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Dorobay drug has any effect, can it lower blood sugar? With the main ingredient is Acarbose, Dorobay drug works to reduce blood sugar levels after eating without increasing insulin secretion.
1. What is the effect of Dorobay?
Dorobay belongs to the group of drugs to treat diabetes, with the main ingredient being Acarbose 50mg. Acarbose reduces the risk of postprandial hyperglycemia, but does not cause lactase inhibition and lactose intolerance. Acarbose also does not increase insulin secretion and causes a decrease in fasting blood glucose if taken alone.
In addition, the Acarbose component in Dorobay does not cause calorie loss or weight loss in diabetics and normal people, helping to improve blood glucose control in patients who are not effective when treated with therapies. normally.
Dorobay drug is made in the form of tablets and is indicated for use in the following cases:
Treatment of type 2 diabetes. Supportive treatment in people with postprandial hyperglycemia (single use), when the patient has applied diet and exercise but cannot control it. Treatment of diabetes (in combination with Sulfonylurea) in patients who have been taking Acarbose or Sulfonylurea drugs but not controlled.
2. How to use and dose Dorobay
Dorobay is taken orally. Tablets can be taken with water before meals or chewed with food to lower blood glucose levels after eating.
The goal of Dorobay treatment is to lower postprandial blood glucose and bring hemoglobin glycosylate values to near normal or normal levels.
After eating about 1 hour, it is necessary to measure the blood glucose concentration to determine the patient's ability to respond to Dorobay, thereby adjusting the dose accordingly. Patients should also be monitored for hemoglobin glycosylate every 3 months to assess long-term blood sugar control.
Dosage of Dorobay is as follows:
Starting dose: 25mg/time, 3 times/day. May start with a dose of 25mg once a day to reduce the side effects of the drug on the digestive system. Then, if the patient can tolerate the drug, increase the dose gradually up to 3 times/day. Maintenance dose: 50-100mg/time, 3 times/day. Based on blood glucose levels measured 1 hour after eating, adjust dose every 4 to 8 weeks. The maximum dose of Dorobay is determined depending on the weight as follows:
Under 60kg: 50mg/time, 3 times/day. Over 60kg: 100mg/time, 3 times/day. The maximum dose can be up to 200mg / time and taken 3 times / day. Reduce dose of Dorobay in case serum glucose after meals or hemoglobin glycosylate value does not decrease even though the patient has taken 200mg/time, used 3 times/day. The maintenance dose should be a dose that is tolerable and effective for the patient.
In all cases, it is best for the patient to consult a doctor to be prescribed the appropriate dose of Dorobay.
Dorobay overdose can cause symptoms such as abdominal pain, diarrhea, bloating, but these symptoms go away quickly. When overdose, within 4-6 hours, the patient should not eat or drink foods containing a lot of carbohydrates.
3. Dorobay side effects
Dorobay medicine can cause some unwanted side effects with the frequency of occurrence as follows:
Common: Abdominal pain, diarrhea, flatulence. Uncommon: Indigestion, nausea, vomiting, increased liver enzymes. Rare: Angioedema, jaundice. Frequency not known: It is not known how often Dorobay causes thrombocytopenia, hypersensitivity reactions such as urticaria, rash, skin erythema, hepatitis, intestinal obstruction, flatulence, generalized pustular syndrome acute body. Often, side effects can be reduced by reducing sugar intake even as the patient continues to take Dorobay. If there are strange symptoms after taking Dorobay, for unwanted effects in the digestive system, patients need to take the drug with the lowest dose, then gradually increase the dose until the desired results are achieved. would like. Note, patients should not take any antacids to treat side effects encountered in the digestive system.
For liver / biliary damage caused by Dorobay drug such as jaundice, increase in serum aminotransferase, after stopping the drug, these lesions will disappear.
4. Some notes when using Dorobay
Do not use Dorobay in people with hypersensitivity to the ingredients of the drug, people with severe renal failure with creatinine clearance less than 25ml/min, pregnant or lactating women, children under 18 years old. Do not use Dorobay in people with digestive diseases such as gastrointestinal disorders accompanied by enteritis; malabsorption (such as ulcerative colitis); partial intestinal obstruction (or at risk of bowel obstruction); Gastric hyperplasia (eg, intestinal ulceration, intestinal obstruction, severe hernia, Roemheld syndrome). Concomitant administration of Dorobay with other hypoglycemic agents may cause excessive hypoglycemia. Use oral glucose instead of sucrose because Dorobay may slow digestion and absorption of disaccharides. Liver enzymes should be monitored during 6-12 months of taking Dorobay because the drug can trigger a flare-up of hepatitis that causes liver damage. Reduce dose or may discontinue drug in case of elevated liver enzymes, monitor for several weeks until normal values are reached. Do not use antacids containing magnesium or aluminum to treat acute gastrointestinal symptoms experienced with Dorobay. The toxicity and safety of the drug in pregnant or lactating women is limited. Therefore, do not use the drug in this group of subjects. While taking Dorobay, if you consume a lot of food containing the white sugar sucrose, you have a higher risk of abdominal pain and diarrhea due to increased carbohydrate fermentation in the colon. Dorobay may interfere with the absorption or metabolism of iron if taken concomitantly with iron-containing products. Concomitant administration of Dorobay with other antidiabetic agents may increase the hypoglycemic effect; with antacids can reduce the effect of the drug Dorobay; with Neomycin increases the hypoglycemic effect; reduce the effect of digoxin. The use of Dorobay drug is to reduce blood sugar after eating in people with type 2 diabetes or in cases of using the drug alone, in combination or having applied other therapies such as diet, exercise but cannot control it. control blood sugar. To ensure safety for health and maximize the effectiveness of treatment, patients need to take Dorobay medicine exactly as directed by the doctor.Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
