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Fixnat 200 drug with the main ingredient is Cefpodoxime 200mg, which is commonly used in the treatment of mild to moderate infections in the respiratory tract, urinary tract, skin, gonorrhea... Find Understanding basic information such as ingredients, uses, doses and side effects of Fixnat 200 medicine will bring patients the best treatment results.
1. What is Fixnat 200?
Fixnat 200mg drug is prepared under film coated tablets, with main ingredients including:
Active ingredient: Cefpodoxime (in the form of Cefpodoxime proxetil) 200mg content. Excipients: Lactose monohydrate, Avicel M101, croscarmellose sodium, sodium lauryl sulfate, Magnesium stearate, Kollidon K80, Aerosil, HPMC 615, HPMC 608, PEG 6000, Titanium dioxide just enough for 1 200 mg tablet. Pharmacodynamics:
Cefpodoxime is an antibiotic belonging to the 3rd generation Cephalosporin group, with a broad antibacterial spectrum. The main bactericidal mechanism of this active ingredient is acylation of membrane-bound transpeptidase enzymes, thereby inhibiting the cross-linking of peptidoglycan chains necessary for the strength and durability of the bacterial cell wall. prevent bacteria from synthesizing the cell wall.
Most of the antibiotics belonging to the 3rd generation Cephalosporin group are resistant to Beta Lactamases secreted by Gram-positive and Gram-negative bacteria, so Cefpodoxime has a fairly broad antibacterial spectrum such as:
Gram-positive cocci such as Streptococcus pneumoniae. Streptococcus Streptococcus. Staphylococci such as Staphylococcus aureus or Staphylococcus epidermidis. Gram-positive bacilli. Gram-negative bacteria such as: E.coli, Proteus mirabilis, Klebsiella.
2. What are the effects of Fixnat 200?
Fixnat 200 mg is indicated for the treatment of mild to moderate bacterial infections in the following cases:
Upper and lower respiratory tract infections such as sore throat, otitis media, tonsillitis, bronchitis, inflammation lung . Urinary tract infections such as pyelonephritis, urethritis, cystitis. Skin infections. Uncomplicated gonorrhea in both women and men.
3. Contraindications of Fixnat 200:
Hypersensitivity to any component of Fixnat 200. History of allergy to antibiotics containing Cefpodoxime. History of allergy to Cephalosporin antibiotics.
4. Dosage and how to use Fixnat 200
Dosage in adults or children > 13 years old:
Pharyngitis, tonsillitis: Dose: Take 1⁄2 tablets (100mg)/time x 2 times/day, for 5-10 days. Acute exacerbation in chronic bronchitis Dose: Take 1 tablet (200mg)/time x 2 times/day, for 10 days. Community-acquired pneumonia: Dose: Take 1 tablet (200mg)/time x 2 times/day, for 14 days. Urinary tract infections: Dose: Take 1⁄2 tablets (100mg)/time x 2 times/day, for 7 days. Skin infections: Dose: Take 2 tablets (400mg)/time x 2 times/day, for 7-14 days. Uncomplicated gonorrhea: Dose: Take 1 tablet (200mg) as a single dose, combined with Doxycycline. Dosage for children:
Acute otitis media: Dose for children 5 months - 12 years old: Take 5mg/kg/time x 2 times/day, maximum dose 200mg/time. Or take 10mg/kg/time x 1 time/day, maximum dose 400mg/time. Take the drug for 10 days. Tonsillitis, bronchitis: Dose for children 5 months - 12 years old: Take 5mg/kg/time x 2 times/day, the maximum dose is 100mg/time. Take the drug for 5 - 10 days. Other infections: Dose for children 9-13 years old: Take 1⁄2 tablets (100mg)/time x 2 times/day. Dose for children 3 - 8 years old: Take 80mg/time x 2 times/day. Dose for children 6 months to under 3 years old: 40mg/time x 2 times/day. Dose for children 15 days to under 6 months: Take 4mg/time x 2 times/day. Dose for children < 15 days: Not recommended. Patients with impaired renal function:
Adjust dose based on Creatinine clearance (CrCl) CrCl dose < 30ml/min and without dialysis: Take 1 tablet (200mg)/time x 1 time/day. Dose for dialysis patients: Take 1 tablet/time x 3 times/week.
5. Note when using Fixnat 200
Treatment with Fixnat 200mg drug with high dose or prolonged, can cause side effects such as:
Common: Gastrointestinal disturbances such as nausea, vomiting, abdominal pain, diarrhea. Skin symptoms such as rash, urticaria, itching. Neurological symptoms such as headache. Uncommon: Systemic symptoms such as erythema multiforme, fever, anaphylactic reactions. Serum sickness, joint pain. Hepatobiliary dysfunction such as elevated liver enzymes, hepatitis, cholestatic jaundice. Rare: Central nervous system symptoms such as agitation, trouble sleeping, dizziness, dizziness, confusion, hyperactivity, hypertonia. Eosinophilia, hemostatic dysfunction, interstitial nephritis. Should stop the drug when detecting the above symptoms after taking Fixnat 200 and promptly notify the treating doctor and immediately go to the nearest medical facility for supportive treatment.
Note to use Fixnat 200 in the following subjects:
Pregnant women: According to the US Food and Drug Administration (FDA), the antibiotics of the Cephalosporin group are classified as safe group B, group not yet There is evidence of a risk in pregnant women. Therefore, only use Fixnat 200 on this subject when the benefits outweigh the harms. Lactation: There are currently some studies showing that the active ingredient Cefpodoxime in Fixnat 200 can be excreted in breast milk, but at low concentrations. However, this will also affect the intestinal microbiota of the breastfed infant, and distort the results of antibiotic resistance in the case of bacterial infection in the newborn. Drivers or machine operators are not affected much after using Fixnat 200.
6. Fixnat 200 drug interactions
Interactions with other drugs:
Drugs that reduce the absorption of Fixnat 200: Antihistamines H2. Antacids. Drugs that increase blood levels of Fixnat 200: Probenecid. Monitor renal function when deciding to use Fixnat 200 with drugs containing nephrotoxic compounds. Above is general information and notes when using Fixnat 200. In order to bring the best treatment results for themselves and their families, patients should carefully read the instructions for use on the package of Fixnat 200 and strictly follow the instructions of the doctor / pharmacist.
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