Uses of Clamidine

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1. What is Clamidine?

What is Clamidine? Clamidine drug has the main ingredient Loratadin and excipients just enough for one tablet. The drug is prepared in the form of hard capsules, packaged in a box of 1 blister, 10 blisters, each blister contains 10 tablets.
Pharmacodynamics: Loratadine is a potent, long-acting tricyclic antihistamine with selective peripheral H1-receptor antagonist activity.
Pharmacokinetics:
Absorption: After taking the active ingredient Loratadine is rapidly absorbed into the body. Peak plasma concentrations of Loratadine and its active metabolite are 1.5 and 3.7 hours, respectively. Distribution: Up to 97% of the drug is bound to plasma proteins. The volume of distribution of the drug in the body is 80-120 l/kg. Metabolism: Loratadine undergoes extensive first-pass metabolism in the liver by the cytochrome P450 microsomal enzyme system, which is converted to descarboethoxyloratadine. Elimination: Approximately 80% of the total dose of loratadine is excreted in the urine and faeces equally, as metabolites within 10 days.

2. Uses of Clamidine

Clamidine is indicated for the symptomatic treatment of adults and children over 2 years of age in the following cases:
Allergic rhinitis with signs such as sneezing, runny nose and itching. Allergic conjunctivitis with symptoms such as itchy eyes and burning sensation in the eyes. Symptoms of urticaria and other allergic skin disorders. Clamidine is contraindicated in patients who are allergic to the active ingredient Loratadin or other excipients in the drug.

3. Dosage and how to use Clamidine

3.1. Dosage Adults and children over 12 years old: 1 tablet per day. Children from 2-12 years old: use with a dose of 1 tablet / day when the child weighs over 30 kg, use a dose of 1⁄2 tablets / day. Clamidine should not be used in children under 2 years of age. If the patient is suffering from liver and kidney failure, the doctor or pharmacist should be informed to adjust the dose reduction accordingly. The recommended dose for this subject is 1⁄2 tablets per day or 1 tablet once every 2 days. 3.2. How to use Clamidine is made in the form of capsules that should be taken orally. Food does not affect the absorption of the drug, so it can be taken at any time of the day.

4. What to do in case of missed dose or overdose of Clamidine?

In case of forgetting a dose:
The patient should take the missed dose as soon as he remembers. If it is too close to your next dose, skip it and take your next dose as directed by your doctor. Do not take 2 doses at the same time to make up for the missed dose. In case of drug overdose:
When you overdose, you may experience symptoms of tachycardia, drowsiness, headache. Treatment: take the victim immediately to the nearest medical facility for timely emergency treatment. List to the doctor the drugs that the patient is using, including prescription and non-prescription drugs, functional foods, vitamins, etc. The patient needs intervention for symptomatic treatment and supportive treatment.

5. Clamidine side effects

During the use of Clamidine , you may experience the following undesirable effects:
Headache, dry mouth. Dizziness, dry nose and sneezing, conjunctivitis. Depression, tachycardia, arrhythmia, palpitations, urticaria, anaphylaxis may even occur.

6. Clamidine drug interactions

Please list and tell your doctor about all the medicines you are taking to avoid possible harmful interactions when taking different drugs together. Drugs that may interact with Clamidine such as:
Loratadine plasma concentrations were increased when co-administered with drugs such as ketoconazole, erythromycin or cimetidine in clinical trials, but no significant changes were observed. clinical (including electrocardiogram). Caution should be exercised when co-administering other medicinal products with an inhibitory effect on hepatic metabolism until drug interaction studies have been adequately completed. Clamidine should be discontinued 48 hours before skin testing, as antihistamines can prevent and reduce positive skin reactions.

7. Some notes when using Clamidine?

Some notes when taking Clamidine are as follows:
If you have impaired liver function or are being treated for hepatitis with antiviral drugs, tell your doctor or pharmacist to consult first. while taking Clamidine. Clamidine contains lactose monohydrate, so if patients have rare hereditary problems of lactose intolerance, lactase deficiency or glucose-galactose malabsorption, this medicine should not be used in these patients. . Similar to other antihistamines, may prevent or reduce positive skin test reactions. Therefore, Clamidine should be administered at least 48 hours prior to skin testing. Do not give this medicine to children under 2 years of age, unless there are special indications that cannot be replaced by other treatments from your doctor. Like all medicines, Clamidine should be avoided in pregnant women. Clamidine is excreted in breast milk, so if you are breastfeeding you should not take this medicine. If it is necessary to use the drug, the benefits and risks must be considered, and breastfeeding should be discontinued during the use of the drug. Currently, clinical trials have shown that the drug does not affect the ability to drive and use machines. However, there have been cases, though very few, of feeling drowsy after taking Clamidine. If you feel drowsy after taking this medicine, do not drive or operate machinery. Above is the important information of Clamidine, carefully reading the instructions before use and strictly following the doctor's instructions will bring the best treatment results for the patient. Follow Vinmec International General Hospital website to get more health, nutrition and beauty information to protect the health of yourself and your loved ones in your family.

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