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Erilcar is made in the form of tablets with the composition of Enalapril maleate 10mg and excipients just enough for 1 tablet. The drug is mainly used to treat high blood pressure and congestive heart failure.
1. Effects of Erilcar
Erilcar is an angiotensin converting enzyme inhibitor that helps lower blood pressure. After entering the body, the drug has the following effects:For hypertension: Enalapril reduces the total peripheral resistance and with or without increasing heart rate, cardiac output, systolic flow to decrease effective blood pressure. This ingredient in the drug Erilcar mainly has the effect of causing arterial and venous dilation. For congestive heart failure: Enalapril is indicated for use with cardiac glycosides and diuretics, to provide a reduction in peripheral resistance, pulmonary artery pressure, mean arterial pressure, heart size and right atrial pressure.
2. Indications for the use of Erilcar
Erilcar is used to treat hypertension, congestive heart failure and is usually indicated in cases such as:
The degree of patients with essential hypertension; Patients with high blood pressure due to kidney disease. People with high blood pressure and diabetes. Patients with heart failure levels: Improve survival, slow down progression of heart failure, reduce the number of myocardial infarctions; Treatment and prevention of congestive heart failure; Prevention of ventricular dilatation in patients after myocardial infarction; Patients with chronic kidney failure; Prevention of coronary ischemic attack and symptoms of heart failure in patients with left ventricular dysfunction. 3. Contraindications of Erilcar In addition to people who are sensitive to the drug's components, the following cases are contraindicated for treatment with Erilcar:
Patients with angioedema at the beginning of treatment; People with bilateral renal artery stenosis or renal artery stenosis in people with only 1 kidney; Aortic stenosis, severe obstructive cardiomyopathy; Patients with pre-existing hypotension; Children.
4. Dosage of Erilcar
Depending on the patient's health condition, the doctor will prescribe an appropriate and effective dose of Erilcar 5 or Erilcar 10. Some doses of Erilcar can be used as reference for common subjects as follows:
Hypertension patients taking diuretics: Before using Erilcar, the diuretics should be stopped 2-3 days before. If blood pressure has not returned to the desired level, diuretics can be reintroduced cautiously under the direction of the treating physician. In case the patient cannot stop the diuretic, Erilcar 2.5 mg can be used to determine the degree of antihypertensive effect for at least 2 hours and monitor for an additional 1 hour. Patients who have not used diuretics: For adults, the initial dose of Erilcar is 2.5mh/day. For children 1-16 months of age, oral dose of 0.08mg/kg/day, maximum Erilcar 5mg/day, if blood pressure is not responsive enough at the end of the interval between 2 doses when taken once a day, can increase dose or divide into 2 times/day. The patient's dose is adjusted every 2-4 weeks if necessary. In adults, the maintenance dose of Erilcar is 10-40mg/day, taken 1-2 times/day. Children have not been studied with doses exceeding 0.58 mg/kg or exceeding 40 mg. Patients with congestive heart failure can use Erilcar to treat the risk of hypotension with an initial dose of 2.5mg x 1-2 times/day. Use maintenance dose from 5-20mg / day divided into 2 times, the maximum dose for reference is 40mg / day divided into 2 times. Asymptomatic patients with left ventricular dystrophy use the adult initial dose of 2.5mg x 2 times/day, adjusted later on the dose of Erilcar 20mg/day divided into 2 oral doses. Patients with renal failure will have to rely on creatinine clearance, specifically as follows: From 30 - 80ml/min, patients use Erilcar 5mg/day, adjust the maximum dose 40mg. Less than 30ml/min: take Erilcar 2.5mg/day, adjust dosage until blood pressure is controlled. Patients with heart failure with serum creatinine above 1.6 mg/dl or sodium less than 130 mEq/liter: Initial treatment dose is 2.5 mg/day, doubled to a maximum of 40 mg/day if necessary. Patients with hepatic impairment do not need to adjust the oral dose of Erilcar. Erilcar can be taken before or after meals and does not affect the effect of the drug.
5. Erilcar side effects
Erilcar can cause unwanted effects such as:
Dizziness, headache, insomnia, fatigue, paresthesia and dysesthesia. Patients with severe hypotension, orthostatic hypotension, feeling palpitations and chest pain, syncope, angioedema. Manifestations of taste disturbance, vomiting, nausea, diarrhea and abdominal pain. Rash. The patient may have a dry cough. Can lead to kidney failure. Some other less common side effects may occur to patients such as agranulocytosis, neutrophils; proteinuria status; psychomotor agitation; panic attacks and severe depression.
In addition, some rare symptoms in patients using Erilcar are pancreatitis, biliary obstruction, cholestatic toxic hepatitis, oral mucosal sensitization, nasal congestion, blurred vision, muscle pain, bronchospasm, and bronchospasm. , hypersensitivity, asthma ...
6. Precautions when using Erilcar Patients and especially doctors who prescribe drugs should be cautious when using Erilcar in combination with other drugs including:
Antihypertensive drugs, Diuretics and anesthetics: May cause a severe drop in blood pressure in patients. Potassium-sparing diuretics, potassium supplements, potassium-containing salts: May increase blood potassium, especially in patients with renal failure. Lithium: Increases the likelihood that the patient may be poisoned with lithium. Non-steroid anti-inflammatory drugs: May reduce the antihypertensive effect of Erilcar. Contraceptives: Increases the risk of vascular damage and makes it difficult to control blood pressure. Insulin or diabetes medication: Erilcar will lower fasting blood sugar levels, causing hypoglycemia.
7. How to handle an overdose or missed dose of Erilcar 5
When the patient forgets to take Erilcar, it should be taken as soon as he remembers or skip the missed dose if it is almost time for the next dose. Note that the patient should not take a double dose if he or she forgets.
In case of overdose of Erilcar, the patient will have symptoms of severe hypotension, need to immediately stop the drug and go to the nearest medical facility for appropriate and timely treatment support.
8. Note with Erilcar With both Erilcar 5 or Erilcar 10, pregnant women need to be careful because this drug can cause harm or death to the fetus when used by pregnant women. Using Erilcar 5 in the second 2 trimesters of pregnancy causes fetal death and neonatal injury. Therefore, pregnant women are advised not to use Erilcar or when detecting pregnancy to stop the drug as soon as possible.
For mothers who are breastfeeding to ensure the safety of their children, it is necessary to consult a doctor before use to minimize the risk of the drug harming the baby through breast milk.
Patients with heart failure and hyponatremia need medical monitoring and close monitoring of Erilcar dose adjustment.
Some other patients also need to be careful when using Erilcar to treat diseases, namely:
Patients are at risk of non-expressing renal vascular disease. People with the possibility of agranulocytosis when taking ACE inhibitors for people with collagen vascular disease. People who are being treated with diuretics. Patients with hypertrophic cardiomyopathy. People with severe aortic stenosis. People with a history of hereditary or idiopathic angioedema. People with anaphylactic reactions. Patients with impaired renal function. In patients with suspected renal artery stenosis, serum creatinine should be measured before starting treatment. With full information about the drug Erilcar mentioned above, hopefully, it will help patients as well as treating doctors use the drug correctly, effectively and safely.
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