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Diflucan 150mg is an antifungal medicine. Fluconazole is used to treat and prevent many types of fungal infections. The drug has quite strong medicinal properties, so to ensure the safety and effectiveness of treatment, patients need to carefully learn about the product information and use it according to the prescribed dose.
1. What is Diflucan 150mg?
Diflucan 150mg is the name of an azole antifungal medicine. With the main ingredient is Fluconazole 150mg content to effectively treat fungal infections. Medicines can only be used and sold with a doctor's prescription. In addition to the main ingredient Fluconazole, the drug also has excipients Lactose monohydrate, sodium lauryl sulphate, patent blue V (E131), colloidal anhydrous silica, gelatin, corn starch, magnesium stearate, titanium dioxide (E171).2. How does Diflucan 150mg work?
Fluconazole ingredient in Diflucan 150mg drug inhibits cytochrome P450-14-α-demethylase enzyme, while Difuzit prevents the self-synthesis of sterols in the membranes of fungal cells. As a result, it changes the permeability of the membrane, so that from the side of the membrane, the biological substances are easily released, and this process also hinders the ability of the fungal cells to absorb many substances. Therefore, the drug Diflucan 150mg is used to treat cases of fungal infections.
3. Indications and contraindications of Diflucan 150mg
3.1 Indication Diflucan 150mg is a brand name drug with high medicinal properties, so it is indicated for use in some cases such as:
Treatment of recurrent and acute vaginal candidiasis (vaginal and vulvar) Treatment of skin candidiasis (fungus in any part of the head, hands, feet, whole body, inguinal fungus, skin candidiasis) Treatment of ringworm and tinea versicolor Treatment of nail fungus, skin fungus. Meningitis caused by strains of Cryptococcus neoformans, Treatment and prevention of Candida infections in cases of malignancy, critical illness, marrow transplantation, radiation therapy, or immunodeficiency, cancer, AIDS. 3.2 Contraindications Similar to other antifungal and antiviral drugs, Diflucan 150mg is contraindicated for:
People who are sensitive or allergic to drug components. Pregnant women and mothers who are breastfeeding.
4. Usage and dosage of Diflucan 150mg
Diflucan 150mg medicine is prepared in the form of long capsules covered with hard gelatin and administered orally. Patients can take the drug at any time of the day, but it is recommended to take it after meals. The duration of drug therapy depends on the type of fungal disease, the cause, the response to the drug and kidney function. In order not to affect the treatment results, the patient should continue to use it until the doctor's conclusion is completely cured. Because if not treated thoroughly, it will make the disease worse and more difficult to treat.
Dosage:
Newborns < 2 weeks: 3 - 6 mg/kg body weight x 3 days/time.
Newborns > 2 weeks: 3 to 6 mg/kg body weight 2 times a day x 2 days/time.
Children: Drink once a day.
Prophylaxis: 3mg/kg body weight/day (superficial fungal infections) and 6-12mg/kg body weight/day (systemic fungal infections). Treatment: 6mg/kg body weight/day, the dose can be increased if the severity is severe, but do not use more than 600mg/day. Adults:
Vaginal candidiasis (vulva-vaginal): 1 tablet/day, to cure and prevent re-infection, it is necessary to maintain it continuously for 4 to 12 months. Mucosal candidiasis (oral - pharynx): 1 tablet/day, maintained for about 7 to 14 days. Esophageal fungal infections: 1 tablet/day, maintained for at least 3 weeks. After the symptoms are gone, use another 14 days to prevent recurrence. Systemic fungal infections: 3 tablets/day first, the next day maintain 1 tablet/day. Drink at least for 1 month. In order for the disease to completely heal and not recur, it is necessary to take another 7 days. Meningitis patients: 3 tablets/day first, the next day maintain from 1 to 3 tablets and maintain for 6 to 8 weeks. Patients infected with HIV/AIDS: 1 tablet/day, continuously maintained until prescribed by a doctor. Prophylaxis against fungal infections in bone marrow transplant recipients, cancer patients, and tumors: 3 tablets/day. The dosage information above is for reference only. Because the specific dose depends on the condition of the disease and age. Therefore, to ensure the highest safety and effectiveness of treatment, you should visit a doctor for appropriate prescription.
5. Note to use Diflucan 150mg
Before using drugs to treat diseases, users need to pay attention to some of the following contents:
Read carefully the information related to the product. Carefully read the manufacturer's information on the product description on the packaging. The drug is indicated by oral administration directly with filtered water, without arbitrarily changing the way of taking or dosage. Prescribe with caution in special cases such as impaired liver and kidney function, heart arrhythmias, low blood pressure, etc. Although, currently, there are no specific research reports on Diflucan 150mg causing drugs. teratogens or affect the quality of breast milk, but can not be used at risk. The drug causes some side effects such as drowsiness, dizziness, headache, so it can be dangerous for people who are operating, going out, working, driving or exercising. Do not drink alcohol while taking the drug. Consult your doctor before taking the medicine.
6. Side effects when using Diflucan 150mg
During the use of Diflucan 150mg, patients may experience a few side effects such as:
Common:
Liver: increased liver enzymes, pale yellow skin. Digestive system: nausea, taste disturbance, abdominal pain, flatulence, diarrhea, .... Capillaries: Dizziness, thrombocytopenia - white blood cell, headache, high blood lipid. Rare:
Skin: Peeling skin, toxic epidermal necrolysis,... Stevens-Johnson syndrome. Angioedema and anaphylaxis. Hair loss: when treated for a long time, the possibility of hair loss is much and difficult to control. When you have any of the above abnormal symptoms, the patient should immediately notify the doctor for timely treatment.
7. Drug interactions
Interactions may occur if Diflucan 150mg is used concurrently with some drugs such as:
Rifampicin: reduces fluconazole plasma concentrations. Hydrochlorothiazide: Increases fluconazole plasma concentrations. Ciclosporin, phenytoin, nortriptylin, midazolam, rifabutin, nateglinide, triazolam, tacrolimus, sulfonylurea and nateglinide hypoglycemic agents, warfarin and zidovudine: increase fluconazole plasma concentrations. Sulfamethoxazole: easy to cause poisoning. Terfenadine: lead to ECG abnormalities. Cisapride: increases the concentration of cisapride and causes toxicity. Astemizol, terfenadine, cisapride: arrhythmia. Amitriptyline: increased concentration of amitriptyline itself. Steroid contraceptives: affect the effectiveness of contraception. Patients should actively provide their doctor or pharmacist with a list of drugs or supplements that are currently using or want to use. This is the best solution to avoid interactions. However, if during the course of taking the drug, the body has abnormal signs as mentioned above, please calmly contact your doctor or visit the nearest medical facility to be diagnosed and given an appropriate regimen. fit.
8. Instructions on how to best manage overdose and missed doses.
Missed dose: Take it as soon as you remember, but if it's the same or close to the next dose, skip the missed dose and take a new dose. Do not arbitrarily add dose by planting dose, Overdose: Stop using and immediately go to the nearest medical facility for quick treatment. In short, Diflucan 150mg is a prescription oral antifungal drug. Fluconazole is used to treat and prevent many types of fungal infections. The drug has quite strong medicinal properties, so to ensure the safety and effectiveness of treatment, patients need to carefully learn about the product information and use it according to the prescribed dose.
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