Uses of Idomagi

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1. What is Idomagi?

What is Idomagi drug? The drug Idomagi belongs to the group of drugs that treat parasites, anti-infectives, antivirals, and antifungals. Idomagi is prepared in the form of film-coated tablets in a box of 3 blisters x 10 tablets and a box of 10 blisters x 10 tablets.
Idomagi medicine has the main ingredient of 600mg Linezolid and other excipients in the drug.

2. Indications for use of Idomagi

Idomagi is used in the treatment of infections caused by specific susceptible strains of bacteria in the following cases:
Infections caused by vancomycin-resistant Enterococcus faecum, including sepsis. Nosocomial pneumonia caused by Staphylococcus aureus (effective against both methicillin-resistant and susceptible strains). Complicated skin infections caused by Staphylococcus aureus (active against both methicillin-resistant and susceptible strains), Streptococcus agalactiae, Streptococcus pyogenes. Uncomplicated skin infections caused by Staphylococcus aureus (active against both methicillin-resistant and susceptible strains), Streptococcus pyogenes. Community-acquired pneumonia caused by Streptococcus pneumoniae (only effective against penicillin and susceptible strains), Staphylococcus aureus (only effective against methicillin-susceptible strains) and including cases of ongoing bacteremia.

3. Dosage - How to take Idomagi

Idomagi is used for oral administration, the patient can take the drug on an empty or full stomach. Patients should strictly follow the instructions of the doctor or pharmacist.
Usual dose of Idomagi:
Infections caused by vancomycin-resistant Enterococcus faecum: 600mg Linezolid x 2 times/day x 14 - 28 days. Nosocomial pneumonia, complicated skin infections, community-acquired pneumonia: 600mg Linezolid x 2 times/day x 10-14 days. Uncomplicated skin infections: 400mg Linezolid x 2 times/day x 10-14 days. No dose adjustment of Linezolid is required for patients with renal and hepatic impairment. In the case of Idomagi treatment for elderly patients, no dose adjustment is required. The specific duration of Linezolid treatment depends on the location and extent of the infection as well as the patient's clinical response. The maximum duration of Idomagi treatment is 28 days. The safety and effectiveness of Idomagi when taken for longer than 28 days have not been established. It is not recommended to increase the dose of Linezolid or prolong therapy in patients with concomitant sepsis-associated infections.

4. Contraindications to Idomagi

Idomagi drug is not used in the following cases:
Patients with hypersensitivity, history of allergy to Linezolid or to any ingredient of the drug. Patients who are taking or have used monoamine oxidase A or B inhibitors such as Isocarboxazid, Phenelzin, Selegiline, Moclobemide within the past 2 weeks. Patients with uncontrolled hypertension, bipolar depression, pheochromocytoma, thyrotoxicosis, schizophrenia, carcinoid, acute cognitive dysfunction. The patient is taking any Serotonin reuptake inhibitors, serotonin 5HT1 receptor antagonists (triptans), tricyclic antidepressants, direct or indirect sympathomimetic agents (bronchodilators acting as bronchodilators). Sympathomimetics, Phenylpropanolamine, Pseudoephedrine), vasoconstrictors (Epinephrine, Norepinephrine), drugs with dopamine-like effects (Dopamine, Dobutamine), Buspiron or Pethidine. Idomagi should not be administered to a nursing woman, as there are animal data showing that Linezolid and its metabolites may pass into breast milk. Therefore, breastfeeding should be discontinued before and during the use of Idomagi.

5. Idomagi drug interactions

When Idomagi is combined with some of the following drugs, there may be drug interactions such as:
Drugs such as Epinephrine, Adrenergic, Dopamine, Phenylpropanolamine and Pseudoephedrine combined with Idomagi can cause high blood pressure. Concurrent use of Idomagi with Tramadol may increase the risk of seizures. When combined with Idomagi with MAOIs potentially fatal. Therefore, avoid concomitant use of Idomagi or use within 2 weeks of discontinuation of an MAOI to reduce the risk of hypertension. Beverages and foods high in tyramine such as cheese, yeast extracts, alcoholic beverages and fermented soy products such as soy sauce used in combination with Linezolid may cause an increase in blood pressure. In each meal avoid taking Tyramine ≥ 100mg. Avoid taking Linezolid with drugs that may pose a risk of monoamine oxidase (MAO) inhibition, as Linezolid is a reversible, non-selective monoamine oxidase (MAO) inhibitor. If combined, it is necessary to closely monitor and supervise drug users. The potential for Idomagi drug interactions with dextromethorphan has been studied in healthy volunteers. Clinically, when Linezolid is used together with Serotonin-related drugs, antidepressants, selective Serotonin reuptake inhibitors (SSRIs). Therefore, it is advisable to monitor patients treated with Linezolid. and Serotonergic drugs are needed.

6. Side effects when taking Idomagi

During the use of Idomagi medicine, patients may experience some unwanted side effects as follows:
Common
Infections and parasites: Oral candidiasis and vaginal candidiasis . Nervous system disorders: Headache, taste deviation. Gastrointestinal disorders: Diarrhea, nausea/vomiting. Hepatobiliary disorders: Abnormal liver function, increased ALT, AST or alkaline phosphate. Renal and urinary disorders: Increased Blood urea nitrogen. Chemistry: Increases LDH, Creatin kinase, Amylase, Lipase or blood glucose. Decrease total protein, sodium, albumin, or calcium. Increased potassium, decreased potassium or increased bicarbonate. Hematology: Increased neutrophils or eosinophils. Decrease in hematocrit, hemoglobin, or red blood cell count. Thrombocytopenia, leukocytosis, thrombocytopenia or leukopenia. Uncommon
Infections and parasitic infections: Vaginitis. Blood and lymphatic system disorders: Leukopenia, thrombocytopenia, neutropenia, eosinophilia. Psychiatric disorders: Insomnia. Nervous system disorders: Paresthesia, dizziness, somnolence. Eye disorders: Blurred vision. Ear and Labyrinth Disorders: Tinnitus. Vascular disorders: High blood pressure, phlebitis, thrombophlebitis. Digestive disorders: Pancreatitis, glossitis, stomatitis, gastritis, loose stools, localized or diffuse abdominal pain, constipation, dry mouth, dyspepsia, tongue discoloration or disorder. Hepatobiliary disorders: Increased bilirubin. Skin and subcutaneous soft tissue disorders: Dermatitis, urticaria, pruritus, diaphoresis, rash. Renal and urinary disorders: Increased creatinine, polyuria. Reproductive system disorders: Vaginal disorders. General disorders: Fever, Chills, fatigue, thirst. Chemical: Decrease in blood sugar, increase in sodium or calcium, increase or decrease in chloride. Hematology: Decreased neutrophils, increased reticulocyte count. Rare
Heart disorder: Tachycardia. Vascular disorders: Cerebral ischemic attack Renal and urinary disorders: Renal failure. Idomagi should be discontinued in the event of mild adverse reactions, severe hypersensitivity or allergic reactions, requiring supportive treatment (retention and use of epinephrine, antihistamines, oxygen, corticosteroids). ...) and inform the doctor, pharmacist about the unwanted effects encountered when using the drug Idomagi.

7. Precautions when using Idomagi

Idomagi should be used with caution in people with a history of myelosuppression, renal failure, uncontrolled hypertension, adrenal myeloma, chronic infections, carcinoid syndrome, bipolar depression, hyperthyroidism untreated, history of seizures, schizophrenia, or acute comatose states. Patients should be monitored weekly complete blood count, taking medication after hemodialysis. Keep Idomagi out of reach of children. Patients should use Idomagi with caution while driving or operating machinery, because unwanted effects such as dizziness or visual impairment may occur when using Linezolid. Basically, the drug Idomagi works in treating and preventing bacterial infections. Before taking Idomagi, patients should carefully read the instructions for use and strictly follow the instructions for taking the medicine from the doctor or pharmacist. best results.
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