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Candesartan 8mg is known as a cardiovascular drug. So what is the effect of Candesartan 8mg and how is it used?
1. What is Candesartan 8mg?
Candesartan 8mg drug has the main ingredient containing the active ingredient Candesartan cilexetil with a concentration of 8mg and excipients just enough for 1 tablet, made in the form of tablets, packed according to box specifications of 3 blisters x 10 tablets / 1 blister.
2. Effects of Candesartan 8mg
With active ingredients and active ingredients, Candesartan 8mg is indicated for use in the following cases:
Candesartan 8mg is indicated in the treatment of hypertension in children from 6 years old to <18 years old and adults. Treatment in heart failure grade II and III. Treatment in chronic congestive heart failure. Candesartan is not contraindicated in the following cases:
Do not use in patients with a history of hypersensitivity to Candesartan or any of the excipients of the drug. Do not use for patients with cholestasis, severe liver failure. Do not use for children < 1 year old, pregnant women (especially in the first and third months of pregnancy). Patients with heart failure have blood creatinine > 30 mg/l, blood potassium > 5 mmol/l or creatinine clearance < 30 ml/min. Candesartan 8mg should not be combined with drugs containing Aliskiren in patients with renal impairment (GFR < 60 ml/min/1.73 m2) or diabetes mellitus.
3. Usage and dosage of Candesartan 8mg
3.1. How to use Candesartan 8mg Candesartan 8mg is produced in the form of tablets, used orally, can be taken before, during or immediately after a meal.
3.2. Dosage of the drug Candesartan 8mg Hypertension:
In adults:
Usual dose: once a day with a dose of 8 mg. Most effects will be achieved within 4 weeks. The dose may be increased to 16 mg once daily in some patients not adequately controlled, up to a maximum once-daily dose of 32 mg. In patients with intravascular volume depletion: in patients at risk of hypotension, an initial dose of 4 mg may be considered. In patients with hepatic impairment: Candesartan is contraindicated in patients with severe hepatic impairment or cholestasis, for mild to moderate hepatic impairment an initial daily dose of 4 mg may be used. In patients with renal impairment: Even in patients on hemodialysis, a starting dose of 4 mg once daily may be used. In patients with very severe renal failure or end-stage renal failure, no treatment is indicated. In children from 6 years old to under 18 years old:
Children weighing less than 50 kg: apply a starting dose of 4 mg once a day, for patients with intravascular volume depletion should use a lower dose, adjust the dose according to the patient's needs. response of the patient, the maximum daily dose is 8mg/time. Children with weight greater than or equal to 50kg: apply a starting dose of 4mg once a day, for patients with intravascular volume depletion should use a lower dose, adjust the dose according to the patient's response, the maximum dose 16mg/time per day. Heart failure:
The recommended starting dose is 4mg once a day, each session is not less than 2 weeks apart, can double the dose, the maximum dose is 32mg once a day.
4. Undesirable effects of the drug Candesartan 8mg
In addition to the therapeutic effects when patients use Candesartan 8mg, there may also be unwanted effects as follows:
Common side effects such as fever, weakness, dizziness, paresthesia, gastroenteritis, dyspepsia, palpitations, tachycardia, hypertriglyceridemia, hyperglycemia, elevated creatine phosphokinase, uremia, myalgia, epistaxis, neurasthenia, anxiety , lethargy, difficulty breathing, excessive sweating, rash, bloody urine. Less common side effects such as: myocardial infarction, angina pectoris, angioedema. Very rare side effects such as: liver dysfunction, hepatitis, leukopenia, neutropenia, agranulocytosis, hyponatremia, hyperkalemia, renal failure, kidney damage, urticaria , itchy.
5. Candesartan 8mg drug interactions
Because of the effect of increasing the concentration of potassium in the blood of Candesartan 8mg, caution should be taken when co-administering Candesartan 8mg with drugs that can increase blood potassium levels such as potassium supplements, potassium-sparing diuretics. (Spironolactone).
Careful monitoring of plasma lithium levels is required when Candesartan 8mg and Lithium are co-administered, as there is an increase in plasma lithium concentrations during co-administration of these two drugs.
Co-administration of Candesartan 8mg with NSAIDs may reduce the antihypertensive effect and increase the risk of impaired renal function (hyperkalemia, acute renal failure).
Do not use fermented foods or tobacco, alcohol, alcoholic beverages during the use of Candesartan 8mg.
6. Notes when using Candesartan 8mg
Caution should be exercised in patients with heart failure, as the use of Candesartan 8 mg may cause hypotension, a temporary reduction in the dose of Candesartan 8 mg is required. Patients with congestive heart failure may experience hyperkalemia when using Candesartan 8 mg, especially when the patient is taking concomitant ACE inhibitors or potassium-sparing diuretics. The use of Candesartan 8 mg is not recommended in patients with primary hyperaldosteronism. In patients receiving Candesartan 8 mg or ACE inhibitors, there may be a marked deterioration in renal function (renal failure, progressive azotemia, oliguria, death). Hypotension may occur during anesthesia and surgery in patients receiving Candesartan 8 mg. Candesartan 8mg should not be used by pregnant women, when pregnancy is detected, it is necessary to stop using Candesartan 8mg immediately. It is recommended that patients be aware of symptoms of fatigue and lightheadedness, which may occasionally occur during treatment with Candesartan 8mg.
7. Storage of Candesartan 8mg
Store Candesartan 8mg medicine in a cool, dry place, avoid direct exposure to sunlight and high temperature, because it can change some ingredients in the drug, the appropriate storage temperature is below 30oC. Keep the medicine at a height, out of the reach of children.
The above are the uses of Candesartan 8mg, patients need to carefully consult and discuss with a specialist doctor before taking the drug to achieve high efficiency.
