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Efeladin is sold in many pharmacies and hospitals. This is a prescription drug used in HIV patients. Let's learn more about the uses and dosages of Efeladin right here.
1. What is Efeladin?
Efeladin drug belongs to the group of drugs to treat parasites, anti-infectives, antivirals, anti-inflammatory... Efeladin is manufactured by SPM Joint Stock Company (Vietnam), registration number VD -21967 -14.
The main ingredients of Efeladin include:
Lamivudin; Nevirapine; Zidovudine; Primellose; Povidon K30; Avicel M102; Magnesium stearate; HPMC 606; PFG 6000; Titanium dioxide; Talc; Polysorbate 80; Efeladin is available in the form of film-coated tablets. Red white, rectangular feature box. Box of 3 blisters/ 19 tablets or box of 10 blisters/ 10 tablets, box of 1 bottle of 100 tablets.
2. Uses of Efeladin
What does Efeladin do? Efeladin medicine contains main ingredients including Lamivudin, Nevirapin, Zidovudin. These ingredients are all capable of fighting human immunodeficiency virus (HIV).Lamivudin inhibits reverse transcriptase via DNA chain termination; Nevirapine inhibits HIV non-nucleoside reverse transcriptase-1. It binds directly to reverse transcriptase, thereby preventing RNA and DNA-dependent Polymerases from breaking down that enzyme; Zidovudine is a synthetic Nuclroside derivative that inhibits reverse transcriptase across DNA terminators. In general, the drug Efeladin has the main effect of being antiviral. The drug is usually prescribed in cases of HIV-infected patients.
Efeladin drug is not used for subjects who are sensitive to any of the ingredients in the drug. Children under 12 years of age and people with low neutrophils. In addition, the following subjects should not use Efeladin:
Patients with a history of or are suffering from severe liver or kidney failure; Children under 25kg should not take Efeladin; Subjects were previously taking Efeladin but had to stop because of a severe rash. Patients with ASAT or ALAT >5 times the upper limit of normal during Nevirapine use; Patients with abnormal liver function when taking Nevirapine;
3. Dosage and how to use Efeladin
Efeladin is to be taken by prescription. The recommended dose for adults and adolescents (>25 kg) is 2 tablets/day in 2 divided doses.
How to take Efeladin orally. Can be used during or after main meals.
4. Interactions when taking Efeladin
Efeladin medicine contains 3 main ingredients Lamivudin, Nevirapin. Zidovuidine. Therefore, when using, it is necessary to avoid paying attention to interactions with some ingredients such as:
Trimethoripm; Zalcitabine; Fluconazole, Itraconazole, Ketoconazole; Rifabutin, Rifambin, Rifapentin; HIV protease inhibitors; Macrilid group drugs; Non-Nucleoside reverse transcriptase inhibitors; Anti-cancer drugs; Cardiovascular drugs; Birth control pills ; Immunosuppressive drugs, digestive drugs, ..; Inform your doctor about any recent medications you are taking so that appropriate considerations can be made.
5. Effect of Efeladin
Efeladin can cause side effects for users, some side effects can be mentioned as:
Nervous system: headache, fatigue, dizziness, chills, insomnia, trouble sleeping, .. .; Gastrointestinal: vomiting and nausea, diarrhea or dyspepsia flatulence, loss of appetite, abdominal pain....; A cough; Mild to moderate skin rash; Leukopenia, pale skin, anemia; Muscle pain, joint pain ; Side effects when using Efeladin are quite complex and vary from person to person. Immediately notify your doctor if you notice any unusual clinical manifestations.
6. Some notes when using Efeladin
Efeladin should not be combined with Stavudine. In addition, Efeladin may alter liver function. Therefore, when using this drug, it is necessary to conduct blood tests before and periodically for monitoring. Using Efeladin may increase the risk of liver damage. It can even cause death in users. Subjects having problems with red blood cells, white blood cells should be considered when using. Or if used, need to have regular blood tests. Patients who are taking antiretroviral drugs may cause or develop severe degenerative joint disease. Pregnant and lactating women should use caution when taking Efeladin. Share with your doctor for advice on the benefits and risks of taking antiviral drugs. If you are pregnant and taking Efeladin, you need to be monitored regularly. Your doctor may order some other laboratory tests to evaluate each stage. Immune reactivation syndrome can be seen in HIV-infected patients with AIDS, opportunistic infections. You need to inform your doctor about these problems. Efeladin should be stored at an ideal temperature below 30 degrees. Do not leave the medicine in places with too high or too low temperature. Efeladin is a prescription antiviral medication. When using it, it is necessary to be very careful to ensure safety and minimize the risk of side effects. If you have any questions, you should consult your doctor or pharmacist.
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