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Clazidyne with the main ingredient is Loratadin, belongs to the group of anti-allergic drugs, used in cases of hypersensitivity and allergies. Find out more information about the drug Claazidyne through the article below.
1. What is Claazidyne?
Clazidyne brand name drug of Loratadin , belongs to the group of 2nd generation antihistamines, H1 receptor antagonists. Loratadine is a long-acting tricyclic antihistamine, a selective second-generation peripheral H1-receptor antagonist, with no sedative effect, no appreciable muscarinic activity, and no sedative effect. on the central nervous system. Loratadine, when entering the body, will compete with H1 receptors, preventing histamine from attaching, causing histamine to not be released, helping to alleviate common allergic symptoms of rhinitis, allergic conjunctivitis, symptoms. symptoms of urticaria and allergic skin disorders. With manifestations such as itching, sneezing, runny nose, or the appearance of papules / rashes on the skin... However, in cases such as anaphylaxis, histamine is released massively, the use of loratadine was not effective. In that case, the drugs of choice for treatment are adrenaline and corticosteroids.
2. Uses of Clazidyne
Clazidyne (Loratadine) is a symptomatic treatment, so it is often prescribed to help relieve symptoms of allergies in cases such as:
Allergic rhinitis Allergic conjunctivitis Symptoms of urticaria with other symptoms symptoms: itching, white/red rash, .. and allergic skin disorders such as atopic dermatitis, contact dermatitis, .. Note: The drug should not be used in case the patient is sensitive to any of the ingredients. part of the drug.
3. How to use - Dosage of the drug Claazidyne
How to use : Clazidyne tablets are used orally. After oral administration of Clazidyne (loratadine), the antihistamine effect of the drug appears within 1 - 4 hours, reaches a maximum after 8-12 hours, and lasts more than 24 hours.
Dosage:
Adults and children 12 years of age and older: 10 mg/day, orally once a day, or 5 mg each time, every 12 hours. Children 2 - 12 years old: Body weight > 30 kg: 10 mg once a day; Body weight < 30 kg: 5 mg once daily. Severe liver failure: Adults and children ≥ 6 years old: 10 mg/time, once every 2 days; 2 - 5 years old: 5 mg / time, 2 times a day. Renal failure, Clcr < 30 ml/min: Adults and children ≥ 6 years old: 10 mg/time, once every 2 days; 2 - 5 years old: 5 mg / time, 2 times a day. If during the course of taking the medicine, you miss a dose, take it as soon as possible (usually 1-2 hours before the time prescribed by the doctor). However, if it is almost time for the next dose. , skip the missed dose and take your next dose at the prescribed time. If you have any questions regarding the use of Clazidyne or the medical condition you have, you should contact your doctor/pharmacist with expertise for answers.
In adults, when taking an overdose of Clazidyne (Loratadine) (dose: 40 - 180 mg), there are symptoms such as: Drowsiness, tachycardia, headache. In children, when the syrup is overdosed (in excess of 10 mg/day), there are extrapyramidal manifestations (typical symptoms are tremor, myoclonic tremor, muscle stiffness, or chorea,...) and palpitations. chest. In case of emergency or overdose with dangerous manifestations, it is necessary to immediately call the nearest 115 Emergency Center/medical facility for timely treatment.
4. Side effects when using the drug Clazidyne
Undesirable effects that may be encountered during the use of Clazidyne are as follows:
Common effects:
Adults: Headache, somnolence, fatigue, feeling of dry mouth. Children: Agitation, hyperactivity, rash, abdominal pain, stomatitis, pharyngitis, conjunctivitis, wheezing, hoarseness, upper respiratory tract infection, urinary retention, flu-like syndrome, viral infection . Uncommon effects:
Dizziness, dry nose, sneezing, bronchospasm, conjunctivitis. Rare effects:
You may appear some symptoms such as: Depression, disturbances of consciousness (confusion, ..), convulsions, tremors, cardiac arrhythmias (tachycardia, arrhythmia above). heart failure...), chest pain, palpitations, hypotension, syncope, thrombocytopenia, anorexia, nausea, liver dysfunction, liver necrosis, back pain, arthralgia, blurred vision, confusion menstruation, vaginitis, rash, urticaria, peripheral edema and anaphylactic reactions. It should be noted that this is not a complete list of the side effects of Clazidyne. If you have any other symptoms that have not been shown or have not been studied during the use of Clazidyne, or not specified in the instructions for use, you should immediately consult a qualified doctor / pharmacist. subject for timely advice and treatment.
5. Notes when using the drug Clazidyne
Inform your doctor about any medications or supplements you are taking. Clazidyne may interact with other drugs. Some of the drugs below may increase the concentration of Clazidyne in the blood, including: Cimetidine, Erythromycin, Ketoconazole, Quinidine, Fluconazole, Fluoxetine.... You should not use stimulants such as alcohol, beer, tobacco. ... during drug use to avoid unnecessary interactions. Need to read carefully the instructions for use of the drug or consult a doctor / pharmacist with expertise in taking Claazidyne with food, alcohol and tobacco... Use this medicine with caution in patients with impaired renal function. liver, kidney failure, dry mouth/risk of dry mouth. Should not be used during pregnancy and lactation. Above are some information and uses of Clazidyne, if you have any questions, please consult a qualified doctor / pharmacist for specific advice.
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