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Domitral 2.5mg medicine contains the main ingredient Nitroglycerin, which is effective in the treatment and prevention of angina pectoris, severe total or left-sided heart failure. Compliance with indications, dose of Domitral 2.5mg will help patients improve treatment effectiveness and avoid unwanted side effects.
1. What is Domitral 2.5 mg?
Domitral 2.5 mg belongs to the group of cardiovascular drugs, in the form of capsules. The main ingredient in the drug Domitral 2.5 mg is Nitroglycerin, which is effective in preventing angina pectoris, adjuvant treatment in severe total or left-sided heart failure. The active ingredient Nitroglycerin is less effective when taken orally because it is hydrolyzed in the stomach and degraded strongly by the liver. Domitral 2.5 mg drug takes effect after 20-45 minutes and lasts 7 hours.
2. Dosage and administration of Domitral 2.5 mg
How to take Domitral 2.5 mg:
Take Domitral 2.5 mg tablet whole with a full glass of water, do not chew, crush or suck on the tablet. Dosage reference:
Prevention of angina: Dose 2 - 3 tablets 2.5mg/day, divided into several times a day. Treatment of congestive heart failure (in combination with other drugs): In chronic heart failure, the dose is 2.5mg/time, 2-5 times/day. Note: Domitral 2.5 mg dosage above is for reference only. The specific dose of Domitral 2.5 mg depends on the condition and the progression of the disease. To get the right dose of Domitral 2.5 mg, patients should consult their doctor or healthcare professional.
3. Management of missed dose, overdose Domitral 2.5 mg
3.1. Domitral 2.5 mg Overdose Nitroglycerin overdose can lead to the following symptoms:
Severe hypotension; Cardiovascular collapse, syncope; severe headache, dizziness; Visual disturbances; Increased intracranial pressure; Nausea and vomiting; Abdominal pain, diarrhea; Shortness of breath, paralysis, coma. Treatment of drug overdose:
Put the patient in a lying position, raise the legs to improve the amount of blood returning from the veins; Give fluids to the patient and make sure the airway is clear; Do not use vasoconstrictors because they will cause more harm; When methemoglobinemia occurs, it should be treated by injection of methylene blue solution; Perform gastric lavage for the patient early, if the drug is to be administered via the gastrointestinal tract. 3.2. Missed dose of Domitral 2.5 mg In case of forgetting a dose of Domitral 2.5 mg, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and use a new dose. Do not take a double dose to make up for a missed dose of Domitral.
4. Side effects of Domitral 2.5 mg
When using Domitral 2.5mg, patients may experience the following side effects:
Common: Headache, dizziness, tachycardia, hypotension, facial redness, allergic dermatitis; Uncommon: Nausea and vomiting; Rare: Cyanosis, methemoglobinemia, loss of taste and fainting. If you experience any of these symptoms, you should stop using Domitral 2.5 mg and notify your doctor or pharmacist for appropriate treatment.
5. Contraindications to Domitral 2.5 mg
Domitral 2.5mg is contraindicated in the following cases:
Allergy to organic nitrates; People with low blood pressure, cardiovascular collapse; Severe anemia, increased intracranial pressure due to trauma or cerebral hemorrhage. Right ventricular myocardial infarction. Obstructive hypertrophic cardiomyopathy; Aortic valve stenosis; Constrictive pericarditis; Closed angle glaucoma.
6. Drug interactions
When taking Domitral 2.5 mg, patients should not drink alcohol because it can cause serious damage to blood pressure. Antihypertensives, diuretics and vasodilators can all potentiate the hypotensive effect of nitroglycerin, especially in the elderly. Above is information about the uses, dosage and precautions when using Domitral 2.5 mg. To ensure the safety of your health and maximize the effectiveness of treatment, you need to take the medicine exactly as directed by your doctor.
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