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Danalax has the main active ingredient is Bisacodyl which has a laxative effect. It is used to treat constipation or to clear the colon before a procedure or surgery. The article will provide information about the uses, dosage and notes when using Danalax.
1. What is Danalax?
Danalax has the main active ingredient Bisacodyl, a derivative of Diphenylmethane, which has a stimulant laxative effect and is used for short-term treatment of constipation or to cleanse the colon before procedures or surgery.Bisacodyl has the effect of stimulating the nervous plexus in the intestine (mainly in the colon), so it acts directly on intestinal smooth muscle, increasing colonic motility and reducing constipation. Besides, the drug also helps to increase electrolytes and fluid in the colon, causing a laxative. Bisacodyl is poorly absorbed following oral administration. After oral administration, Bisacodyl begins to work within 6 - 10 hours.
2. Uses of Danalax Drug Danalax is indicated in the treatment of constipation (idiopathic, drug-induced or irritable colon syndrome), bowel cleansing before and after surgery or colon preparation before X-ray.
Danalax is contraindicated in patients with acute intra-abdominal surgical diseases, intestinal obstruction, appendicitis, rectal bleeding, acute enteritis (ulcerative colitis, Crohn's disease) and dehydration heavy.
3. Dosage of the drug Danalax Danalax is used orally. Patients should not chew Danalax tablets before taking
Treatment of constipation:
Adults and children over 10 years old: It is recommended to take a single dose of 5 - 10mg (can be increased to 15mg) in the evening. Colon preparation before X-ray or surgery:
Adults and children over 10 years: 10 - 20mg is recommended the evening before the procedure. Then 1 10mg rectal suppository the next morning, before the scan or surgery.
4. What are the side effects of Danalax?
Patients using Danalax drug may experience undesirable effects including:
Common:
Gastrointestinal: Abdominal pain, nausea, vomiting and diarrhea. Endocrine and metabolic: Dehydration and electrolyte imbalance. Uncommon:
Long-term use of Danalax can cause colon atony. Hypokalemia and hypocalcemia. Patients should notify their doctor when experiencing unusual side effects.
5. Precautions when using the drug Danalax Danalax film coated tablets are manufactured to dissolve only in the intestine, so do not chew the medicine before taking it. Patients need to use antacids and milk at least 1 hour away from Danalax. Long-term use of Danalax can lead to drug dependence, colon atony, and fluid and electrolyte disturbances. Therefore, laxatives should be avoided for more than 1 week, unless directed by a doctor. The use of stimulant laxatives should be avoided in children under 6 to 10 years of age. Pregnancy: There are currently insufficient data on the use of Danalax in pregnant women. In clinical, there are not enough data to evaluate whether Danalax is malformative or toxic to the fetus. Therefore, Danalax should not be used by pregnant women. If you must use it, monitor it carefully. Lactation: Danalax passes into breast milk in small amounts. Therefore, extreme caution must be exercised when administering the drug to a nursing mother. Overdose and management: Rare cases of overdose Danalax drug. Symptoms of Danalax overdose include abdominal pain, which may be accompanied by signs of dehydration, especially in the elderly and children. Patients may also have muscle weakness, metabolic acidosis, and hypokalemia. There is no specific antidote for Danalax intoxication. Treatment is gastric lavage, maintenance of rehydration and monitoring of serum potassium. Antispasmodics may be of value in this case. Pay special attention to fluid balance in the elderly and young children.
6. Drug interactions
Concurrent use of Danalax with some other drugs may cause interactions, affect the effectiveness of treatment or increase toxicity. The following are some drug interactions to note when using Danalax:
Avoid combining Danalax with drugs that have a risk of causing torsades de pointes such as: Amiodarone, Bepridil, Bretylium, Disopyramid, Intravenous Erythromycin, Pentamidine, Quinidin, Sparfloxacin, Sotalol and Terfenadin. Because of the increased risk of ventricular arrhythmias, especially torsades de pointes. Glycosides: Caution should be exercised when Danalax is co-administered with cardiac glycosides because of the risk of hypokalemia, which may increase the toxic effects of cardiac glycosides. Blood potassium should be monitored and an electrocardiogram performed if necessary. Drugs that cause hypokalemia such as diuretics, intravenous amphotericin, systemic corticosteroids can have additive effects that increase the risk of hypokalemia. Using Danalax in combination with antacids, H2-receptor antagonists such as Cimetidine, Famotidine, Ranitidine and milk within 1 hour will make the stomach and duodenum irritated because the drug is dissolved too quickly. Therefore, the above drugs should be taken at least 1 hour apart. Above is all information about the drug Danalax, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Danalax treatment at home because there may be unwanted side effects.
