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Dagroc is an ETC drug, manufactured by MeDiSun Pharmaceutical JSC, used in the treatment and prevention of progression for benign prostatic hyperplasia. To learn more about the uses, usage and important notes of Dagroc, please read and follow the following article.
What is Dagroc?
Dagroc drug is in the form of soft capsules, light yellow color, light fragrance, inside contains colorless clear liquid.
Classification: ETC drugs - prescription drugs. Ingredients: Dutasteride 0.5mg, Absolute Ethanol, Sorbitan oleat, Macrogolglycerol hydroxystearate 20, Gelatin, Glycerin, Polyethylene glycol 300, ethanol 96%, Potassium sorbate, Titanium dioxide, distilled water, iron oxide yellow. Packing: Packed in a box of 3 blisters x 10 tablets. Registration number: VD-25056-16. Manufacturer: MeDiSun Pharmaceutical Joint Stock Company - Vietnam.
Uses of Dagroc
Dagroc is highly effective in the treatment and prevention of the development of benign prostatic hyperplasia (BPH-Benign Prostatic Hyperplasia), thanks to its symptom-reducing action and the size (volume) of the gland. prostate. It also improves urine flow and reduces the risk of acute urinary retention (AUR) and reduces the need for surgery related to BPH.
On the other hand, dutasteride can also be used alone or in combination with alpha-blockers in the treatment and prevention of the development of benign prostatic hyperplasia (BPH).
3. Dosage and usage
3.1. Dosage
For adults (including the elderly): The recommended dosage is 1 capsule 1 time per day. Although the drug may produce an early response, it may still require treatment for at least 6 months, to most objectively assess the likelihood of a desired response to treatment. For the treatment of benign prostatic hyperplasia, patients can use it alone or in combination with the alpha blocker tamsulosin (0.4 mg). For patients with renal impairment: There are currently no studies showing the effect of renal impairment on the pharmacokinetics of Dagroc. However, no dose adjustment of dutasteride is required in this patient population. For patients with hepatic impairment: The effect of hepatic impairment on the pharmacokinetics of dutasteride has not been studied. 3.2. How to use Dagroc drug is prepared in the form of folliculitis, so the patient should swallow the capsule whole, do not chew or open the tablet. Contact with the contents of the capsule may cause irritation of the oral mucosa - oropharynx. Patients can take the drug with or without meals.
3.3. Dealing with missed dose, overdose
Missed dose:
When you forget a dose, you should take it as soon as you remember it (about 1-2 hours). However, if it is too close to the time of remembering to take the next dose, we can skip the missed dose and take the next dose as scheduled.
Overdose:
According to clinical studies in volunteers, when dutasteride was taken at doses up to 40 mg/day (80 times higher than treatment) for 7 days, no significant concerns about Safety..
According to clinical studies, if patients use Dagroc at a dose of 5mg per day for 6 consecutive months, the results do not have any additional unwanted side effects. Treatment dose 0.5mg
Currently there is no specific antidote for dutasteride, so in case of suspected side effects due to overdose, the patient should conduct symptomatic treatment and contact the doctor at the same time. doctor for appropriate supportive measures.
4. Note when using
4.1. Contraindications
Dagroc is contraindicated in the following cases:
Hypersensitivity or allergy to any active ingredients, excipients in the drug. The patient has been suffering from liver disease or prostate cancer. Women who are breastfeeding or are pregnant, limit use for young children (only use when prescribed and directed by a doctor). In particular, pregnant women should avoid contact with the drug capsule, in case of contact with the inner components of the drug, should quickly wash the contact area and notify the doctor immediately. People planning to donate blood. 4.2. Side effects In the process of using Dagroc, patients may experience a few unwanted side effects such as:
Decreased sex drive in men, decreased both quality and quantity of sperm. Causes breast enlargement, breast pain due to hormonal changes in men. Occurrence of some allergic phenomena such as: itchy rash, red swelling, rash, swelling of throat, lips and tongue... Rarely, hirsutism and hair loss (mainly body hair loss) . When experiencing these phenomena, the patient should immediately contact a medical agency or a specialist for support and instructions on how to remove them safely.
4.3. Drug Interactions Dagroc may interact with:
Conivaptan (Vaprisol). Imatinib (Gleevec). Isoniazid (treatment of tuberculosis). Antibiotics such as erythromycin (EES, EryPed, Ery-Tab, Erythrocin, Pediazole) clarithromycin (Biaxin) or telitromycin (Ketek). antifungal medicines such as voriconazole (Vfend), ketoconazole (Nizoral), miconazole (Oravig), or itraconazole (Sporanox). Antidepressants such as nefazodone. heart or blood pressure medications such as quinidine (Quin-G) or nicardipine (Cardene). HIV/AIDS medicine such as saquinavir (Invirase), delavirdine (Rescriptor), atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), or ritonavir (Norvir, Kaletra). The above list of interacting drugs is not complete and there are still other products that can interact with Dagroc. Therefore, tell your doctor about all medications (prescription and non-prescription), supplements, vitamins or herbs that you are taking.
To ensure safety and effectiveness when using Dagroc, patients should consult and use it exactly as prescribed by a specialist.
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