Uses of Caduet

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1. What is a brand-name drug Caduet?

What is a brand-name drug Caduet? Caduet drug is a combination product between 2 active ingredients, Amlodipine and Atorvastatin:
Atorvastatin is an active ingredient in the group of HMG-CoA reductase inhibitors (also known as statins). The effect of Atorvastatin is to reduce blood levels of "bad" cholesterol (LDL-C) and triglycerides, and increase levels of "good" cholesterol (HDL-C); Amlodipine is a calcium channel blocker with the main effect of vasodilating, improving blood flow and helping to increase myocardial contractility to make it easier to eject blood.

2. What are the effects of Caduet?

What does Caduet do? Caduet is used mainly in the treatment of hypertension or angina pectoris and for the prevention of the risk of stroke, myocardial infarction and other cardiovascular complications in patients with type 2 diabetes, coronary heart disease, and type 2 diabetes. or have other risk factors.
Caduet is for use only in adults and children 10 years of age and older.

3. Issues to note before using Caduet

Caduet should not be used if the patient has the following problems:
History of allergy to Amlodipine or Atorvastatin; Have liver disease; Caduet should not be used during pregnancy due to the risk of harm to the unborn baby. Patients should use effective contraception during treatment with Caduet. If an unplanned pregnancy occurs during treatment, the patient should stop taking Caduet and notify the doctor immediately; Do not breast-feed while using Caduet. Before taking Caduet, patients should inform their treating doctor of the following:
History of kidney disease; History of cardiovascular disease; Muscle pain or weakness; History of diabetes, thyroid disorders; The patient consumed more than 2 units of alcohol per day. Atorvastatin in Caduet can cause breakdown of muscle tissue and lead to kidney failure. The risk of this serious side effect is higher when using Caduet in women, older adults, people with kidney disease, or poorly controlled hypothyroidism.
Some other drugs can increase the risk of serious muscle problems when used together with Caduet and require a plan to be adjusted by your doctor, including:
Colchicine: Cyclosporine; Medicines containing Niacin; Antibiotics Clarithromycin, Erythromycin; Antifungal drugs Itraconazole, Ketoconazole, Voriconazole; Some drugs to treat blood cholesterol disorders such as Gemfibrozil, Fenofibric Acid, Fenofibrate; Antiviral drugs that treat hepatitis C or HIV such as Boceprevir, Darunavir, Fosamprenavir, Lopinavir, Nelfinavir, Ritonavir, Saquinavir, Telaprevir, and Tipranavir.

4. How to take Caduet

Patients need to use Caduet exactly as prescribed by their doctor and follow the manufacturer's instructions. Patients should take Caduet at the same time each day, before or after meals. When taking Caduet tablets should be swallowed whole, do not chew or crush, so the patient should tell the doctor that the patient has difficulty swallowing.
Patients may have to stop taking Caduet for a short time if they have the following problems:
Uncontrollable seizures; Electrolyte imbalances such as hyperkalemia or hypokalemia; Severe low blood pressure; Infection or serious illness; Need surgery or a medical emergency; Patients need regular medical check-ups while taking Caduet. Treatment with this product will have to be prolonged, patients must still take Caduet even if they feel fine, because high blood pressure or high cholesterol usually causes no special symptoms.
Caduet is part of a complete regimen in addition to proper diet, exercise and weight control.
Recommended dose of Caduet in adults:
Starting dose: Caduet 5/10 (Amlodipine/Atorvastatin) or Caduet 5/20 mg, orally once a day; Maximum dose: Caduet 10/80, taken once a day; Some notes on Caduet dosing:
Low-weight or elderly patients can start treatment with low-dose Amlodipine (2.5mg), then adjust according to clinical response; Most patients with coronary artery disease need to use Amlodipine 10mg daily for maximum effectiveness; Patients requiring a reduction of more than 45% Low Density Lipoprotein (LDL) may be started with Atorvastatin at 40 mg/day; The maximum effect of Amlodipine can be achieved after 1-2 weeks and with Atorvastatin after 2 to 4 weeks of dosing; Atorvastatin has not been studied in the treatment of hyperchylomicrons (Fredrickson classifications I and V).

5. Caduet . side effects

Patients need urgent medical attention if there are signs of an allergic reaction to Caduet medicine such as hives, difficulty breathing, swelling of the face, lips, tongue or throat.
In rare cases, Atorvastatin can cause breakdown of muscle tissue and lead to kidney failure. Patients should contact their doctor immediately if symptoms such as unexplained muscle pain, pain, or weakness are present, especially if accompanied by other symptoms such as fever, unusual tiredness, or urine that contains urine. dark color.
Contact the treating doctor immediately if the patient taking Caduet has the following problems:
Muscle stiffness, tremors or abnormal muscle movements; Weakness in the hips, shoulders, neck and back; Difficulty lifting arms, difficulty climbing stairs or standing still; Severe drowsiness, feeling that you are about to pass out; worsening chest pain that radiates down the arm or up the jaw with nausea, sweating, or ill feeling; Liver problems such as right upper quadrant pain, loss of appetite, fatigue, dark urine, jaundice, yellow eyes. Other common side effects of Caduet may include:
Muscle or joint pain; Diarrhea; Nausea, abdominal pain; Swollen feet or ankles.

6. Caduet . drug interactions

If the patient is taking Nitroglycerin for angina, it should be continued while taking Caduet.
Patients need to have a diet with limited fat or cholesterol, otherwise Caduet will not be effective.
Limit alcohol use, as they can increase blood triglycerides, and increase the risk of liver damage or increase some of the side effects of Caduet.
Grapefruit can interact with Caduet and lead to unwanted side effects. Therefore, patients need to avoid using grapefruit and grapefruit products when taking Caduet;
Certain other medicines may increase your risk of serious muscle problems from Caduet . It is very important for the treating physician to know what medications the patient is taking. Therefore, the patient should inform the doctor about all other medicines being taken, especially:
Antibiotics or antifungal drugs; Oral contraceptives; Other anti-hypercholesterolemic drugs; Antiviral drugs for hepatitis C or HIV; Drugs for the treatment of cardiovascular diseases; Medicines to prevent organ rejection. In short, Caduet is a combination product of a calcium channel blocker (Amlodipine) and a statin (Atorvastatin) active ingredient. The drug is used mainly in the treatment of hypertension, angina pectoris and prevention of the risk of stroke, myocardial infarction and other cardiovascular complications in patients with type 2 diabetes, coronary heart disease or have other risk factors. To ensure effective use, patients need to carefully read the instructions, and strictly follow the instructions of the doctor or pharmacist.
Store Caduet medicine in a cool, dry place, away from direct light. Keep medication out of reach of children and household pets.
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Reference source: drugs.com