This is an automatically translated article.
Methocarbamol is an active ingredient that relaxes muscles and relieves pain. This active ingredient is present in Carbamol BFS product of Hanoi CPC1 Pharmaceutical Joint Stock Company. So what is Carbamol BFS and how is it used?
1. What is Carbamol BFS?
Carbamol BFS has the main ingredient Methocarbamol 1000mg/10ml. Carbamol BFS drug is manufactured by Hanoi CPC1 Pharmaceutical Joint Stock Company (Vietnam), circulated in our country with the registration number VD-31615-19. Carbamol BFS is prepared in the form of an injection solution, each box includes 1, 5, 10 or 20 ampoules of 10 ml.
The Methocarbamol component in Carbamol BFS has a long-lasting muscle relaxant effect on skeletal muscles through a selective inhibitory mechanism on the central nervous system, especially inhibition of interneurons. The uses of Methocarbamol include calming the central nervous system, inhibiting muscle contractions, reducing central pain, and assisting in the relief of acute pain and excessive muscle spasms.
In treatment, Carbamol BFS gives quick action after only 30 minutes, high and long-lasting pain relief, and almost no serious side effects. The usual dose of Methocarbamol does not affect the normal muscle strength of the patient, and does not inhibit muscle reflexes. Active substance Methocarbamol has no effect on motor neurons, and at non-toxic doses, it has also been reported to have effects on the upper medullary nervous system.
Pharmacokinetics of Carbamol BFS:
Absorption: Methocarbamol is rapidly and almost completely absorbed when administered via the gastrointestinal tract and parenteral route. Peak plasma concentrations are reached after approximately 1-2 hours of administration; Distribution: Methocarbamol is widely distributed in tissues such as liver, kidney, lung, brain, spleen and skeletal muscle; Elimination: The half-life of Methocarbamol is 0.9-1.8 hours. This active substance is rapidly and almost completely eliminated in the urine.
2. Indications and contraindications of Carbamol BFS
Carbamol BFS products are indicated in the following cases:
Treatment of acute back pain caused by muscle spasms or herniated discs; Relieve pain from fractures or dislocations; Relieve muscle spasms caused by nerve irritation, after trauma or orthopedic surgery; Carbamol BFS is also used in diseases such as fibromyalgia, scoliosis, spondylolisthesis, bruxism, myositis and leg cramps at night. The use of Carbamol BFS is contraindicated in the following cases:
Patients with hypersensitivity to Methocarbamol or any ingredient in Carbamol BFS; The patient is in a coma, with brain damage; Patients with myasthenia gravis; The patient has a history of seizures.
3. Dosage of Carbamol BFS
The recommended dosage of Carbamol BFS is as follows:
Adults: 2-6g/day divided into 4 uses; Children over 12 years: The recommended dose is 15mg/kg, may be repeated every 6 hours; The dose of Carbamol BFS must be adjusted according to the age, severity of the disease and tolerability of the individual patient. In severe cases, Methocarbamol can be used for up to 4-6 months. To increase pain relief, patients should be prescribed Carbamol BFS in combination with NSAIDs or other analgesics:
1-3g Methocarbamol in combination with 100-300mg Nimesulid daily; 1-3g Methocarbamol combined with 0.5-2g Paracetamol per day. Carbamol BFS overdose and management:
Methocarbamol overdose symptoms may include nausea, dizziness, more serious can show CNS depression when using doses over 10g; Carbamol BFS overdose cases need to stop using the drug immediately, then carry out gastric lavage and support symptomatic treatment. Conversely, patients who miss a dose of Carbamol BFS should be compensated as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.
4. Side effects of Carbamol BFS
Some of the side effects noted during the use of Carbamol BFS include:
Drowsiness; Dizzy; Nausea, metallic taste in the mouth, anorexia or gastrointestinal symptoms; In rare cases, manifestations of allergic reactions such as urticaria, pruritus, skin rash, conjunctivitis with nasal congestion.
5. Pay attention when using Carbamol BFS
Efficacy and safety when using Methocarbamol for children under 12 years of age have not been determined, so Carbamol BFS is not indicated for this subject. Carbamol BFS should be used with caution in patients with impaired hepatic or renal function. In therapeutic doses, Methocarbamol can reduce the patient's ability to concentrate on tasks that require mental alertness or physical health, such as operating machinery or driving. Therefore, Carbamol BFS should not be prescribed to people who drive or operate machinery. Because the safety of Methocarbamol has not been established during pregnancy, Carbamol BFS is not suitable for use in pregnant patients. It is not known whether Methocarbamol is excreted in human milk, so Carbamol BFS should be used with caution in lactating women. In terms of drug interactions, avoid co-administration of Carbamol BFS with other CNS depressants (including alcohol), anorexia, antimuscarinic or psychotropic agents.
