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Frantel drug has the active ingredient Albendazole 400mg and other excipients in sufficient quantity. This is an antibiotic that is used to treat parasites, bacteria, viruses, and fungi.
1. What is Frantel?
What is Frantel drug? Frantel drug has the active ingredient Albendazole 400mg and other excipients in sufficient quantity. This is an antibiotic that is used to treat parasites, bacteria, viruses, and fungi.
Frantel drug is made in the form of tablets, suitable for direct oral use. The drug is packaged in a box of 1 blister, each blister contains 1 tablet.
1.1. Pharmacodynamics of active ingredient Albendazole Active ingredient Albendazole has the effect of killing eggs, larvae and adult worms. Albendazole active ingredient has the effect of inhibiting glucose absorption, thus causing the worm to lose energy not enough to live, causing immobility and then death, the worm's carcass is pushed out by intestinal peristalsis. 1.2. Pharmacokinetics of active ingredient Albendazole Absorption: Active ingredient Albendazole is absorbed orally, bioavailability is as low as 20%. The use of fats may increase drug absorption. Elimination ability: the drug is excreted mainly in the feces 90-95%, only a small amount is excreted in the urine. 1.3. Albendazole active ingredient Albendazole is a benzimidazol carbamate derivative, with a broad spectrum of activity on intestinal worms such as roundworms, pinworms, strongyloides, hookworms, roundworms, beakworms, whipworms, and whipworms. muscle and skin larvae, tapeworms and tissue tapeworm larvae. The mechanism of action of the active ingredient Albendazol is to bind to the tubules of the parasite, thereby inhibiting the polymerization of the tubules into microtubules, preventing the activity of the parasite's cytoplasm. From there, this drug causes the parasite to be destroyed. Active ingredient Albendazole is active against the adult and larval stages of intestinal worms, killing eggs of roundworms and whipworms. The main metabolite of Albendazole is Albendazole Sulfoxid, which is still active and holds an important position in the pharmacological action of the drug.
2. What are the effects of Frantel?
What does Frantel do? Frantel is used to treat infections with one or more intestinal parasites such as roundworms, pinworms, whipworms, strongyloides, hookworms, melon seed flukes, beef tapeworms, swine flukes, liver flukes, Opisthorchis viverrini species. and type O. sinensis.
3. Usage and dosage of the drug Frantel
Usage and dosage of the drug Frantel is as follows:
3.1. Dosage of the drug Frantel Drug Frantel 400mg is made in the form of tablets, suitable for oral use, with the dosage instructions as follows:
Dosage to treat roundworms, whipworms, pinworms, worms For adults and children over 2 years old: a single dose of 400mg. Dosage for treatment of strongyloidiasis, fluke, Taenia, Hymenolepis for adults and children over 2 years old: use 1 therapeutic dose of 400mg/day for 3 days. Dosage for treatment of small liver flukes: 400mg x 2 times/day for 3 days. Dosage for treatment of Giardia disease Only in children aged 2-12 years: 400mg/time/day for 5 days. It should be noted: You need to absolutely comply with the regulations on the therapeutic dose recommended by the doctors, only adjust the therapeutic dose under the guidance of the treating doctor or professional pharmacist.
3.2. How to use Frantel 400mg Drug Frantel 400mg has the best effect when the user maintains regular use of the drug and the prescribed dose.
In addition, during the use of the drug, you should combine with a reasonable rest and a healthy diet menu, increase your intake of vegetables and fruits to supplement vitamins and minerals that have beneficial to the body. Besides, you should also combine exercise and sports to improve health and immune system.
4. Undesirable effects of the drug Frantel
During the use of Frantel, you may experience some specific unwanted effects as follows: rarely, symptoms such as nausea, vomiting, epigastric pain, hair loss with prolonged use , headache, dizziness, allergic reaction (rash, itching, urticaria, ...)
You need to proactively notify your doctor immediately if you encounter the above signs or abnormalities in the process of using Frantel 400mg drug to be detected and handled promptly, minimizing possible serious consequences.
5. Drug interactions Frantel
Interactions of Frantel drugs that may occur during use are as follows:
Active ingredient Albendazole may interact with Praziquatel, increasing plasma concentrations of the metabolized form of Albendazole. Cimetindein can interact with the active ingredient Albendazole to increase the concentration of Albendazole in bile and follicular fluid by 2-fold, the plasma concentration unchanged. Dexamethasone: may increase the volume under the AUC curve of active ingredient Albendazole. If you are using any medicine, you should proactively inform your treating doctor, pharmacist, and adjust accordingly.
6. Some notes when using Frantel
6.1. Contraindications of the drug Frantel: Patients with hypersensitivity or history of hypersensitivity to Albendazole active ingredients or other components of the drug. Women who are pregnant or who are suspected of becoming pregnant People with liver failure such as cirrhosis People with a history of previous bone marrow toxicity. 6.2. Notes and cautions when using Frantel medicine Read carefully the instructions for use listed on the label before using Frantel 400mg and consult your treating doctor or pharmacist if you have any questions about the product. Use caution when using Frantel for patients with a history of myocardial infarction, people with cerebral vascular occlusion, the elderly (over 65 years old). For drivers and operators: Frantel 400mg can be used to drive and operate machines. The reason is that this drug does not cause drowsiness, fatigue during use. 6.3. Note on pregnant women and lactating women For pregnant women: Frantel should not be used in pregnant women unless it is imperative to use it without any other way. The patient must not become pregnant for at least 1 month after taking the drug containing the active ingredient Albendazole. If a patient who is using this drug becomes pregnant, she must stop taking the drug immediately and understand that the drug can cause very serious harm to the fetus.
For breastfeeding women should not use Albendazole active ingredient.
6.4. How to store Frantel medicines Store Frantel medicinal products in areas where the temperature does not exceed 30 degrees C. Limit Frantel medicinal products in humid areas or places with air humidity exceeding 70%. such as refrigerators,... Store Frantel medicines out of the reach of children or pets in your family. Above is all information about Frantel drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Frantel medicine to treat the disease at home, because there may be unwanted side effects on health.
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