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Daklife belongs to the group of cardiovascular drugs, effective in primary prevention of disorders caused by thromboembolism. What precautions should patients take when using Daklife? Let's find out information "What is Daklife?" through the following article.1. What is Daklife?
Daklife belongs to the group of cardiovascular drugs, indicated in the primary prevention of thromboembolic disorders, control and secondary prevention in patients with atherosclerotic recent stroke. Daklife has the main active ingredient Clopidogrel (as Clopidogrel bisulfate) 75mg and excipients just enough for 1 tablet.Daklife medicine is prepared in the form of film-coated round tablets, packed in a box of 3 blisters, 10 blisters, 20 blisters x 10 tablets.
2. What are the effects of Daklife?
Daklife drug is indicated in the following cases:
Primary prevention of thromboembolic disorders such as myocardial infarction, stroke and peripheral arterial disease. Control and secondary prevention, in atherosclerotic patients with recent myocardial infarction or confirmed peripheral arterial disease. Treatment of patients with acute coronary syndrome (unstable angina/non-Q wave myocardial infarction).
3. How to use Daklife thuốc
3.1. How to use Daklife drug For Daklife drug, patients use it orally. Daklife can be taken with or without food.
3.2. Dosage of Daklife The recommended dose of Daklife is as follows:
Patients with a history of atherosclerosis: Use a dose of 75mg (1 tablet)/day. Prophylaxis against thromboembolism (myocardial infarction, peripheral artery disease and stroke): 75mg (1 tablet)/day. Patients with acute coronary syndrome (unstable angina/non-Q-wave myocardial infarction): Initial dose of 300 mg as a single dose. Maintenance dose is 75mg (1 tablet)/day. Patients with renal impairment and the elderly: It is not necessary to adjust the dose of Daklife. 3.3. How to deal with forgetting, overdose Daklife medicine Missed dose:
There are no documents showing the disadvantage of forgetting a dose of Daklife. However, to ensure the most accurate drug effect, patients need to use the full therapeutic dose as directed by the doctor.
Overdose:
Daklife overdose leads to prolonged bleeding time, followed by bleeding complications. Other symptoms are vomiting, fatigue, shortness of breath, and gastrointestinal bleeding. Patients should immediately notify the treating physician if there is any suspicion of an overdose of Clopidogrel.
3.4. Contraindications to Daklife: Contraindicated to use Daklife in the following cases:
Patients with allergies, hypersensitivity to Clopidogrel or any of its ingredients. Patients with bleeding disorders such as gastrointestinal ulcers or bleeding in the brain. Patients with severe liver failure.
4. Notes when using Daklife
Warnings and cautions when using Daklife: Be careful when using Daklife in patients with bleeding due to trauma, surgery or other diseases. Discontinue use of Daklife for 5 days in patients preparing for surgery. Daklife should be used with caution in patients with bleeding-prone lesions. Use with caution in patients with hepatic impairment, patients with changes in metabolism (poor metabolism due to CYP2C19). Patients should be informed that they are prone to bruising and prolonged bleeding while taking Clopidogrel. Daklife contains lactose. Therefore, caution should be exercised in patients with rare hereditary problems of galactose intolerance, lactase deficiency or glucose-galactose malabsorption. For women who are pregnant or breast-feeding: There are no adequate studies on the use of this drug in this population. The drug should only be used with the approval of a doctor and the benefits/risks to mother and baby need to be weighed. Children and Adolescents: There are no data on the safety and efficacy of this drug in pediatric and adolescent patients. Driving and using machines: Clopidogrel has no influence on the ability to drive and use machines. Side effects when using Daklife: When using Daklife, patients may experience the following undesirable effects:
Digestive disorders: Abdominal pain, vomiting, loss of appetite, gastritis and constipation . Cardiovascular: Angioedema, hypertension, chest pain, atrial fibrillation, heart failure, syncope. Nervous system: Dizziness, headache, body aches, fever, anxiety. Skin: Erythema, pruritus, eczema. Endocrine and metabolic: Increased cholesterol, uric and blood gout. Urinary tract infections, cystitis. Hematology: Nosebleeds. Liver: Abnormal liver function. Muscles and bones: Joint pain, back pain, cramps, muscle weakness. Pseudo-flu syndrome. Eyes: Conjunctivitis and cataracts. Interactions and incompatibilities Daklife: Caution when combining Acetylsalicylic acid, Heparin and Clopidogrel: May increase the risk of bleeding. Proton pump inhibitors that may interact with Clopidogrel: Decrease concentrations of the active metabolite clopidogrel and decrease antiplatelet effect. Non-steroidal anti-inflammatory drugs have been shown to increase occult gastric bleeding when used concomitantly with naloxone and clopidogrel in healthy subjects. Caution should be exercised when clopidogrel is co-administered with glycoprotein receptor blockers because of the increased risk of bleeding from trauma, surgery, or other conditions. Clopidogrel inhibits the metabolism of the CYP2C19 isoenzyme, resulting in increased concentrations of the following drugs: Phenytoin, Warfarin and non-steroidal anti-inflammatory drugs. CYP2C19 inhibitors such as omeprazole, cimetidine, fluconazole and ketoconazole may decrease the plasma concentrations of the active metabolite of clopidogrel and reduce the antiplatelet effect. Daklife drug storage: Store Daklife medicine at a temperature below 30°C. Keep the medicine in a closed container, in a cool, dry place, away from moisture and avoid direct sunlight. Carefully read the instructions for storing Daklife medicine listed on the package. Above is all necessary information when using Daklife medicine. Daklife is a prescription drug, users are not allowed to use it without consulting a doctor.
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