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Cefurich 500 is often used in the treatment of respiratory tract infections, urinary tract infections - genitals,... So what is Cefurich 500 and how is it used?
1. What is Cefurich 500?
Cefurich 500 is an oral cephalosporin antibiotic. Cefuroxime 500mg is prepared in the form of tablets, each tablet has the main ingredient is Cefuroxime 500mg.
Cefuroxime is a semi-synthetic broad-spectrum antibiotic, belonging to the second generation cephalosporin group. Cefuroxime has an antibacterial effect by inhibiting bacterial cell wall synthesis by binding to proteins involved in the composition of bacterial cell membranes. As a result, the bacterial cell wall will weaken and become unstable under the influence of osmotic pressure.
Cefurich 500 is indicated in the following cases:
Lower respiratory tract infections such as acute and chronic bronchitis, pneumonia. Upper respiratory tract infections such as otitis media, sinusitis, tonsillitis, pharyngitis. Urogenital infections such as pyelonephritis, cystitis, urethritis. Skin and soft tissue infections such as boils, pustules, impetigo. Treatment of gonorrhea, uncomplicated gonococcal urethritis and cervicitis. Cefurich 500mg drug is contraindicated in the following cases:
People with hypersensitivity to cefuroxime or any ingredient of the drug. Patients with a history of allergy to any Cephalosporin, history of severe hypersensitivity to other beta-lactam antibiotics.
2. Dosage and how to use Cefurich 500
Cefurich 500 is taken orally, dissolve the effervescent tablet in a glass of water before taking it.
Recommended dosage of Cefurich 500 for adults:
In most cases, infections respond to a dose of 250mg twice daily. For severe pneumonia and bronchitis use 500mg x 2 times/day. For urinary tract infections use 125mg or 250mg, twice a day. Treatment of cervical gonorrhea or uncomplicated gonorrhea urethritis or uncomplicated rectal gonorrhea in women: Use a single dose of 1g. In new Lyme disease: Use a dose of 500mg / time, 2 times a day, for 20 days. Dosage of Cefurich 500 is recommended for children:
Children from 3 months to 2 years old: Use a dose of 10mg/kg (maximum 125mg), twice a day. Children from 2 to 12 years old: Use dose 15mg/kg (maximum 250mg), twice daily. Patients with hepatic impairment do not require dose adjustment of Cefurich 500. Patients with renal impairment: In patients with creatinine clearance < 20ml/min, the dose of Cefurich 500 should be reduced by half with an interval of 2 doses of Cefurich 500. 24 hours.
Acute symptoms when using Cefurich 500 drug overdose: Most drugs only cause nausea, vomiting and diarrhea. However, overdose can cause neuromuscular hyperexcitability reactions and convulsions, especially in patients with renal failure.
Treatment of drug overdose Cefurich 500 includes: Respiratory protection, ventilation support and intravenous fluids. If convulsions occur, the drug should be discontinued immediately, anticonvulsant therapy may be used if clinically indicated. Hemodialysis can remove Cefurich 500 from the blood, but in most cases treatment is supportive or symptomatic.
If you forget to take a dose of Cefurich 500, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as usual.
3. Side effects of the drug Cefurich 500
During the use of Cefurich 500mg, you may experience the following side effects:
Systemic symptoms: Candida infection, anaphylactic reactions. Gastrointestinal system: Nausea, vomiting, diarrhea, these symptoms usually disappear when the drug is stopped. Skin: Urticaria, erythema multiforme, pruritus, Stevens - Johnson syndrome. Nervous: Headache, dizziness. If you experience any side effects while using Cefurich 500, you should immediately inform your doctor for timely treatment.
4. Interaction of the drug Cefurich 500 with other drugs
Ranitidine and sodium bicarbonate reduce the effect of cefuroxime. Cefurich 500 should be administered at least 2 hours after an antacid or H2 blocker. High-dose probenecid reduces renal clearance of cefuroxime, resulting in higher and more prolonged blood levels of cefuroxime. Co-administration of Cefurich 500 with Aminoglycosides increases the possibility of nephrotoxicity. Cefurich 500 may cause a false-positive reaction in the oxidizing glucose test but has no effect on the enzyme reaction. Reduces the effect of female sex hormones: Because Cefurich 500 can affect the microflora in the intestines, reducing estrogen reabsorption, thereby reducing the effectiveness of oral contraceptives containing estrogen and progesterone. Co-administration of Cefurich 500 with anticoagulants increases INR. Cefurich 500 is often used in the treatment of respiratory tract infections, urinary tract infections - genital infections,... To ensure effective treatment and avoid unwanted side effects, patients need to read carefully. instructions or consult a doctor, pharmacist for advice.
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