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Fefurate is a drug used to treat or prevent anemia caused by iron deficiency and folic acid deficiency, especially in pregnant and lactating women and in malnourished patients. So how does Fefurate work and what should be noted when using the drug?1. What is Fefurate?
Fefurate has the main ingredients are Iron 2+ and folic acid. Uses of the ingredients are as follows:
Iron Ion: Iron 2+ ion is a trace element that is small but necessary for the body. This is necessary for the synthesis of hemoglobin of red blood cells, myoglobin and the respiratory enzyme cytochrome C. Iron ions are rapidly absorbed in the duodenum and proximal jejunum. After entering the body, iron is stored in the form of: Ferritin and hemosiderin, the rest is excreted in the feces. Folic Acid Ingredients: Folic acid is a B vitamin (vitamin B9). Folic acid occurs in nature as a polyglutamate. After entering the body, folic acid is reduced to tetrahydrofolate which is a coenzyme of many metabolic processes, synthesizing the nucleus of nucleotides. It is also involved in the metabolism of amino acids. The drug is distributed into tissues in the body rapidly after oral administration, enters the cerebrospinal fluid, placenta and breast milk. The drug is stored mainly in the liver and excreted in the urine.
2. Indications of the drug Fefurate
Fefurate is indicated in the following cases:
Iron deficiency anemia. Folic acid deficiency causes megaloblastic disease. Pregnant women with anemia need iron supplements, breastfeeding mothers lack nutrition. Lack of nutrients in the diet. Body weakness Patients recovering from major surgery: Gastrectomy, femur fracture,.. Folic acid deficiency in patients being treated with Methotrexate, antiepileptic drugs.
3. Contraindications of Fefurate
Cases where the patient should not take Fefurate:
Allergy to iron, folic acid or any ingredient of Fefurate; Liver disease, iron-contaminated tissue, hemosiderin infection; The patient is being treated for hemolytic anemia; Polycythemia vera; Gastrointestinal pouch pathology, esophageal stricture; Note when using Fefurate drug: Do not use the drug for a long time in patients with normal blood iron levels. Discontinue use in case of intolerance reactions.
4. Interactions of Fefurate with other drugs
Interactions of Fefurate with other drugs are as follows:
Anticonvulsants will be reduced due to folic acid in Fefurate. Oral contraceptives and Sulfasalazine when taken with Fefurate reduce the effectiveness of the drug. Antacids reduce the absorption of iron.
5. Usage and dosage of Fefurate
How to use: The drug is made in the form of tablets, so patients need to take the whole pill with water. Should be taken after meals to avoid effects on the gastrointestinal tract.
Dosage:
Prophylactic dose: 1 tablet/day. Dosage for treatment of iron deficiency anemia: 1 tablet x 2 times/day.
6. Side effects of the drug Fefurate
Some unwanted effects when using Fefurate are recorded as follows:
Itching, rash, allergic reactions. Get angry. Digestive disorders: dull epigastric pain, nausea, constipation or diarrhea. Black stools. In summary, Fefurate is a drug for the treatment and prevention of iron-deficiency anemia and nutritional deficiencies. The drug is relatively benign, easy to use and gives high treatment efficiency. However, patients should not abuse and arbitrarily use drugs without the direction of the doctor.
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