This is an automatically translated article.
Cbizentrax contains the main ingredient is Albendazole with a concentration of 400mg - a Benzimidazol carbamate derivative, with a broad spectrum of activity on intestinal worms. It is used to treat infection with one or more types of intestinal parasites and a number of other conditions.
1. What is Cbizentrax?
Cbizentrax is a brand name of the active ingredient Albendazole, only used when prescribed by a doctor, patients do not arbitrarily use it without a prescription. The drug is a product of the branch of Agimexpharm Pharmaceutical Joint Stock Company - Agimexpharm pharmaceutical factory and is prepared in the form of film-coated tablets (box of 1 blister, 1 tablet per blister).
Each Cbizentrax tablet contains 400mg of Albendazole and some other excipients just enough.
2. What are the uses of Cbizentrax?
Medicines are mainly used to treat infection with one or more types of intestinal parasites. The drug has broad activity on intestinal worms such as:
Hookworm (Ancylostoma duoenale, Necator americanus). Roundworm (Ascaris lumbricoides). Pinworms (Enterobius vermiculasris). Strongyloides stercoralis (Strongyloides stercoralis). Hairworm (Trichuris trichiura). Capillaria worm (Capillaria philippinensis). Trichinella spiralis (Trichinella spiralis). Migratory larval form in muscle, skin or viscera caused by Toxocara canis or T. cati. Tapeworms and tissue tapeworm larvae. In addition, the drug is also effective against larval disease of tapeworm (Taenia solium) in the nervous system, cysticercosis (Echinococcus granulosus) in the liver, lung and peritoneum or Giardia disease.
Albendazole has a similar mechanism of action to other Benzimidazole dewormers. It is associated with the tubules of the parasite, inhibiting the polymerization of the tubules into the microtubules of the cytoplasm - which are necessary organelles for the normal functioning of the parasite's cells. Besides, Albendazole also works to kill eggs, larvae and adult worms.
Albendazole inhibits glucose absorption, so worms lose energy, not enough to live, immobilize and then die.
After a single oral dose of 400 mg Albendazole, peak concentrations of the sulfoxide metabolite occur in 1-4 hours. When taken with high-fat food, plasma concentrations increase 2-4 times. The drug is eliminated mainly through the feces. The half-life is about 9 hours.
3. Instructions for using Cbizentrax
May be chewed, swallowed or crushed and mixed with food. The drug should be used at the same time of day to increase adherence.
Dosage depends on the causative agent:
Roundworm, pinworm, hookworm, whipworm: Adults and children over 2 years old: Take a single dose of 400mg. Can be treated again after 3 weeks. Children 2 years and under: Take a single dose of 200mg. Can be treated again after 3 weeks. Skin migratory larvae: Adults: A single dose of 400mg per day for 3 days. Children: Use at a dose of 5mg/kg per day, orally for 3 days. Follicular disease: Adults: Oral at a dose of 800mg per day, taken for 1 month. Repeat treatment if necessary. Children from 6 years and older: Use at a dose of 10-15mg/kg per day, orally for 1 month. Repeat treatment if necessary. Children under 6 years: The dose has not been determined. Brain fluke larvae: The common dose for adults and children is 15mg/kg per day, used for 1 month. Repeat treatment after 3 weeks if necessary. Tapeworms, strongyloides: Adults and children over 2 years: Take a single dose of 400mg per day, orally for 3 days. Repeat treatment after 3 weeks if necessary. Children 2 years and younger: Take a single dose of 200mg per day for 3 days. Repeat treatment after 3 weeks if necessary. Giardia disease: Use with a single dose of 400mg a day, orally for 5 days. Liver fluke: The common dose for children and adults is 10mg/kg per day, taken for 7 days. For pregnant women: Should not be used unless prescribed by a doctor and must be treated. Moreover, after taking the drug, the patient must not become pregnant for at least 1 month. If you find out you are pregnant while taking the drug, you should stop using it immediately. Lactation: The extent to which the drug is excreted in breast milk is not known, so extreme caution should be exercised unless directed by a physician. Before prescribing Cbizentrax, tell your doctor if you have one of the following contraindications:
Hypersensitivity to Benzimidazole group or other components of the drug. Pregnant or breastfeeding. History of bone marrow toxicity. Liver failure. Cirrhosis. Lactose intolerance. Before treating neurocysticercosis, the patient should have a careful eye examination to rule out retinal damage. Because when using the drug can cause irreversible damage when treating cysts in the eyes or spinal cord.
When drug overdose occurs, the patient should be taken to the hospital immediately for gastric lavage, activated charcoal and emergency measures.
Consideration should be given to use in patients with hepatic impairment because the drug is metabolized by the liver, whereby hepatotoxicity may occur. Before treatment, liver function tests should be performed.
The drug does not affect the ability to drive and use machines.
Do not tear the medicine packaging, store at a temperature below 30oC and in a dry place, protected from light.
4. Drug interactions
When used together with the following drugs may increase drug interactions:
Coadministration with Dexamethasone or Praziquantel will increase the steady-state plasma concentration of the drug by about 50%. In patients with cysticercosis, when used in combination with cimetidine will increase the drug concentration in bile and cyst fluid by about 2 times.
5. Side effects of the drug Cbizentrax
Possible side effects of Cbizentrax include:
Fever. Headache. Dizzy. Increase liver enzymes. Stomachache. Nausea and vomiting. Digestive disorders. Limit eating grapefruit or grapefruit juice when using the drug because it can increase side effects.
The drug also rarely causes leukopenia (most commonly leukopenia). Therefore, before treatment, it is also necessary to have a blood count test to evaluate.
Very rarely cause allergies. However, if it happens, it is necessary to take the patient to the hospital immediately for treatment according to the anaphylactic shock treatment protocol issued by the Ministry of Health.
In a nutshell, Cbizentrax is a prescription medication used to treat infections with one or more types of intestinal parasites. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Sulfaprim exactly as directed by your doctor.
