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Fascapin 20 is a drug for the treatment of essential hypertension, prevention of angina attacks due to the effect of dilating blood vessels, reducing peripheral resistance. So how does Fascapin 20 work for the body?1. What is Fascapin 20?
Fascapin 20 has the main ingredient Nifedipine - a calcium channel antagonist of the Dihydropyridine group in the treatment of hypertension. Fascapin 20 acts through the mechanism of selective inhibition of calcium ions into cardiac muscle cells and vascular smooth muscle, thereby dilating vasculature, reducing peripheral vascular resistance, causing hypotension. The nifedipine contained in Fascapin 20 also increases peripheral blood flow, increases blood flow to the kidneys and brain, and dilates arteries and arterioles. The drug does not increase heart rate. Fascapin 20 is rapidly absorbed from the gastrointestinal tract after only a few minutes of taking the drug. Almost the drug is bound to plasma proteins (90-95%), metabolised in the liver and excreted in the urine and feces.2. Indications of Fascapin 20
Fascapin 20 is indicated in the following pathological cases:
Idiopathic hypertension. Secondary hypertension. Prophylactic treatment of chronic stable or unstable angina, reducing the frequency of attacks, and Prinzmetal-type angina. Indications for the treatment of Raynaud's syndrome.
3. Contraindications of Fascapin 20
Cases in which Fascapin 20 should not be used:
Allergy to nifedipine or any of its ingredients. Acute myocardial infarction . Cardiac shock, unstable heart rate, aortic stenosis, decompensated heart failure. Low blood pressure. Women who are pregnant in the first 3 months. Children under 12 years of age should not use Fascapin 20 . Patients with porphyria. Notes when using Fascapin 20
Patients with systolic blood pressure < 90 mmHg need to follow the doctor's instructions to use the drug. Patients with hypovolemia, portal hypertension in cirrhosis should limit the use of Fascapin 20. The drug should be discontinued immediately when symptoms of epigastric burning and bloating are observed in patients with a history of gastric ulcer. - duodenum. Patients with heart failure, left ventricular function is impaired when using the drug. Patients with liver failure, diabetes need to reduce the dose of the drug. Grapefruit juice will change the drug metabolism. Fascapin 20 reduces vasoconstriction, possibly inhibiting labor during delivery.
4. Fascapin 20 interactions with other drugs
Co-administration of Fascapin 20 with beta-blockers increases drug effect and tolerance. However, there is a risk of excessive lowering of blood pressure, increasing the occurrence of angina.
ACE inhibitors, diuretics, nitrates, psychotropic drugs, Digoxin, Quinidine, Cimetidine, Coumarin, Cyclosporin can reduce the effect of Fascapin 20 when used together.
Antihistamine H2 used concurrently with Fascapin 20 increases the concentration of the drug in the blood, increasing the effect of the drug. When using, the dose should be adjusted accordingly.
Fentanyl combined with Fascapin 20 antihypertensive effect. During surgery, if high doses of fentanyl are used, nifedipine should be stopped or changed at least 36 hours before surgery.
Fascapin 20 reduces plasma concentrations of Theophylline. Non-steroidal anti-inflammatory drugs increase antagonism to the antihypertensive effect of Fascapin 20.
5. Dosage and how to use Fascapin 20
How to use
Take medicine with filtered water, do not chew, drink after meals to avoid stomach irritation.
Dosage
Myocardial ischemia or angina: 1 tablet (20mg) x 2 times/day. Maximum dose: 40mg (2 tablets) x 2 times/day. Primary or secondary hypertension: 1 tablet (20mg) x 2 times/day. Maximum dose: 40mg (2 tablets) x 2 times/day. The interval between 2 doses is 12 hours, at least 4 hours apart.
6. Fascapin 20 . side effects
Some unwanted effects may be encountered when using Fascapin 20:
Common
Headache, dizziness, dizziness. Tired, red face. Heart beats fast. Ankle edema Epigastric discomfort, nausea, vomiting, constipation or diarrhea,... Once you know the information about the uses and dosage, you can use Fascapin 20 according to the instructions above or you can use it as directed. Consult your prescribing physician for more information.
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