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Cotrimnicpharma is a drug containing the active ingredient Trimethoprim and Sulfamethoxazol as the main ingredient. The following article will introduce the uses and some notes when using Cotrimnicpharma drugs.1. What is Cotrimnicpharma?
Cotrimnicpharma is a drug containing the main active ingredient 160mg Trimethoprim and 800mg Sulfamethoxazol. In which:Trimethoprim is a bacteriostatic drug with the role of inhibiting the enzyme dihydrofolate - reductase of bacteria. Trimethoprim against pathogens in the urinary tract such as E.coli, Klebsiella, Proteus, Enterobacter, Streptococcus faecalis... Sulfamethoxazole is a sulphonamide capable of combining with trimethoprim in the ratio 1:5 to help create synergistic effects. Enhanced copper increases the effectiveness of treatment and reduces drug resistance. Sulfamethoxazole is structurally similar to para aminobenzoic acid (PABA) and through competition with PABA for its high affinity for dihydropteroate synthetase to inhibit phase I of bacterial folic acid synthesis.
2. Effects of the drug Cotrim Nic Pharma
Cotrimnicpharma drugs are used in the following cases:
Broad-spectrum treatment of infections caused by Gram (-) and Gram (+) bacteria. Especially in cases of gonococcal infections, uncomplicated acute urinary tract infections and patients with Pneumocystis carinii pneumonia. Infections caused by microorganisms susceptible to sulfamethoxazole and trimethoprim Cases of respiratory tract infections such as exacerbations of chronic bronchitis.
3. Instructions for using Cotrim Nic Pharma
The drug is used orally with different doses depending on the condition of the disease:
Urinary tract infections: Take 1-2 tablets of 480mg * 2 times a day, lasting for 10 days. Respiratory tract infections: Take 1-2 tablets of 480mg* 2-3 times a day, lasting for 10 days. days, lasting for 5 days.
4. Some notes when using Cotrim Nic Pharma drugs
When using Cotrimnicpharma for pregnant women, it can cause adverse effects such as miscarriage, fetal malformation, teratogenicity in any stage of pregnancy development. Therefore, this drug should not be used by pregnant women. If necessary, consult a doctor before use. Some rare side effects when using the drug include gastrointestinal disturbances, skin reactions, stomatitis, erythema multiforme, tinnitus, Stevens-Johnson syndrome, Lyell, neutropenia, and urinary retention. bridge.
The drug can cause an interaction reaction when used at the same time with the following drugs: thiazide diuretics, warfarin, methotrexate, phenytoin, hypoglycemic agents, pyrimethamine, indomethacin, cyclosporin.
The above are the uses of Cotrimnicpharma, understanding the ingredients and mechanism of action will help the drug process be more effective. If you have any further questions, the patient should directly discuss with the prescribing physician for appropriate indications.
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