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Esolona belongs to the group of gastrointestinal drugs, with the main ingredient being Esomeprazole - a proton pump inhibitor (PPI). The drug is indicated for the treatment of gastric and duodenal ulcers caused by excessive secretion of gastric acid.1. What is Esolona?
Esolona is a drug indicated for the treatment of peptic ulcers.
Currently on the market there are 2 drugs Esolona , with different content and dosage as follows:
Esolona 20:
Esomeprazol : 20mg; Other excipients are sufficient. Esolona 40:
Esomeprazol: 40mg; Other excipients are sufficient. The drug is made in the form of capsules containing microparticles coated in the intestine, which enhances absorption and improves the therapeutic effect of the drug. Use orally.
2. What are the uses of Esolona?
The Esomeprazole component in Esolona, after entering the stomach, will bind to the enzyme H + / K + - ATPase (also known as the proton pump) in the parietal cells of the stomach, specifically inhibiting the action of this pump. This is the final stage of gastric acid secretion, which helps prevent acid secretion into the stomach lumen. As a result, it helps to inhibit gastric acid secretion when stimulated by any agent. This inhibitory effect on gastric acid secretion is dose related, so there are Esolona drugs with different concentrations of Esomeprazole on the market.3. Indications of the drug Esolona
Peptic ulcer:
Helicobacter Pylori (HP): This is the main cause of peptic ulcer. In this case, in addition to using Esolona to treat ulcer symptoms, it is imperative to combine with antibiotics to eradicate HP bacteria. Drug-induced: The long-term use of high-dose non-steroidal anti-inflammatory drugs (NSAIDs) will degrade and decrease the synthesis of gastric mucosal barrier factors, reducing gastric mucosal blood flow. .... Or use antibiotics, reduce mucus secretion, anti-platelet aggregation ... long term will lead to peptic ulcer. At this time, in addition to considering stopping or changing the above drugs, it is necessary to combine drugs of the PPI group for treatment, in which Esolona with the main ingredient is Esomeprazole is recommended. Due to eating and living habits: Habit of using stimulants such as caffeine, alcohol, beer, other alcoholic beverages, tobacco, unhealthy food, skipping meals, staying up late... Prolonged and frequent repetition will lead to peptic ulcer disease due to a decrease in the protective barrier of the gastric mucosa and increased secretion of gastric acid. At that time, in addition to regulating eating and living habits, it is also necessary to combine with Esolona medicine. Due to psychological stress: The nervous tension, anxiety, psychological trauma ... often, for a long time, will affect the secretion of stomach acid, namely increase the secretion of gastric acid, leading to peptic ulcer disease. Not only that, the above factors also affect the treatment results of peptic ulcers. Therefore, it is necessary to first treat the cause, balance and relieve the psychological factors, in parallel with the use of drugs that inhibit gastric acid secretion, Esolona . Gastroesophageal reflux disease (GERD):
Frequent acid reflux into the esophagus leads to irritation of the lining of the esophagus, over time this condition is left untreated leading to worsening symptoms. heavier. In addition to treating the cause, it is also necessary to combine symptomatic treatment. The use of drugs that reduce the production of gastric acid, in which Esolona is also indicated. Prophylaxis and recurrence of peptic ulcers:
Prolonged use of anti-inflammatory analgesics will lead to increased gastric acid secretion, so it is necessary to use drugs that reduce secretion or inhibit acid secretion. stomach to prevent possible symptoms. Zollinger-Ellison syndrome:
An increase in gastrin levels in the blood due to tumors will stimulate the stomach lining to secrete too much gastric acid. In addition to treating the cause, it is necessary to combine with drugs that inhibit gastric acid secretion. In which, Esolona can be used.
4. Contraindications of Esolona
Do not use the drug on children; Contraindicated for people with hypersensitivity to any component of the drug.
5. Undesirable effects
Digestive disorders may appear such as: Nausea, vomiting, abdominal pain, bloating, diarrhea, constipation, dry mouth... Nervous system disorders: Dizziness, headache... Allergic reactions: Angioedema, anaphylaxis, skin rash, Stevens-Johnson syndrome...
6. Dosage, how to use Esolona
Treatment of duodenal ulcer: 20mg/day x 2-4 weeks; Treatment of peptic ulcer with HP: 20mg/time x 2 times/day x 7 days. Or 40mg/time x 1 time/day x 10 days; Treatment of gastric ulcer, reflux esophagitis: 20-40mg/time/day x 4-8 weeks; Treatment of peptic ulcers caused by taking NSAIDs: 20mg/time/day x 4-8 weeks; Treatment of Zollinger-Ellison syndrome: Depending on the patient's situation, use; Prophylaxis of ulcers, recurrence of peptic ulcers: 20-40mg/day; How to use the drug:
Esolona should be taken 30-60 minutes before breakfast to inhibit maximum gastric acid secretion. If you have to take the drug twice a day, it is best to take it at least 30-60 minutes before breakfast and 30-60 minutes before dinner. The above dosage is for reference only, the use of the drug needs to be diagnosed and prescribed by the treating doctor.
7. Notes when using Esolona
It is necessary to exclude cases of malignant peptic ulcer before using the drug; Because Esolona is metabolized in the liver, it should be used with caution in people with liver disease; Long-term use of Esomeprazole has the risk of causing atrophic gastritis, so it is necessary to carefully consider the dose and duration of drug use; Esolona may cause adverse effects on the unborn baby; The drug can pass into breast milk, causing unwanted effects on the baby, so breast-feeding should be stopped during treatment with the drug; Because the component Esomeprazole (belonging to the PPI group) is poorly activated when used with other anti-secretory drugs. Therefore, Esolona should not be taken at the same time as other antisecretory drugs. Above is the basic information about the drug Esolona. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Esolona exactly as directed by your doctor, do not increase or decrease your dose or give prescriptions to others for use.
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