This is an automatically translated article.
Flamilium is made in the form of tablets, with the main ingredient domperidone. The drug is used to treat certain diseases of the gastrointestinal tract. The following article will provide readers with a lot of useful information about this drug.
1. What are the effects of Flamilium?
1 Flamilium tablet has the main ingredient Domperidone 10mg and other excipients. Domperidone is an antiemetic drug, with dopamine antagonist activity, properties similar to metoclopramide hydrochloride. Because the drug Flamilium has almost no effect on dopamine receptors in the brain, Domperidone does not affect the mind and nerves.
Domperidone stimulates peristalsis of the gastrointestinal tract, increases cardiac sphincter tone and increases the amplitude of pyloric sphincter expansion after meals, but does not affect gastric secretion. It is used to treat symptoms of acute nausea and vomiting, both nausea and vomiting, caused by the administration of Bromocriptin and Levodopa in patients with Parkinson's disease. Flamilium is used to treat symptoms of upper gastrointestinal motility disorders associated with chronic, subacute gastritis and diabetic gastroparesis. Flamilium can also be used to prevent gastrointestinal symptoms associated with anti-Parkinsonian dopamine agonists.
Use Flamilium in the following cases:
Treatment of severe nausea and vomiting symptoms, especially in patients being treated with cytotoxic drugs; Treatment of symptoms of nausea, vomiting, feeling of bloating and heaviness in the epigastrium, dyspepsia after meals due to slow digestion of food into the intestines. Do not use Flamilium in the following cases:
People with hypersensitivity to Domperidone or any component of the preparation; People with prolactin-secreting pituitary gland tumors; In combination with oral ketoconazole; Domperidone should not be used in the following cases: Irritation of the gastrointestinal tract that may cause danger, perforation of the gastrointestinal tract or mechanical obstruction; Do not use Flamilium if it has passed the expiration date on the package.
2. How to use and dose Flamilium
Use oral Flamilium. Take Flamilium 15 - 30 minutes before meals and in case of need, before going to bed.
For adults: Each time take 10mg x 4 times/day. If necessary, this dose can be doubled after 2 weeks, when the full therapeutic response is not achieved, the maximum dose is 80mg per day; Children 2 years and older: The recommended dose of Flamilium for children is 0.2 - 0.5 mg/kg/time x 3 - 4 times/day; The maximum dose is 2.4 mg/kg (take care not to exceed a total dose of 80 mg per day). However, it should also be remembered that Domperidone tablets are not suitable for use in children weighing less than 35kg; Renal Impairment: It is uncertain whether the dose should be adjusted for patients with renal impairment when used once. However, if used continuously, it should be noted to reduce the number of times to 1 or 2 times per day depending on the severity of the disease. Dosage should also be reduced. In general, patients with renal impairment should be regularly and regularly evaluated if Flamilium is used for long periods of time. Missed dose once: Do not take a double dose if you accidentally forget to use the medicine. If you miss a dose of Flamilium, you should take it again as soon as you remember and then use the next dose as scheduled.
Overdose:
Signs of overdose when using Flamilium are somnolence, disorientation, extrapyramidal reactions, especially in children; In the treatment of overdosage with Flamilium, it is necessary to treat with activated charcoal and closely monitor the patient. Parkinson's drugs, anticholinergics or antihistamines with anticholinergic properties may be beneficial in controlling extrapyramidal reactions.
3. Undesirable effects when using Flamilium
When taking Flamilium, patients may experience some side effects such as:
On the central nervous system: Dry mouth, headache or migraine, insomnia, dizziness, agitation, thirst, lethargy , stimulate; Digestive: Abdominal cramps, heartburn, diarrhea, nausea, appetite changes, heartburn, constipation; Endocrine: Breast pain, hot flashes, increased lactation, regular menstruation, breast enlargement in men; Mucosal - skin: Itching, urticaria, rash, conjunctivitis, stomatitis; Urinary: Difficulty urinating, dry urination; Cardiovascular: Palpitations, edema; Musculoskeletal: Fatigue, limb contracture; Other side effects: Drug intolerance; Laboratory parameters: Increase in serum prolactin, increase in ALT, AST and cholesterol. Patients should note to inform their doctors about the side effects encountered when using Flamilium to have appropriate interventions.
4. Be careful when using Flamilium
Some things patients need to pay attention to when using Flamilium:
When the patient has lactation, breast enlargement in men, stopping Domperidone will relieve those symptoms; Do not use Flamilium for pregnant and lactating women; Due to common side effects such as: Drowsiness, dry mouth, disorientation, Flamilium should not be used while operating machinery or driving because of the high potential risk.
5. Flamilium drug interactions
Drug interactions can affect the effectiveness of one or more drugs or increase the risk of some side effects for the patient's health. Therefore, patients should not self-medicate, stop taking or change the use and dose of any medicine without the consent of the doctor.
Some problems with Flamilium drug interactions with other drugs that users need to be aware of:
Combining Flamilium with anticholinergic drugs may compromise the beneficial effects of Domperidone. Because domperidone increases gastric and small intestinal transit, it may increase the absorption of the drug from the small intestine but slow the absorption of the drug from the stomach; Caution should be exercised when domperidone is used in combination with MAO inhibitors; Co-administration of Flamilium with antacids or H2-receptor blockers does not reduce the absorption of domperidone. During the use of Flamilium, patients need to pay attention to remember and follow the doctor's instructions to achieve high effectiveness in treatment. In addition, patients also need to carefully read the instructions and note when using Flamilium.
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