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Davicum medicine containing Vipocetin active ingredient is indicated in the treatment of chronic disorders of the retina and choroidal vessels, hearing loss in old age, disorders of cerebral blood circulation... Let's learn about the uses and notes when Use the drug Davicum through the article below.
1. Uses of the drug Davicum
"What does Davicum do?". Davicum drug containing active ingredient Vinpocetin 10mg/2ml is prepared in the form of solution for infusion. Davicum is indicated in the following cases:
Neurological: Acute and chronic cerebrovascular insufficiency (ischemic stroke, transient ischemic attack, pre-stroke state and after brain injury, cerebral atherosclerosis, memory loss due to multiple cerebral infarction, weakening of the spine base, psychiatric symptoms of stroke; Eye: Corolla or retinal spasm cause appearance ophthalmic (including arterial occlusion, macular degeneration, embolism or secondary glaucoma); Ear: Deafness in old age, hearing loss (due to drugs and other causes), Méniere's disease, vertigo facial, vestibular cochlear neuritis, spontaneous hearing in the ear.
2. Dosage of the drug Davicum
Davicum is administered by slow intravenous infusion, the infusion rate does not exceed 80 drops/min. Note: Do not use the drug by subcutaneous injection, rapid intravenous injection or intramuscular injection.
The recommended dose of Davicum for adults is 20mg of Vinpocetine in 500-1000ml of solution for infusion. In case the patient responds well, the dose should be repeated 2-3 times/day at a slow infusion rate, the dose may be increased over 3-4 days to a maximum of 1mg/kg/day. The interval between courses of treatment with Davicum is 10-14 days, the average daily dose is about 50mg/70kg body weight. No dose adjustment is required in patients with hepatic or renal impairment.
The infusion solution that can be used is 0.9% sodium or divided glucose in the solution of Rindex, Salzol, Rheomacrodex... Vinpocetine infusion solution can be used for 3 hours after surgery.
3. The effect of the drug Davicum
Davicum medicine may cause some unwanted effects as follows:
On the senses and nervous system: Dizziness, sleep disturbances, fatigue, headache, excessive sweating, feeling of fever (symptoms). this symptom may be a hidden sign of disease); Cardiac: QT interval prolongation, ST segment lowering, extrasystoles and tachycardia; On the vascular system: Change in arterial pressure, phlebitis, skin flushing, agranulocytosis; On the digestive system: Nausea, dry mouth, heartburn; On the skin: Excessive sweating; On the immune system: Hypersensitivity reactions. Patients need to stop using Davicum and notify the treating doctor in case of any unwanted effects.
4. Note when using the drug Davicum
4.1. Contraindications Contraindicated to use Davicum drug in the following cases:
Patients with hypersensitivity to Vinpocetin or any component of the drug Davicum; The patient has had an acute or recently recovered hemorrhagic stroke; Patients with arrhythmia, severe myocardial ischemia, high intracranial and intraocular pressure; Pregnant women, lactating women and children. 4.2. Precautions for use Caution when using Davicum in the following cases:
Patients with increased intracranial pressure, abnormal heart rhythm, prolongation of the QT interval or being treated with antiarrhythmic drugs; Patients with unstable blood pressure, unknown pulse; Use with caution in patients taking antihypertensive drugs as well as patients with little response to drugs derived from periwinkle alkaloids and patients with impaired liver function.
5. Drug interactions
Concomitant use of Davicum with beta-blockers (Pindolol, Chloranolol), Glibenclamide, Acenocoumarol, Digoxin or Hydrochlorothiazide showed no synergistic effects or interactions between drugs.
Concomitant use of Davicum and Alpha-Methyldopa may lower blood pressure to some extent. Therefore, during treatment, patients need to regularly monitor arterial blood pressure.
Drug interactions occur to reduce the therapeutic effect of Davicum, increase the risk of unwanted effects. Therefore, to ensure safety and effectiveness, patients need to inform their doctor of all drugs and supplements before being treated with Davicum. Davicum contains Vipocetin active ingredient, which is indicated in the treatment of chronic disorders of the retina and choroidal vessels, hearing loss in old age, disorders of cerebral blood circulation. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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