae, E. coli, P. mirabilis or S. saprophyticus. Gadoxime 200 treats uncomplicated mild and moderate skin infections caused by S. aureus, S. epidermidis with or without beta-lactamase production. Uncomplicated acute gonococcal infection in the endometrium or anus in women and the urethra in men and women caused by non-penicillinase-producing strains of N. gonorrhoeae.
3. Usage and dosage of Gadoxime 200
How to use Gadoxime 200:
Gadoxime 200 is used orally. Only use Gadoxime 200 when prescribed by a doctor. Take Gadoxime 200 with meals to increase absorption from the gastrointestinal tract. Adjust the dose of Gadoxime 200 for patients with renal impairment. Dosage of Gadoxime 200:
Adults and children over 13 years old:
Treatment of acute exacerbation of chronic bronchitis, community-acquired acute pneumonia: 1 tablet/time x 2 times/day, for treatment in 10 - 14 days. Pharyngitis and tonsillitis, uncomplicated urinary tract infections: Take 1⁄2 tablets/time x 2 times/day, treat for 5-10 days. Skin and tissue infections: Take 2 tablets/time x 2 times/day, treat for 7-14 days. Gonococcal infection: Take a single tablet, then continue treatment with Doxycycline to prevent Chlamydia infection. Dosage for children under 13 years old:
Children from 5 months to 12 years old: Treatment of acute otitis media: Use a dose of 5mg/kg (maximum 200mg) every 12 hours or 10mg/kg (maximum 400mg) every 24 hours. Treatment for 10 days. Bronchitis, mild and moderate tonsillitis: Dose of 5mg/kg (maximum 100mg) every 12 hours, used for 5-10 days. Treatment of other infections: Children from 15 days to 6 months old: Use dose 8mg/kg divided into 2 times/day. From 6 months to 2 years old: Use dose 40mg/time x 2 times/day. From 3-8 years old: Use dose 80mg/time x 2 times/day. From 9-13 years old: Use dose of 100mg/time x 2 times/day. Gadoxime 200 dose for patients with renal impairment:
When creatinine clearance < 30ml/min, not on hemodialysis: Use dose every 24 hours. On hemodialysis: Dose 3 times/week.
4. How to handle when you forget or overdose Gadoxime 200
In case you miss a dose of Gadoxime 200, take the missed dose as soon as you remember it. However, if it is almost time for your next dose of Gadoxime 200, skip the missed dose and take your next dose as scheduled.
Gadoxime 200 overdose will have symptoms such as vomiting, nausea, epigastric pain or diarrhea. Currently, there is no specific drug to treat Gadoxime 200 overdose, the main measures to deal with symptoms include:
Gastric lavage. Hemodialysis or peritoneal dialysis to reduce Gadoxime concentrations.
5. Contraindications to the use of Gadoxime 200
Do not use Gadoxime 200 in the following cases:
Allergic to components of Gadoxime 200. People with porphyrin metabolism disorders.
6. Undesirable effects when using Gadoxime 200
During the use of Gadoxime 200, patients may experience the following undesirable effects:
Nausea, vomiting, diarrhea or abdominal pain; Headache; Itching, skin rash, hives; Fever, joint pain; Anaphylaxis, erythema; Liver enzyme disorders, hepatitis or cholestatic jaundice; Blood disorders, eosinophilia; Interstitial nephritis ; Difficulty sleeping, confusion, hypertonia; Dizziness; Easily agitated. When experiencing any side effects of the drug, the patient should immediately inform the doctor for appropriate treatment.
7. Gadoxime 200 . drug interactions
Some drug interactions need attention if combined with Gadoxime:
Antacids, H2 antagonists reduce Gadoxime absorption when used concurrently. Concomitant use with uric acid in urine will increase the activity of Gadoxime. Probenecid reduces the renal excretion of Gadoxime. The typhoid vaccine is reduced in activity when used concurrently with Gadoxime.
8. Note when using Gadoxime 200 and how to store it
For pregnant and lactating women: There is no strict control on pregnant women, so only use Gadoxime when absolutely necessary and need to consult a doctor. Cefpodoxime is excreted in breast milk in small concentrations but can cause intestinal microflora disturbances and affect the child's body, so the use of the drug should be carefully considered. Gadoxime medicine causes headache, dizziness, so it is necessary to be careful when driving and operating machinery. Before using Gadoxime, patients need to inform their doctor about other drugs they are using, history of allergies. Monitor for signs of anaphylaxis at the first dose. If hypersensitivity reactions occur, discontinue the drug and switch to a more suitable alternative. Store the medicine in a cool place, away from moisture and direct light. Above are the uses, doses and notes when using Gadoxime 200. To ensure the safety of your health and maximize the effectiveness of treatment, you need to take the medicine exactly as directed by your doctor.
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